Glycoside Hydrolase Family 36

Activities in FamilyStachyose synthase / galactinol-raffinose galactosyltransferase (EC 2.4.1.67);
Raffinose synthase / galactinol-sucrose galactosyltransferase (EC 2.4.1.82);
α-galactosaminidase (EC 3.2.1.-);
Blood group B α-1,3-galactosidase (EC 3.2.1.-);
Raffinose exo-α-1,6-galactosidase (EC 3.2.1.-);
α-galactosidase (EC 3.2.1.22);
α-N-acetylgalactosaminidase (EC 3.2.1.49);
[retaining] β-L-arabinopyranosidase / β-L-arabinosidase (EC 3.2.1.88);
Mechanism Retaining a
ClanGH-D
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorAsp (experimental)
NoteMechanistic commonality with family GH27 demonstrated by Comfort et al. (2007) Biochemistry, 46: 3319-3330 (PMID: 17323919)
External resourcesCAZypedia; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (14317); Uniprot accession (95); PDB accession (38); 3D entries (10); cryst (0)
| 1 | ... | 119 | 120 | 121 | 122 | 123 | 124 | 125 | 126 | 127 | ... | 132 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 A0O31_01574   Thermus brockianus GE-1 APD09683.1    
 α-galactosidase (AgaT) 3.2.1.22 Thermus brockianus ITI360 AAD33668.1 Q9X6C7  
 TbrSNM41_17640   Thermus brockianus SNM4-1 BDG17030.1    
 TSC_c19210   Thermus scotoductus SA-01 ADW22534.1    
 α-galactosidase   Thermus sp. IB-21 AAN05444.1    
 MI302_08880   Thermus sp. NEB1569 ULR40228.1    
 KQ693_12130   Thermus sp. PS18 UZX15356.1    
 α-galactosidase (AglA) 3.2.1.22 Thermus sp. T2 BAA76597.1
CAB65477.1
Q9WXC1  
 TTHNP4_00222 (GalA)   Thermus thermophilus VCU54814.1    
 TthAA11_23180   Thermus thermophilus AA1-1 BCZ88136.1    
 TthAA22_22990   Thermus thermophilus AA2-2 BCZ90494.1    
 TthAA220_22400   Thermus thermophilus AA2-20 BBL83456.1    
 TthAA229_22050   Thermus thermophilus AA2-29 BBL85724.1    
 TthAA37_23240   Thermus thermophilus AA3-7 BCZ93135.1    
 TthAK1_21690   Thermus thermophilus AK1 BCZ95552.1    
 α-galactosidase (AgaT;TTP0072) 3.2.1.22 Thermus thermophilus HB27 AAS82402.1 Q746I3  
 RB649_10645   Thermus thermophilus HB27 WMV96557.1    
 HB27c_P0076   Thermus thermophilus HB27c QMV32116.1    
 V4943_10675   Thermus thermophilus HB27_delta_csm3 WVY28273.1    
 TthHB5002_10230   Thermus thermophilus HB5002 BCP97920.1    
 TthHB5008_10200   Thermus thermophilus HB5008 BCQ00250.1    
 TthHB5018_d26450   Thermus thermophilus HB5018 BCP67711.1    
 TthHB5018_b22930 (fragment)   Thermus thermophilus HB5018 BCP67359.1    
 α-galactosidase (TtGalA; TTHB115) 3.2.1.22 Thermus thermophilus HB8 BAD71911.1 Q53W51 6LCJ[A,B,C,D,E,F]
6LCK[A,B,C]
6LCL[A,C,E]
 TthHB8_30470   Thermus thermophilus HB8_001 BDE46361.1    
 TthHC11_22600   Thermus thermophilus HC11 BBL94726.1    
 JCM10941_21630   Thermus thermophilus JCM10941 BDA38798.1    
 TtJL18_2279   Thermus thermophilus JL-18 AFH40112.1    
 K7H19_11105   Thermus thermophilus N-1 QZY59600.1    
 Ththe16_2262   Thermus thermophilus SG0.5JP17-16 AEG34625.1    
 TthSNM11_11810   Thermus thermophilus SNM1-1 BDG18978.1    
 TthSNM17_21590   Thermus thermophilus SNM1-7 BDG22497.1    
 TthSNM33_23090   Thermus thermophilus SNM3-3 BDG25115.1    
 TthSNM66_21300   Thermus thermophilus SNM6-6 BDG27494.1    
 TthSNM76_24160   Thermus thermophilus SNM7-6 BDG30206.1    
 TthTF19_22080   Thermus thermophilus TF19 BFH77052.1    
 TthTF21_23380   Thermus thermophilus TF21 BFH79620.1    
 TthTF24_22690   Thermus thermophilus TF24 BFH81975.1    
 TthTF25_23810   Thermus thermophilus TF25 BFH84458.1    
 TthTF27_22740   Thermus thermophilus TF27 BFH86782.1    
 TthTF28_21050   Thermus thermophilus TF28 BFH89004.1    
 α-galactosidase (AgaT) 3.2.1.22 Thermus thermophilus TH125 AAD32628.1 Q9X6D2  
 TTMY_0016   Thermus thermophilus TMY BAW00430.1
BDB11155.1
   
