Activities in Family	Exo-α-sialidase (EC 3.2.1.18);
Mechanism	Retaining e
Clan	GH-E
3D Structure Status	6-fold β-propeller
Catalytic Nucleophile/Base	Tyr+Glu
Catalytic Proton Donor	Not known
External resources	CAZypedia; HOMSTRAD; ProteinSpotlight;
Statistics	GenBank accession (139011); Uniprot accession (46); PDB accession (250); 3D entries (58); cryst (0)

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Viruses
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
neuraminidase (NA)		Influenza A virus A/India/JIPMER-NA-43/2017	QED88334.1
neuraminidase (NA)		Influenza A virus A/India/JIPMER-NA-50/2017	QED88335.1
neuraminidase (NA)		Influenza A virus A/India/JIPMER-NA-53/2017	QED88338.1
neuraminidase (NA)		Influenza A virus A/India/JIPMER-NA-66/2017	QED88339.1
neuraminidase (NA)		Influenza A virus A/India/JIPMER-NA-72/2017	QED88340.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB189/2019	QNT11978.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB208/2019	QNT11979.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB233/2019	QNT11980.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB240/2019	QNT11981.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB245/2019	QNT11982.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB249/2019	QNT11983.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB250/2019	QNT11984.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB254/2019	QNT11985.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB255/2019	QNT11986.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB257/2019	QNT11987.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB289/2019	QNT11988.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB294/2019	QNT11989.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB309/2019	QNT11990.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB310/2019	QNT11991.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB322/2019	QNT11992.1
neuraminidase (NA)		Influenza A virus A/India/KeralaRGCB477/2019	QNT11993.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_31933/2022	WNH42948.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_36991/2023	WNH42947.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_37314/2023	WNH42945.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_39197/2023	WNH42946.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_A69781/2021	UVJ70159.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_A77658/2021	UVJ70160.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_A81372/2021	UVJ70161.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_A84450/2021	UVJ70162.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_A84470/2021	UVJ70163.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_A85761/2021	UVJ70164.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_F100553/2022	WBO06459.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_F15009/2022	WBO06460.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_F15697/2022	WBO06465.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_F9988/2022	WBO06464.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_SF12/2020	WBO06455.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_SF132/2020	WBO06457.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_SF39/2020	WBO06462.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_SF75/2020	WBO06456.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_SF76/2020	WBO06461.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_SF80/2022	WBO06463.1
neuraminidase (NA)		Influenza A virus A/India/PGIMER_SF838/2020	WBO06458.1
neuraminidase (NA)		Influenza A virus A/India/Pun-1842249/2018	AXG72476.1
neuraminidase (NA)		Influenza A virus A/India/Pun-1843188/2018	AXG72477.1
neuraminidase (NA)		Influenza A virus A/India/Pun-1843196/2018	AXG72478.1
neuraminidase (NA)		Influenza A virus A/India/Pun-1844316/2018	AXG72479.1
