Glycoside Hydrolase Family 23

Activities in FamilyChitinase (EC 3.2.1.14);
Lysozyme (EC 3.2.1.17);
Peptidoglycan lytic transglycosylase / peptidoglycan lyase (EC 4.2.2.29);
Mechanism Unknown e
3D Structure Statuslysozyme fold
Catalytic Nucleophile/BaseNot known
Catalytic Proton DonorGlu
NoteCorresponds to family 1 of the peptidoglycan lytic transglycosylases described by N.T. Blackburn and A.J. Clarke (2001) J. Mol. Evol. 52, 78-84; Note that 'peptidoglycan lytic transglycosylases' cleave peptidoglycan without intervention of a water molecule.
External resourcesCAZypedia; PRINTS;
Statistics GenBank accession (128573); Uniprot accession (60); PDB accession (91); 3D entries (22); cryst (0)
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Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CES85_0072   [Ochrobactrum] quorumnocens A44 ASV86567.1    
 CES85_0681   [Ochrobactrum] quorumnocens A44 ASV87467.1    
 CES85_1581   [Ochrobactrum] quorumnocens A44 ASV86938.1    
 transglycosylase SLT domain protein   uncultured Mediterranean phage uvMED BAR29454.1    
 transglycosylase SLT domain protein   uncultured Mediterranean phage uvMED BAR29438.1    
 transglycosylase SLT domain protein   uncultured Mediterranean phage uvMED BAR29443.1    
 transglycosylase SLT domain protein   uncultured Mediterranean phage uvMED BAR29446.1    
 transglycosylase SLT domain protein   uncultured Mediterranean phage uvMED BAR29450.1    
 protein of unknown function   uncultured Mediterranean phage uvMED BAQ89358.1    
 7S12_32   uncultured phage ASN71345.1    
 3S10_33   uncultured phage ASN71121.1    
 8AX11_15   uncultured phage ASN70338.1    
 7F8_15   uncultured phage ASN70397.1    
 9F3_32   uncultured phage ASN71392.1    
 7AX1_185   uncultured phage ASN67819.1    
 7F10_32   uncultured phage ASN71019.1    
 7AX5_32   uncultured phage ASN71290.1    
 8S5_32   uncultured phage ASN71928.1    
 8F1_33   uncultured phage ASN71895.1    
 7AX1_43   uncultured phage ASN67868.1    
 7AX4_49   uncultured phage ASN69689.1    
 7AX3_42   uncultured phage ASN68781.1    
 8AX6_3   uncultured phage ASN71830.1    
 tape measure domain protein   uncultured phage BBG57832.1    
 ORF   Vibrio phage 2 TSL-2019 QAU04218.1    
 endolysin   Vibrio phage 27Ua.3 UZM04606.1    
 endolysin   Vibrio phage 31Fb.4 UZM04664.1    
 endolysin   Vibrio phage 33Fb.4 WAG58472.1    
 ORF   Vibrio phage 5 TSL-2019 QCW23142.1    
 endolysin   Vibrio phage F23s1 UCW44047.1    
 OPA17_52   Vibrio phage OPA17 WAY16726.1    
 OTA22_54   Vibrio phage OTA22 UGC97207.1    
 PG288_54   Vibrio phage PG288 WGL39734.1    
 ORF   Vibrio phage phiKT1019 UPT53971.1    
 ORF   Vibrio phage phiKT1028 UVD32195.1    
 pVa21_165   Vibrio phage pVa-21 AQT28106.1    
 pVa21_134   Vibrio phage pVa-21 AQT28075.1    
 protein containing transglycosylase domain   Vibrio phage R01 AXH68421.1    
 SSP002_052 (fragment)   Vibrio phage SSP002 AFE86379.1    
 membrane-bound lytic murein transglycosylase (Mltf10) (fragment)   Vibrio phage ST1 QGH74566.1    
 ORF   Vibrio phage USC-1 QDH47585.1    
 vBValSR12Z_52   Vibrio phage vB_ValS_R12Z WVW36952.1    
 internal virion protein D   Vibrio phage vB_VpaP_G1 QYW05823.1    
 HCMJ_52   Vibrio phage vB_VpaS_HCMJ QEP53420.1    
 KF3_015   Vibrio phage vB_VpaS_KF3 ATI19131.1    
 KF4_049   Vibrio phage vB_VpaS_KF4 ATI19262.1    
 KF5_051   Vibrio phage vB_VpaS_KF5 ATI19361.1    
 KF6_047   Vibrio phage vB_VpaS_KF6 ATI19455.1    
 MAR10_052   Vibrio phage vB_VpaS_MAR10 AFV81285.1    
 endolysin   Vibrio phage vB_VpaS_SD2 WWQ02168.1    
 protein containing transglycosylase domain   Vibrio phage vB_VpS_C2 QYW05948.1    
 protein containing transglycosylase domain   Vibrio phage vB_VpS_CC6 UTQ72783.1    
 membrane-bound lytic murein transglycosylase   Vibrio phage VP06 AVI05148.1    
 endolysin   Vibrio phage VpP1 MP WVX90480.1    
 VPy01_42   Vibrio phage VPy01 WJZ44428.1    
 VVP001_051   Vibrio phage VVP001 AUM58751.1    
 pwc_35   Weissella phage PWc ARQ94569.1    
 ORF   Xanthomonas citri phage CP2 BAM66446.1    
 10KY502B_gene0058   Xanthomonas phage 10KY502B WGH28258.1    
 ORF   Xanthomonas phage Alcala QTZ82592.1    
 ORF   Xanthomonas phage Bolivar QTZ82420.1    
 ORF   Xanthomonas phage Carpasina AWD92420.1    
 ORF   Xanthomonas phage Fontebon QTZ82645.1    
 XccvBFoX6_gp27   Xanthomonas phage FoX6 QJB22085.1    
 XccvBFoX7_gp27   Xanthomonas phage FoX7 QJB22184.1    
 transglycosylase SLT domain-containing protein   Xanthomonas phage JGB6 WEU67297.1    
 ORF   Xanthomonas phage JUN5 UEW68332.1    
 Laurelin_BL50047   Xanthomonas phage Laurelin URA07100.1    
 ORF   Xanthomonas phage MET23-P3 UEW68395.1    
 ORF   Xanthomonas phage Olaya QTZ82418.1    
 ORF   Xanthomonas phage RTH11 WJJ55171.1    
 ORF   Xanthomonas phage Sopo CAA2393668.1    
 ORF   Xanthomonas phage Soumapaz QTZ82685.1    
 ORF   Xanthomonas phage Tabio CAA2393596.1    
 ORF   Xanthomonas phage Tenjo CAA2409782.1    
 ORF   Xanthomonas phage Usaquen QTZ82535.1    
 LUCX_3   Xanthomonas phage vB_XciM_LucasX QVD49073.1    
 Xoosp14_172   Xanthomonas phage Xoo-sp14 QNR51863.1    
 ORF   Xylella phage Usme CAA2366763.1    
 ORF   Yersinia phage Berlin CAJ70686.1    
 fHeYen301_48   Yersinia phage fHe-Yen3-01 APU00381.1    
 fHeYen902_199   Yersinia phage fHe-Yen9-02 WOL24545.1    
 BN109_046 (G46)   Yersinia phage phi80-18 CCI88882.1
CCI88885.2
   