 V4942_10675   Thermus thermophilus TTHB27_delta_cmr4 WVY30478.1    
 AKL02_004500   Thioclava electrotropha Elox9 QPZ90213.1    
 BMG03_05620   Thioclava nitratireducens 25B10_4 AQS47330.1    
 P0N61_04110   Thioclava nitratireducens M1-LQ-LJL-11 WGT51230.1    
 EW093_05815   Thiospirochaeta perfilievii QEN04241.1    
 EYR00_05160   Thomasclavelia ramosa DSM 1402 QMW74123.1    
 I6I62_08190   Thomasclavelia ramosa FDAARGOS_1105 QQV07607.1    
 I6I63_05130   Thomasclavelia ramosa FDAARGOS_1106 QQY28594.1    
 I6G63_13075   Thomasclavelia ramosa FDAARGOS_906 QPS12607.1    
 NQ543_10185   Thomasclavelia spiroformis DSM 1552 UWO89314.1    
 NQ543_02315   Thomasclavelia spiroformis DSM 1552 UWO90106.1    
 Tola_2117   Tolumonas auensis DSM 9187 ACQ93716.1    
 TRBR_11140   Treponema bryantii JCM 32280 BDC93017.1    
 TRBR_15280   Treponema bryantii JCM 32280 BDC93431.1    
 TRBR_14270   Treponema bryantii JCM 32280 BDC93330.1    
 KP613_05850   Treponema denticola ASLM WYM96756.1    
 TDE1453   Treponema denticola ATCC 35405 AAS11970.1
NP_972059.1
   
 E4N77_03790   Treponema denticola ATCC 700771 UTY25891.1    
 E4N79_06185   Treponema denticola CD-1 UTC87749.1    
 OE909_06940   Treponema denticola KCOM 3500 UYT06698.1    
 E4N90_06565   Treponema denticola OKA3 UTD07620.1    
 E4N80_03970   Treponema denticola OMZ 823 UTD04695.1    
 E4N83_06065   Treponema denticola OMZ 850 UTC97834.1    
 E4N84_06600   Treponema denticola OMZ 852 UTC92774.1    
 HGJ18_03960   Treponema denticola OMZ 853 UTC82399.1    
 HO345_06170   Treponema denticola OMZ 854 UTD12593.1    
 E4N85_06010   Treponema denticola OMZ 898 UTC95304.1    
 E4N91_06255   Treponema denticola OT2B UTC85251.1    
 TREPR_1966   Treponema primitia ZAS-2 AEF85385.1    
 JO40_12170   Treponema putidum OMZ 758 AIN94740.1    
 E4N74_06045   Treponema putidum OMZ 835 UTY33630.1    
 E4N75_06375   Treponema putidum OMZ 846 UTY31190.1    
 E4N76_06945   Treponema putidum OMZ 847 UTY28763.1    
 DYE49_12040   Treponema rectale CHPA QOS41139.1    
 DYE50_07900   Treponema ruminis RU1 QSI02489.1    
 TRSA_25680   Treponema saccharophilum JCM 32279 BDC97469.1    
 HYB91_06020   Treponema sp. B152 UTD10092.1    
 E4O05_08445   Treponema sp. OMZ 787 UTC61582.1    
 FAZ95_33415   Trinickia violacea DHOD12 QCP54976.1    
 R1T40_03630   Tritonibacter scottomollicae LC.270.F.C4 WOI33848.1    
 INS88_00350   Trueperella pecoris 15A0121 QOR46571.1    
 INS88_00825 (fragment)   Trueperella pecoris 15A0121 QOR45814.1    
 INS88_00830 (fragment)   Trueperella pecoris 15A0121 QOR45815.1    
 HLG82_09485   Trueperella pecoris 19M2397 QOQ39948.1    
 HLG82_09005   Trueperella pecoris 19M2397 QOQ39561.1    
 INS90_00355   Trueperella pecoris 19OD0592 QOR47802.1    
 INS90_00860   Trueperella pecoris 19OD0592 QOR47896.1    
 QEV13_07860   Trueperella pyogenes 09KM1269 WHU60558.1    
 QEV13_06530   Trueperella pyogenes 09KM1269 WHU60305.1    
 QEV21_07595   Trueperella pyogenes 13KM1326 WHU58553.1    
 QEV10_02585   Trueperella pyogenes 13OD0707 WHU57599.1    
 QEV10_03870   Trueperella pyogenes 13OD0707 WHU57843.1    
 AN946_03715   Trueperella pyogenes 2012CQ-ZSH ALD74700.1    
 AN946_02430   Trueperella pyogenes 2012CQ-ZSH ALD74670.1    
 M5C92_00395   Trueperella pyogenes 22/KM0800 UVJ59835.1    
 DBV13_07945   Trueperella pyogenes Arash114 AWA43941.1    
 K5713_00415   Trueperella pyogenes EMSSI21 UVJ53829.1    
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