Glycoside Hydrolase Family 18

Activities in FamilyNod factor hydrolase (EC 3.2.1.-);
Chitin exo-β-1,4-N-acetylglucosaminidase (EC 3.2.1.-);
Di-N-acetylchitobiase / reducing-end exo-hexosaminidase (EC 3.2.1.-);
Peptidoglycan endo-β-1,4-N-acetylglucosaminidase (EC 3.2.1.-);
Chitosanase (EC 3.2.1.132);
Chitinase (EC 3.2.1.14);
Chitin exo-β-1,4-N-acetylglucobiosaminidase (EC 3.2.1.200);
[reducing end] exo-chitinase (EC 3.2.1.201);
β-N-acetylhexosaminidase (EC 3.2.1.52);
Mannosyl-glycoprotein endo-β-N-acetylglucosaminidase (EC 3.2.1.96);
Mechanism Retaining e
ClanGH-K
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu (experimental)
NoteContains chitinases of classes III and V. Contains non-catalytic proteins such as xylanase inhibitor; concanavalin B; narbonin
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (42170); Uniprot accession (503); PDB accession (428); 3D entries (111); cryst (2)
| 1 | ... | 136 | 137 | 138 | 139 | 140 | 141 | 142 | 143 | 144 | ... | 332 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 GAU_3141   Gemmatimonas aurantiaca T-27 BAH40183.1    
 GAU_3290   Gemmatimonas aurantiaca T-27 BAH40332.1    
 HKW67_18900   Gemmatimonas groenlandica TET16 QJR37430.1    
 GEMMAAP_05725   Gemmatimonas phototrophica AP64 AMW04476.1    
 GEMMAAP_16805   Gemmatimonas phototrophica AP64 AMW06000.1    
 J421_0107   Gemmatirosa kalamazoonensis KBS708 AHG87644.1    
 J421_0117   Gemmatirosa kalamazoonensis KBS708 AHG87654.1    
 J421_0119   Gemmatirosa kalamazoonensis KBS708 AHG87656.1    
 J421_0120   Gemmatirosa kalamazoonensis KBS708 AHG87657.1    
 J421_0121   Gemmatirosa kalamazoonensis KBS708 AHG87658.1    
 J421_0118   Gemmatirosa kalamazoonensis KBS708 AHG87655.1    
 M493_02295   Geobacillus genomosp. 3 JF8 AGT30793.1    
 M493_00300   Geobacillus genomosp. 3 JF8 AGT30475.1    
 M493_12545   Geobacillus genomosp. 3 JF8 AGT32756.1    
 M493_10620   Geobacillus genomosp. 3 JF8 AGT32385.1
AGT32385.2
   
 GK0014   Geobacillus kaustophilus HTA426 BAD74299.1    
 GK2077   Geobacillus kaustophilus HTA426 BAD76362.1    
 GK2418   Geobacillus kaustophilus HTA426 BAD76703.1    
 E5Z46_08280   Geobacillus kaustophilus NBRC 102445 QCK82243.1    
 E5Z46_03080   Geobacillus kaustophilus NBRC 102445 QCK81428.1    
 E5Z46_15860   Geobacillus kaustophilus NBRC 102445 QCK83539.1    
 RA957_12625   Geobacillus kaustophilus T-1 WMJ19059.1    
 RA957_00095   Geobacillus kaustophilus T-1 WMJ20045.1    
 GLN3_10275   Geobacillus lituanicus N-3 ASS87437.1    
 RA955_03565   Geobacillus proteiniphilus T-6 WMJ17206.1    
 RA955_07265   Geobacillus proteiniphilus T-6 WMJ18295.1    
 RA955_16205   Geobacillus proteiniphilus T-6 WMJ16173.1    
 GARCT_02398 (Yaah_2) (fragment)   Geobacillus sp. 12AMOR1 AKM19650.1    
 GARCT_00019 (Yaah_1)   Geobacillus sp. 12AMOR1 AKM17397.1    
 IC801_05385   Geobacillus sp. 44B QNU38671.1    
 IC801_11145   Geobacillus sp. 44B QNU36471.1    
 IC802_03395   Geobacillus sp. 44C QNU35030.1    
 IC802_08430   Geobacillus sp. 44C QNU35868.1    
 IC803_06525   Geobacillus sp. 46C-IIa QNU29173.1    
 IC803_17070   Geobacillus sp. 46C-IIa QNU27876.1    
 IC803_01560   Geobacillus sp. 46C-IIa QNU28294.1    
 IC803_04785   Geobacillus sp. 46C-IIa QNU28875.1    
 IC804_09875   Geobacillus sp. 47C-IIb QNU29894.1    
 IC804_11980   Geobacillus sp. 47C-IIb QNU30219.1    
 IC804_03965   Geobacillus sp. 47C-IIb QNU31934.1    
 GC56T3_1440   Geobacillus sp. C56-T3 ADI26453.1    
 GC56T3_1070   Geobacillus sp. C56-T3 ADI26112.1    
 GC56T3_0014   Geobacillus sp. C56-T3 ADI25088.1    
 GHH_c21270 (YdhD)   Geobacillus sp. GHH01 AGE22645.1    