neuraminidase (NA)		Influenza A virus A/India/Pun-1844612/2018	AXG21635.1
neuraminidase (NA)		Influenza A virus A/India/SARI-4571/2021	UDV79402.1
neuraminidase (NA)		Influenza A virus A/India/SF 382/2019	UBP77631.1
neuraminidase (NA)		Influenza A virus A/India/SF 408/2019	UBP77632.1
neuraminidase (NA)		Influenza A virus A/India/SF 426/2019	UBP77633.1
neuraminidase (NA)		Influenza A virus A/India/SF 439/2019	UBP77634.1
neuraminidase (NA)		Influenza A virus A/India/SF 590/2019	UBP77635.1
neuraminidase (NA)		Influenza A virus A/India/SF 696/2019	UBP77636.1
neuraminidase (NA)		Influenza A virus A/India/SF 769/2019	UBP77637.1
neuraminidase (NA)		Influenza A virus A/India/SF 775/2019	UBP77638.1
neuraminidase (NA)		Influenza A virus A/India/SF 805/2019	UBP77639.1
neuraminidase (NA)		Influenza A virus A/India/SF 900/2019	UBP77640.1
neuraminidase (NA)		Influenza A virus A/India/Sri-1844658/2018	AXG72462.1 AXG72467.1
neuraminidase (NA)		Influenza A virus A/India/Sri-1844661/2018	AXG72463.1 AXG72468.1
neuraminidase (NA)		Influenza A virus A/India/Sri-1844662/2018	AXG72464.1 AXG72469.1
neuraminidase (NA)		Influenza A virus A/India/Sri-1844666/2018	AXG72460.1 AXG72465.1
neuraminidase (NA)		Influenza A virus A/India/Sri-1844667/2018	AXG72461.1 AXG72466.1
neuraminidase (NA)		Influenza A virus A/India/TCM2581/2019	QBP33429.1
neuraminidase (NA)		Influenza A virus A/Indiana/01/2018	AVP04048.1
neuraminidase (NA)		Influenza A virus A/Indiana/01/2019	QBM03621.1
neuraminidase (NA)		Influenza A virus A/Indiana/01/2020	QIQ44841.1
neuraminidase (NA)		Influenza A virus A/Indiana/01/2022	UPP05569.1
neuraminidase (NA)		Influenza A virus A/Indiana/01/2023	WJN09490.1
neuraminidase (NA)		Influenza A virus A/Indiana/01/2023	WJN09478.1
neuraminidase (NA)		Influenza A virus A/Indiana/02/2018	AVP03618.1
neuraminidase (NA)		Influenza A virus A/Indiana/02/2019	QBM03632.1
neuraminidase (NA)		Influenza A virus A/Indiana/02/2020	QIQ44853.1 QIZ32356.1 QJT24457.1 QKG62260.1 QLF80321.1
neuraminidase (NA)		Influenza A virus A/Indiana/02/2020	QKG62267.1
neuraminidase (NA)		Influenza A virus A/Indiana/02/2021	ULD17881.1
neuraminidase (NA)		Influenza A virus A/Indiana/02/2021	UYL15469.1
neuraminidase (NA)		Influenza A virus A/Indiana/02/2021	UYL66728.1
neuraminidase (NA)		Influenza A virus A/Indiana/02/2022	UPP05593.1
neuraminidase (NA)		Influenza A virus A/Indiana/03/2018	AVP03627.1
neuraminidase (NA)		Influenza A virus A/Indiana/03/2019	QBP38546.1 QCW14351.1
neuraminidase (NA)		Influenza A virus A/Indiana/03/2020	QIV14350.1
neuraminidase (NA)		Influenza A virus A/Indiana/03/2021	ULD17893.1
neuraminidase (NA)		Influenza A virus A/Indiana/03/2021	UYL15481.1
neuraminidase (NA)		Influenza A virus A/Indiana/03/2021	UYL66740.1
neuraminidase (NA)		Influenza A virus A/Indiana/03/2022	UPP05617.1
neuraminidase (NA)		Influenza A virus A/Indiana/04/2018	AVP04060.1
neuraminidase (NA)		Influenza A virus A/Indiana/04/2019	QBP37800.1
neuraminidase (NA)		Influenza A virus A/Indiana/04/2020	QIV14361.1
neuraminidase (NA)		Influenza A virus A/Indiana/04/2021	ULD17905.1 ULE38992.1
neuraminidase (NA)		Influenza A virus A/Indiana/04/2021	UYL82170.1
neuraminidase (NA)		Influenza A virus A/Indiana/04/2021	UYL67835.1
neuraminidase (NA)		Influenza A virus A/Indiana/04/2022	UXG52572.1
neuraminidase (NA)		Influenza A virus A/Indiana/04/2022	UXG51541.1
neuraminidase (NA)		Influenza A virus A/Indiana/05/2018	AVR40955.1
neuraminidase (NA)		Influenza A virus A/Indiana/05/2019	QBP38558.1 QCW14363.1
neuraminidase (NA)		Influenza A virus A/Indiana/05/2020	QIZ32367.1
neuraminidase (NA)		Influenza A virus A/Indiana/05/2021	ULD17917.1 ULE39004.1
neuraminidase (NA)		Influenza A virus A/Indiana/05/2021	UYL82182.1
neuraminidase (NA)		Influenza A virus A/Indiana/05/2021	UYL67847.1
neuraminidase (NA)		Influenza A virus A/Indiana/05/2022	UXG51553.1
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