| Known Activities | α-galactosidase (EC 3.2.1.22); α-N-acetylgalactosaminidase (EC 3.2.1.49); stachyose synthase (EC 2.4.1.67); raffinose synthase (EC 2.4.1.82) |
|---|---|
| Mechanism | Retaining |
| Clan | GH-D |
| 3D Structure Status | ( β / α ) 8 |
| Catalytic Nucleophile/Base | Asp (experimental) |
| Catalytic Proton Donor | Asp (experimental) |
| Note | Mechanistic commonality with family GH27 demonstrated by Comfort et al. (2007) Biochemistry, 46: 3319-3330 (PMID: 17323919) |
| External resources | CAZypedia; InterPro; PRINTS; |
| Commercial Enzyme Provider(s) | MEGAZYME; |
| Statistics | GenBank accession (1001); Uniprot accession (559); PDB accession (6); 3D entries (6); cryst (2) |
| Bacteria | ||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | |
| α-galactosidase (AgaB;AgaB1) | 3.2.1.22 | Geobacillus stearothermophilus KVE39 | AAG49421.1 | Q934H7 | cryst | |
| α-galactosidase (AgaA;Aga1) | 3.2.1.22 | Geobacillus stearothermophilus KVE39 | AAG49420.1 | Q9ALJ4 | cryst | |
| α-galactosidase (MelA;Aga;LBA1438) | 3.2.1.22 | Lactobacillus acidophilus NCFM | AAV43263.1 | 2XN0[A,B] 2XN1[A,B,C,D] 2XN2[A] |
||
| LVIS_1758 (LbR11) | Lactobacillus brevis ATCC 367 | ABJ64825.1 | Q03PP7 | 3MI6[A,B,C,D] | ||
| α-galactosidase/sucrose kinase (AgaSK;RUGNEv3_61222) | 3.2.1.22 | Ruminococcus gnavus E1 | CCA61959.1 | 2YFO[A] | ||
| α-galactosidase (GalA;Tm1192) (Gal36) | 3.2.1.22 | Thermotoga maritima MSB8 | AAD36267.1 AAM56791.1 CAA04514.1 CAD29026.1 CAH68692.1 CAT81453.1 NP_228997.1 |
O33835 | 1ZY9[A] | |