 GHH_c24950 (Yaah2)   Geobacillus sp. GHH01 AGE23006.1    
 GHH_c00190 (Yaah1)   Geobacillus sp. GHH01 AGE20631.1    
 A0V43_15250   Geobacillus sp. JS12 AMQ22005.1    
 A0V43_08085   Geobacillus sp. JS12 AMQ22566.1    
 A0V43_09990   Geobacillus sp. JS12 AMQ21159.1    
 IB49_03895   Geobacillus sp. LC300 AKU25736.1    
 IB49_10240   Geobacillus sp. LC300 AKU26764.1    
 GWCH70_0017   Geobacillus sp. WCH70 ACS22959.1    
 GY4MC1_0016   Geobacillus sp. Y4.1MC1 ADP72872.1    
 GY4MC1_1150   Geobacillus sp. Y4.1MC1 ADP73962.1    
 GYMC52_2031   Geobacillus sp. Y412MC52 ADU94443.1    
 GYMC52_2443   Geobacillus sp. Y412MC52 ADU94825.1    
 GYMC52_0015   Geobacillus sp. Y412MC52 ADU92530.1    
 GYMC61_0014   Geobacillus sp. Y412MC61 ACX76714.1    
 GYMC61_2901   Geobacillus sp. Y412MC61 ACX79475.1    
 GYMC61_0223   Geobacillus sp. Y412MC61 ACX76921.1    
 GT50_09405   Geobacillus stearothermophilus 10 ALA70397.1    
 GT50_14805   Geobacillus stearothermophilus 10 ALA71288.1    
 GT50_17005   Geobacillus stearothermophilus 10 ALA71659.1    
 QSJ10_00095   Geobacillus stearothermophilus ATCC 12980 WJM12851.1    
 QSJ10_12405   Geobacillus stearothermophilus ATCC 12980 WJM12350.1    
 EPB69_11860   Geobacillus stearothermophilus B5 QHN49839.1    
 EPB69_00100   Geobacillus stearothermophilus B5 QHN47969.1    
 IMZ17_14725   Geobacillus stearothermophilus DG-1 QOR83793.1    
 IMZ17_12235   Geobacillus stearothermophilus DG-1 QOR83348.1    
 IMZ17_00100   Geobacillus stearothermophilus DG-1 QOR84341.1    
 GS458_2708   Geobacillus stearothermophilus DSM 458 ATA61144.1    
 GS458_2200   Geobacillus stearothermophilus DSM 458 ATA60641.1    
 GS458_0014   Geobacillus stearothermophilus DSM 458 ATA58478.1    
 QT235_00100   Geobacillus stearothermophilus EF60045 WJQ07192.1    
 QT236_00100   Geobacillus stearothermophilus EF60063 WJQ03802.1    
 QT236_11800   Geobacillus stearothermophilus EF60063 WJQ02723.1    
 QT237_00100   Geobacillus stearothermophilus EF60133 WJQ10670.1    
 QT237_12795   Geobacillus stearothermophilus EF60133 WJQ09607.1    
 QT238_05570   Geobacillus stearothermophilus EF60134 WJQ15052.1    
 QT238_00100   Geobacillus stearothermophilus EF60134 WJQ14101.1    
 QT238_07450   Geobacillus stearothermophilus EF60134 WJQ15378.1    
 chitinase (fragment)   Geobacillus stearothermophilus JM-1 AEO12133.1    
 chitinase (fragment)   Geobacillus stearothermophilus JW1 AEO12132.1    
 QT234_12575   Geobacillus stearothermophilus SJEF4-2 WJP99491.1    
 QT234_00100   Geobacillus stearothermophilus SJEF4-2 WJQ00401.1    
 HF500_02235   Geobacillus subterraneus CPW16 QIZ66238.1    
 HF500_14670   Geobacillus subterraneus CPW16 QIZ68338.1    
 HF500_04260   Geobacillus subterraneus CPW16 QIZ66565.1    
 HF500_13015   Geobacillus subterraneus CPW16 QIZ68054.1    
 GsuE55_04600   Geobacillus subterraneus E55-1 BBW95627.1    
 GsuE55_33450 (YdhD)   Geobacillus subterraneus E55-1 BBW98512.1    
 GsuE55_12680   Geobacillus subterraneus E55-1 BBW96435.1    
 GsuE55_29010 (YaaH)   Geobacillus subterraneus E55-1 BBW98068.1    
 GS3922_04060   Geobacillus subterraneus KCTC 3922 AMX82921.1    
 GS3922_13710   Geobacillus subterraneus KCTC 3922 AMX84614.1    
 GS3922_15670   Geobacillus subterraneus KCTC 3922 AMX84932.1    
 UM396_00100   Geobacillus subterraneus OXR-76 WPZ18440.1    
 UM396_12255   Geobacillus subterraneus OXR-76 WPZ17363.1    
 GT3921_01355   Geobacillus thermocatenulatus KCTC 3921 ASS97819.1    
 GT3921_07380   Geobacillus thermocatenulatus KCTC 3921 ASS98881.1    
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