Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (4330); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (4018) Archaea (1) Bacteria (3601) Eukaryota (382) Viruses (34) Structure (19) Characterized (96)
Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 sialidase (Orf1)   Avirulent turkey hemorrhagic enteritis virus VIRGINIA AAX51169.2 Q2TLE1  
 EhV145_00535   Emiliania huxleyi virus 145 EhV-145 AHA55084.1    
 EhV164_00500   Emiliania huxleyi virus 164 EhV-164 AHA56087.1    
 ENVG_00100   Emiliania huxleyi virus 84 AEO97996.1    
 EOVG_00151   Emiliania huxleyi virus 88 AEP15088.1    
 ORF   Emiliania huxleyi virus 99B1 CAZ69785.1 D2TEV5  
 EhV455   Emiliania huxleyi virus sp. 86 CAI65882.1    
 tail fibers protein   Escherichia phage FEC14 ATW66765.1    
 sialidase 3.2.1.18 Frog adenovirus 1 AAF86921.1
NP_062432.1
Q9III6  
 HCTV5_112   Halovirus HCTV-5 AGM11720.1    
 ORF   Myoviridae environmental samples AVQ10309.1    
 sialidase   Raptor siadenovirus A AEC32095.1    
 SP029_00952   Salmonella phage FSL SP-029 AGF89170.1    
 SP063_01027   Salmonella phage FSL SP-063 AGF88656.1    
 sialidase   Skua siadenovirus A ADP30811.1    
 ORF1, partial   Turkey adenovirus 3 ARC53086.1    
 ORF1, partial   Turkey adenovirus 3 ARC53088.1    
 ORF1, partial   Turkey adenovirus 3 ARC53098.1    
 ORF1, partial   Turkey adenovirus 3 ARC53093.1    
 ORF1, partial   Turkey adenovirus 3 ARC53095.1    
 ORF1, partial   Turkey adenovirus 3 ARC53090.1    
 ORF1, partial   Turkey adenovirus 3 ARC53094.1    
 ORF1, partial   Turkey adenovirus 3 ARC53092.1    
 ORF1, partial   Turkey adenovirus 3 ARC53084.1    
 ORF1, partial   Turkey adenovirus 3 ARC53096.1    
 ORF1, partial   Turkey adenovirus 3 ARC53085.1    
 ORF1, partial   Turkey adenovirus 3 ARC53087.1    
 ORF1, partial   Turkey adenovirus 3 ARC53097.1    
 ORF1, partial   Turkey adenovirus 3 ARC53082.1    
 ORF1, partial   Turkey adenovirus 3 ARC53089.1    
 ORF1, partial   Turkey adenovirus 3 ARC53091.1    
 ORF1, partial   Turkey adenovirus 3 ARC53083.1    
 ORF1   Turkey adenovirus 3 AAC64539.1
NP_047379.1
Q9YUS1  
 ORF1   Turkey adenovirus 3 ABI23691.1
ABI23694.1
ABI23697.1
ABI23700.1
ABI23703.1
ABI23706.1
ABI23709.1
ABI23712.1
ABI23715.1
ABI23718.1
Q0GF95  
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