Activities in Family	Exo-α-sialidase (EC 3.2.1.18);
Mechanism	Retaining e
Clan	GH-E
3D Structure Status	6-fold β-propeller
Catalytic Nucleophile/Base	Tyr+Glu
Catalytic Proton Donor	Not known
External resources	CAZypedia; HOMSTRAD; ProteinSpotlight;
Statistics	GenBank accession (139011); Uniprot accession (46); PDB accession (250); 3D entries (58); cryst (0)

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Viruses
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
neuraminidase (NA)		Influenza A virus A/Gallus gallus/Belgium/4327/2019	QIL88232.1
neuraminidase (NA)		Influenza A virus A/Gallus gallus/Belgium/4464/2019	QGW67207.1
neuraminidase (NA)		Influenza A virus A/Gallus gallus/Belgium/4492/2019	QCU55423.1
neuraminidase (NA)		Influenza A virus A/Gallus gallus/Belgium/4768/2019	QGW67209.1
neuraminidase (NA)		Influenza A virus A/Gallus gallus/Belgium/5227/2019	QGW67210.1
neuraminidase (NA)		Influenza A virus A/Gallus gallus/Belgium/5597/2019	QGW67211.1
neuraminidase (NA)		Influenza A virus A/Gallus gallus/Belgium/5680/2019	QGW67212.1
neuraminidase (NA)		Influenza A virus A/Gallus gallus/Belgium/5839/2019	QGW67213.1
neuraminidase (NA)		Influenza A virus A/Gallus gallus/Belgium/6079/2019	QGW67214.1
neuraminidase (NA)		Influenza A virus A/Gallus gallus/Belgium/609/2019	QCU55419.1
neuraminidase (NA)		Influenza A virus A/Gallus gallus/Belgium/6486/2019	QGW67215.1
neuraminidase (NA)		Influenza A virus A/Gallus gallus/Belgium/6519/2019	QGW67216.1
neuraminidase (NA)		Influenza A virus A/Gallus gallus/Belgium/6986/2019	QGW67217.1
neuraminidase (NA)		Influenza A virus A/garganey/Bangladesh/38920/2019	QIC52389.1
neuraminidase (NA)		Influenza A virus A/garganey/North-Kazakhstan/45/2018	QHI00890.1
neuraminidase (NA)		Influenza A virus A/Geese/Bangladesh/200O-GEES-1-2/2018	WBO06477.1
neuraminidase (NA)		Influenza A virus A/gentoo penguin/Ardley/P11A/2017	AXK59034.1
neuraminidase (NA)		Influenza A virus A/Georgia/01/2018	AVP06739.1
neuraminidase (NA)		Influenza A virus A/Georgia/01/2019	QBM03526.1
neuraminidase (NA)		Influenza A virus A/Georgia/01/2020	QMX87461.1
neuraminidase (NA)		Influenza A virus A/Georgia/01/2021	UJS42851.1
neuraminidase (NA)		Influenza A virus A/Georgia/01/2021	UYL15421.1
neuraminidase (NA)		Influenza A virus A/Georgia/01/2022	UYC48278.1
neuraminidase (NA)		Influenza A virus A/Georgia/01/2022	UYC48289.1
neuraminidase (NA)		Influenza A virus A/Georgia/02/2019	QBS21080.1
neuraminidase (NA)		Influenza A virus A/Georgia/02/2020	QIQ44257.1
neuraminidase (NA)		Influenza A virus A/Georgia/02/2021	UJS42863.1
neuraminidase (NA)		Influenza A virus A/Georgia/02/2021	UYL15433.1
neuraminidase (NA)		Influenza A virus A/Georgia/02/2022	UYC48099.1
neuraminidase (NA)		Influenza A virus A/Georgia/02/2022	UYC48111.1
neuraminidase (NA)		Influenza A virus A/Georgia/02/2023	WES71170.1
neuraminidase (NA)		Influenza A virus A/Georgia/03/2018	AVR41601.1
neuraminidase (NA)		Influenza A virus A/Georgia/03/2019	QBM03533.1 QFO38697.1
neuraminidase (NA)		Influenza A virus A/Georgia/03/2020	QJA11065.1
neuraminidase (NA)		Influenza A virus A/Georgia/03/2021	ULD17809.1 ULE38920.1
neuraminidase (NA)		Influenza A virus A/Georgia/03/2021	UYL65570.1
neuraminidase (NA)		Influenza A virus A/Georgia/03/2021	UYL67775.1
neuraminidase (NA)		Influenza A virus A/Georgia/03/2022	UYC48123.1
neuraminidase (NA)		Influenza A virus A/Georgia/03/2022	UYC48135.1
neuraminidase (NA)		Influenza A virus A/Georgia/04/2018	AVR42077.1 AXY84403.1
neuraminidase (NA)		Influenza A virus A/Georgia/04/2019	QBS21092.1 QCG84375.1
neuraminidase (NA)		Influenza A virus A/Georgia/04/2020	QIZ31763.1
neuraminidase (NA)		Influenza A virus A/Georgia/04/2021	ULD17821.1 ULE38932.1
neuraminidase (NA)		Influenza A virus A/Georgia/04/2021	UYL67787.1
neuraminidase (NA)		Influenza A virus A/Georgia/04/2021	UYL65582.1