 internal virion protein   Yersinia phage phiA1122 AAP20539.1
NP_848303.1
   
 ORF   Yersinia phage phiR1-37 CCE26107.1    
 BN110_004 (G004)   Yersinia phage phiR8-01 CCI88385.1
CCI88423.2
   
 phiYe-F10_00041   Yersinia phage phiYe-F10 AKQ06800.1    
 internal virion protein D   Yersinia phage phiYeO3-12 CAB63637.1
NP_052116.1
   
 ORF069   Yersinia phage PYps16N QQO91242.1    
 ORF070   Yersinia phage PYps16T QQO91327.1    
 ORF066   Yersinia phage PYps23T QQO90985.1    
 ORF070   Yersinia phage PYps3T QQO91072.1    
 ORF011   Yersinia phage PYps49T QQO91353.1    
 ORF071   Yersinia phage PYps4T QQO91158.1    
 PYPS50_008   Yersinia phage PYPS50 AZF87539.1    
 PYps50T_008   Yersinia phage PYps50T QQM13699.1    
 R_43   Yersinia phage R AGB07362.1    
 internal virion protein D   Yersinia phage vB_YenP_AP10 ALK86968.1    
 vBYenPAB5_0039   Yersinia phage vB_YenP_AP5 AIM40382.1    
 ORF   Yersinia phage vB_YenP_ISAO8 AKQ07700.1    
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