Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase (EC 3.2.1.-); anhydrosialidase (EC 4.2.2.15); 3-deoxy-D-manno-octulosonic-acid hydrolase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (3547); Uniprot accession (686); PDB accession (144); 3D entries (19); cryst (0)
All (3289) Archaea (1) Bacteria (2885) Eukaryota (371) Viruses (32) Structure (19) Characterized (96)
Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 sialidase (Orf1)   Avirulent turkey hemorrhagic enteritis virus VIRGINIA AAX51169.2 Q2TLE1  
 EhV145_00535   Emiliania huxleyi virus 145 EhV-145 AHA55084.1    
 EhV164_00500   Emiliania huxleyi virus 164 EhV-164 AHA56087.1    
 ENVG_00100   Emiliania huxleyi virus 84 AEO97996.1    
 EOVG_00151   Emiliania huxleyi virus 88 AEP15088.1    
 ORF   Emiliania huxleyi virus 99B1 CAZ69785.1 D2TEV5  
 EhV455   Emiliania huxleyi virus sp. 86 CAI65882.1    
 sialidase 3.2.1.18 Frog adenovirus 1 AAF86921.1
NP_062432.1
Q9III6  
 HCTV5_112   Halovirus HCTV-5 AGM11720.1    
 sialidase   Raptor siadenovirus A AEC32095.1    
 SP029_00952   Salmonella phage FSL SP-029 AGF89170.1    
 SP063_01027   Salmonella phage FSL SP-063 AGF88656.1    
 sialidase   Skua siadenovirus A ADP30811.1    
 ORF1, partial   Turkey adenovirus 3 ARC53086.1    
 ORF1, partial   Turkey adenovirus 3 ARC53088.1    
 ORF1, partial   Turkey adenovirus 3 ARC53098.1    
 ORF1, partial   Turkey adenovirus 3 ARC53093.1    
 ORF1, partial   Turkey adenovirus 3 ARC53095.1    
 ORF1, partial   Turkey adenovirus 3 ARC53090.1    
 ORF1, partial   Turkey adenovirus 3 ARC53094.1    
 ORF1, partial   Turkey adenovirus 3 ARC53092.1    
 ORF1, partial   Turkey adenovirus 3 ARC53084.1    
 ORF1, partial   Turkey adenovirus 3 ARC53096.1    
 ORF1, partial   Turkey adenovirus 3 ARC53085.1    
 ORF1, partial   Turkey adenovirus 3 ARC53087.1    
 ORF1, partial   Turkey adenovirus 3 ARC53097.1    
 ORF1, partial   Turkey adenovirus 3 ARC53082.1    
 ORF1, partial   Turkey adenovirus 3 ARC53089.1    
 ORF1, partial   Turkey adenovirus 3 ARC53091.1    
 ORF1, partial   Turkey adenovirus 3 ARC53083.1    
 ORF1   Turkey adenovirus 3 AAC64539.1
NP_047379.1
Q9YUS1  
 ORF1   Turkey adenovirus 3 ABI23691.1
ABI23694.1
ABI23697.1
ABI23700.1
ABI23703.1
ABI23706.1
ABI23709.1
ABI23712.1
ABI23715.1
ABI23718.1
Q0GF95  
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