Glycoside Hydrolase Family 29

Activities in Familyα-L-fucosidase (EC 3.2.1.51); α-1,3/1,4-L-fucosidase (EC 3.2.1.111)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
External resourcesCAZypedia; PROSITE; SMART;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (2671); Uniprot accession (392); PDB accession (48); 3D entries (8); cryst (0)
All (2476) Archaea (20) Bacteria (2354) Eukaryota (101) unclassified (1) Structure (8) Characterized (33)
Bacteria
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 BACOVA_04357   Bacteroides ovatus ATCC 8483 EDO09977.1  
4ZRX[A] 1.59
 α-1,3/1,4-L-fucosidase / α-galactosidase (BT2192;BT_2192) 3.2.1.111 Bacteroides thetaiotaomicron VPI-5482 AAO77299.1
NP_811105.1
Q8A5P6
3EYP[A,B] 1.90
4OUE[A,B] β-D-Galp1S-(1-1)-<non_carb>
2.35
4OZO[A,B] β-D-Galp-(1-1)-<non_carb>
2.60
 α-L-fucosidase (Fuc2970;BtFuc2970;BT2970;BT_2970) 3.2.1.51 Bacteroides thetaiotaomicron VPI-5482 AAO78076.1
NP_811882.1
Q8A3I4
2WVS[A,B,C,D] β-L-Fucp2F
β-L-Fucp2F-(1-4)-ASP
2.19
2WVT[A,B] <carb_like_FHN>
1.80
2WVU[A,B,C,D] α-L-Fucp-(1-1)-<non_carb>
1.95
2WVV[A,B,C,D] 1.73
2XIB[A,B,C,D] <carb_like_DFU>
2.20
2XII[A,B] <carb_like_TA9>
1.80
4J27[A,B] 1.59
4J28[A,B] <carb_like_EAT>
1.73
4JFS[A,B] <carb_like_16Z>
2.00
4JFT[A,B] <carb_like_1KN>
2.10
4JFU[A,B] <carb_like_K80>
1.66
4JFV[A,B,C,D] <carb_like_H57>
1.88
4JFW[A,B,C,D] <carb_like_H58>
2.10
4JL1[A,B] <carb_like_LM5>
1.68
4JL2[A,B] <carb_like_LM5>
1.70
4PCS[A,B,C,D] <carb_like_2M7>
1.77
4PCT[A,B,C,D] <carb_like_H76>
2.10
4PEE[A,B,C,D] <carb_like_2OX>
1.95
4WSJ[A,B,C,D] <carb_like_3U3>
1.64
4WSK[A,B,C,D] <carb_like_3U2>
1.92
5HDR[A,B,C,D] 2.30
5I5R[A,B,C,D] 2.10
 BT3798   Bacteroides thetaiotaomicron VPI-5482 AAO78903.1
NP_812709.1
Q8A169
3GZA[A,B] 1.60
 α-1,3/1,4-L-fucosidase (BiAfcB;Blon_2336) 3.2.1.51
3.2.1.111
Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ53394.1 B7GNN8
3MO4[A,B] 1.90
3UES[A,B] <carb_like_DFU>
1.60
3UET[A,B] α-L-Fucp-(1-4)[β-D-Galp-(1-3)]-β-D-GlcpNAc
2.10
 α-L-fucosidase (Tm?Fuc;TM0306;Tmari_0304) 3.2.1.51 Thermotoga maritima MSB8 AAD35394.1
AGL49230.1
AHD17930.1
AKE28107.1
NP_228118.1
Q9WYE2
1HL8[A,B] 2.4
1HL9[A,B] β-L-Fucp2F-(1-4)-ASP
2.25
1ODU[A,B] β-L-Fucp
2.8
2WSP[A,B] α-L-Fucp-(1-2)-β-L-Fucp1N-(1-1)-<non_carb>
2.65
2ZWY[A,B] 2.75
2ZWZ[A,B] <carb_like_ZWZ>
2.36
2ZX5[A,B] <carb_like_ZX5>
2.65
2ZX6[A,B] <carb_like_ZX6>
2.42
2ZX7[A,B] <carb_like_ZX7>
2.48
2ZX8[A,B] <carb_like_ZX8>
2.33
2ZX9[A,B] <carb_like_ZX9>
2.62
2ZXA[A,B] <carb_like_ZXA>
2.57
2ZXB[A,B] <carb_like_ZXB>
2.61
2ZXD[A,B] <carb_like_ZXD>
2.15
Eukaryota
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 α-L-fucosidase (Fco1;FgFCO1;fg11254) 3.2.1.51 Fusarium graminearum PH-1 AFR68935.1
CEF87037.1
 
4NI3[A,B] 1.40
4PSP[A,B] 1.56
4PSR[A,B] β-L-Fucp
1.38
unclassified
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 GH29_0940 (partial)   unidentified    
5K9H[A] 2.03
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