Glycoside Hydrolase Family 13 / Subf 6

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (1207); Uniprot accession (175); PDB accession (13); 3D entries (3); cryst (0)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 maltohexaose-forming α-amylase (AmyM) 3.2.1.98 Corallococcus sp. EGB AII00648.1     6
 STHERM_c15980 3.2.1.1 Spirochaeta thermophila DSM 6192 ADN02538.1 E0RN69   6
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 α-amylase (AtAmy1;At4g25000) (apoplast) 3.2.1.1 Arabidopsis thaliana CAB36742.1
AAL38709.1
AAM51369.1
AAM64582.1
AEE84990.1
CAB79409.1
NP_567714.1
Q8LBS5
Q8VZ56
Q9SW26
  6
 α-amylase A 3.2.1.1 Avena fatua CAA09323.1 O81699   6
 α-amylase D 3.2.1.1 Avena fatua CAA09324.1 O81700   6
 α-amylase 3.2.1.1 Cuscuta reflexa AAA16513.1 Q42678   6
 α-amylase (Amy1;Amy32b) 3.2.1.1 Hordeum vulgare CAA28803.1
AAA32935.1
AAY44169.1
AAY44170.1
Q42504   6
 α-amylase 1 (Amy1;Amy1.1) 3.2.1.1 Hordeum vulgare AAA32929.1
AAA32927.1
P00693
Q40017
1HT6[A]
1P6W[A]
1RP8[A]
1RP9[A]
1RPK[A]
2QPS[A]
2QPU[A,B,C]
3BSG[A]
3BSH[A]
6
 α-amylase 2 (Amy2) 3.2.1.1 Hordeum vulgare CAA33298.1
AAA32925.1
AAA98790.1
P04063
Q40015
1AMY[A]
1AVA[A,B]
1BG9[A]
6
 α-amylase 6 3.2.1.1 Hordeum vulgare CAA33299.1
AAA32932.1
AAA98615.1
P04750
Q03651
  6
 α-amylase (Amy1;Amy) 3.2.1.1 Hordeum vulgare subsp. vulgare CAA72143.1 O04964   6
 α-amylase (MAmy) 3.2.1.1 Musa acuminata AAO11776.1
AAN01149.1
AFP87138.1
Q8GUR0
Q8LJQ6
  6
 α-amylase (Amy1.1;Amy1-1) 3.2.1.1 Oryza sativa AAA33885.1
AAN89206.1
P17654   6
 α-amylase 3.2.1.1 Oryza sativa   P27935   6
 α-amylase 3.2.1.1 Oryza sativa AAA33897.1     6
 α-amylase 3.2.1.1 Oryza sativa Indica Group CAA45903.1 A2YGY2
P27941
  6
 α-amylase 1A / I-1 (α-Amy7;RAmy1A;Amy1.1;AmyI-1;Os02g0765600) 3.2.1.1 Oryza sativa Japonica Group BAF10134.1
ACA50496.1
BAD17125.1
BAD17313.1
BAG95208.1
BAS81060.1
CAA34516.1
P17654
Q0DXA4
3WN6[A,B,C,D] 6
 α-amylase (RAmy3A;Os09g0457400) 3.2.1.1 Oryza sativa Japonica Group CAA39776.1
BAD38366.1
BAF25281.1
BAG94071.1
BAT08441.1
P27932
Q0J184
  6
 α-amylase 2A (RAmy2A;Amy2A;Os06g0713800) 3.2.1.1 Oryza sativa Japonica Group BAD54103.1
AAA33894.1
BAF20482.1
BAG94883.1
BAS99475.1
B7E3X5
Q0D9J1
  6
 α-amylase 3B/3C / II-5/6 (α-Amy6;AmyII-5;AmyII-6;RAmy3B/Ramy3C;Amy1.7;Os09g0457800) 3.2.1.1 Oryza sativa Japonica Group BAD38369.1
ALC78410.1
BAF25283.1
BAT08444.1
CAA39778.1
P27939
P27939
Q0J182
  6
 α-amylase 3.2.1.1 Phaseolus vulgaris BAA33879.1 Q9ZP43   6
 α-amylase (Amy1) 3.2.1.1 Solanum tuberosum AAA91884.1
ACV30014.1
ACZ26470.1
CAA01542.1
CAA01546.1
Q41442   6
 α-amylase 3.2.1.1 Triticum aestivum AAA34259.1
CAA29252.1
CAZ78894.1
P08117   6
 α-amylase 3.2.1.1 Vigna angularis BAC76729.1 Q7X9T1   6
 α-amylase 3.2.1.1 Vigna mungo CAA37217.1
CAA51734.1
P17859   6
 α-amylase (AMY) 3.2.1.1 Vigna radiata 1803517A     6
 α-amylase 3.2.1.1 Zea mays ACF88424.1
AAA50161.1
ABJ38332.1
ACW20097.1
B4G231
Q41770
  6
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 ORF 3.2.1.1 uncultured organism AGU10738.1     6
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