neuraminidase (NA)		Influenza A virus A/Georgia/04/2022	UYC48147.1
neuraminidase (NA)		Influenza A virus A/Georgia/04/2022	UYC48159.1
neuraminidase (NA)		Influenza A virus A/Georgia/05/2018	AVR40350.1
neuraminidase (NA)		Influenza A virus A/Georgia/05/2019	QBP38135.1 QCG84387.1
neuraminidase (NA)		Influenza A virus A/Georgia/05/2020	QIZ32228.1
neuraminidase (NA)		Influenza A virus A/Georgia/05/2021	ULD17833.1 ULE38944.1
neuraminidase (NA)		Influenza A virus A/Georgia/05/2021	UYL67799.1
neuraminidase (NA)		Influenza A virus A/Georgia/05/2021	UYL65594.1
neuraminidase (NA)		Influenza A virus A/Georgia/05/2022	UYC48300.1
neuraminidase (NA)		Influenza A virus A/Georgia/05/2022	UYC48311.1
neuraminidase (NA)		Influenza A virus A/Georgia/05/2023	WES71181.1
neuraminidase (NA)		Influenza A virus A/Georgia/06/2018	AVR40823.1
neuraminidase (NA)		Influenza A virus A/Georgia/06/2019	QBP38402.1 QCG83716.1
neuraminidase (NA)		Influenza A virus A/Georgia/06/2022	WBR45481.1
neuraminidase (NA)		Influenza A virus A/Georgia/06/2022	WBR45470.1
neuraminidase (NA)		Influenza A virus A/Georgia/06/2023	WES71192.1
neuraminidase (NA)		Influenza A virus A/Georgia/07/2018	AVR40834.1
neuraminidase (NA)		Influenza A virus A/Georgia/07/2019	QBP37734.1
neuraminidase (NA)		Influenza A virus A/Georgia/07/2022	WBO06873.1
neuraminidase (NA)		Influenza A virus A/Georgia/07/2022	WBO06885.1
neuraminidase (NA)		Influenza A virus A/Georgia/08/2018	AVR42089.1
neuraminidase (NA)		Influenza A virus A/Georgia/08/2019	QCW16611.1
neuraminidase (NA)		Influenza A virus A/Georgia/09/2018	AVX28225.1
neuraminidase (NA)		Influenza A virus A/Georgia/09/2019	QDX12251.1 QDQ44391.1
neuraminidase (NA)		Influenza A virus A/Georgia/09/2022	WBO06897.1
neuraminidase (NA)		Influenza A virus A/Georgia/09/2022	WBR45161.1
neuraminidase (NA)		Influenza A virus A/Georgia/10/2018	AVR42101.1
neuraminidase (NA)		Influenza A virus A/Georgia/10/2019	QDX12263.1
neuraminidase (NA)		Influenza A virus A/Georgia/11/2018	AVX28757.1
neuraminidase (NA)		Influenza A virus A/Georgia/11/2019	QCW17044.1
neuraminidase (NA)		Influenza A virus A/Georgia/12/2018	AXA18642.1 AYN08039.1
neuraminidase (NA)		Influenza A virus A/Georgia/12/2019	QDX12287.1
neuraminidase (NA)		Influenza A virus A/Georgia/12/2022	WBR45492.1
neuraminidase (NA)		Influenza A virus A/Georgia/12/2022	WBR45503.1
neuraminidase (NA)		Influenza A virus A/Georgia/12477/2021	UUB19761.1
neuraminidase (NA)		Influenza A virus A/Georgia/12478/2021	UUB19773.1
neuraminidase (NA)		Influenza A virus A/Georgia/12479/2021	UUB19785.1
neuraminidase (NA)		Influenza A virus A/Georgia/12480/2021	UUB19797.1
neuraminidase (NA)		Influenza A virus A/Georgia/12481/2021	UUB19687.1
neuraminidase (NA)		Influenza A virus A/Georgia/12482/2021	UUB19809.1
neuraminidase (NA)		Influenza A virus A/Georgia/12483/2021	UUB19821.1
neuraminidase (NA)		Influenza A virus A/Georgia/12484/2021	UUB19833.1
neuraminidase (NA)		Influenza A virus A/Georgia/12485/2021	UUB19845.1
neuraminidase (NA)		Influenza A virus A/Georgia/12487/2021	UUB19688.1
neuraminidase (NA)		Influenza A virus A/Georgia/12488/2021	UUB19857.1
neuraminidase (NA)		Influenza A virus A/Georgia/12489/2021	UUB19869.1
neuraminidase (NA)		Influenza A virus A/Georgia/12490/2021	UUB19881.1
neuraminidase (NA)		Influenza A virus A/Georgia/12491/2021	UUB19893.1
neuraminidase (NA)		Influenza A virus A/Georgia/12492/2021	UUB19905.1
neuraminidase (NA)		Influenza A virus A/Georgia/12493/2021	UUB19917.1
neuraminidase (NA)		Influenza A virus A/Georgia/12494/2021	UUB19689.1
neuraminidase (NA)		Influenza A virus A/Georgia/12532/2021	UUB19145.1
neuraminidase (NA)		Influenza A virus A/Georgia/12533/2021	UUB19157.1
neuraminidase (NA)		Influenza A virus A/Georgia/12534/2021	UUB19169.1
neuraminidase (NA)		Influenza A virus A/Georgia/12535/2021	UUB19181.1
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