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Glycoside Hydrolase Family 13 / Subf 24

Activities in Sub Family[retaining] α-amylase (EC 3.2.1.1);
Mechanism Retaining a
ClanGH-H
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (1); Uniprot accession (51); PDB accession (85); 3D entries (5); cryst (0)
Summary
Download GH13_24 (240) Taxonomic display Structure (5) Characterized (25)
Eukaryota
Protein Name EC# OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
Subf
 α-amylase I (Amy I; Ef-Amy I) 3.2.1.1 Eisenia fetida BAV13234.1 A0A173N065
6M4K[A] 1.30
6M4L[A] 1.60
6M4M[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
 1.70
24
 α-amylase (Amy2A) (pancreatic) 3.2.1.1 Homo sapiens AAA51724.1
AAA51723.1
AAA51725.1
AAA52280.1
AAH07060.1
AAI46998.1
BAD97183.1
CAA30099.1
CAA30100.1
CAN87444.1
NP_000690.1		 P04746
P04746
P19961
Q53F26
1B2Y[A] α-D-6-deoxy-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-β-D-Glcp
 3.20
1BSI[A] 2.00
1CPU[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp
 2.00
1HNY[A] 1.80
1KB3[A] 2.10
1KBB[A] 1.90
1KBK[A] D-1-deoxy-GlcpNAc
 1.90
1KGU[A] 2.00
1KGW[A] 2.10
1KGX[A] 2.00
1U2Y[A] <carb_like_GOX>
 1.95
1U30[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-1)-<non_carb>
<carb_like_GOX>
 1.90
1U33[A] α-D-Glcp4Me-(1-4)-α-D-Glcp-(1-1)-<non_carb>
 1.95
1XCW[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp
 2.00
1XCX[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-6)-β-D-Glcp
 1.90
1XD0[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp
 2.00
1XD1[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-6)-β-D-Glcp
 2.20
1XGZ[A] 2.00
1XH0[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
 2.00
1XH1[A] 2.03
1XH2[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp
 2.20
2CPU[A] 2.00
2QMK[A] 2.30
2QV4[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N
 1.97
3BAI[A] 1.90
3BAJ[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp
 2.10
3BAK[A] 1.90
3BAW[A] 2.00
3BAX[A] 1.90
3BAY[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp
 1.99
3CPU[A] α-D-Glcp-(1-4)-α-D-Glcp
 2.00
3IJ7[A] α-D-Glcp4Me-(1-4)-α-D-Glcp-(1-4)-α-L-Idop5F-(1-4)-ASP
α-D-Glcp4Me-(1-4)-α-D-Glcp1F
 2.00
3IJ8[A] α-L-Idop5F-(1-4)-ASP
β-L-Idop1,5F
 1.43
3IJ9[A] α-D-Glcp-(1-4)-α-L-Idop5F-(1-4)-ASP
β-L-Idop1,5F
 1.85
3OLD[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp
 2.00
3OLE[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp
 1.55
3OLG[A] <acarbose_derivative>
unknown-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp
α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp
α-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp
 2.30
3OLI[A] <acarbose_derivative>
unknown-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
β-D-Glcp
 1.50
4GQQ[A] 1.35
4GQR[A] 1.20
4W93[A] β-D-Glcp-(1-2)-β-D-Glcp-(1-2)-α-L-Rhap-(1-1)-<non_carb>
 1.35
4X9Y[A] 1.07
5E0F[A] β-D-Glcp-(1-2)-α-L-Rhap-(1-1)-<non_carb>
 1.40
5EMY[A] 1.23
5KEZ[A] 1.83
5TD4[A] α-D-Glcp-(1-4)-α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
 2.30
5U3A[A] 0.95
5VA9[A,B] 2.55
6OBX[A] 1.30
6OCN[A] 1.15
6Z8L[A] α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp
 1.40
24
 α-amylase (salivary) (Amy1A;Amy1;HSA) 3.2.1.1 Homo sapiens AAH63129.1
AAA16183.1
AAA52279.1
AAA57345.1
AAA58368.1
AAH69347.1
AAH69463.1
AAH70302.1
AAH92444.1
AAI32986.1
AAI32988.1
AAI32996.1
AAI32998.1
AAI44453.1
BAF85030.1
NP_004029.2		 B7ZMD7
P04745
P0DTE7
P0DTE8
P0DUB6
Q6NSB3
1C8Q[A] 2.30
1JXJ[A] 1.99
1JXK[A] 1.90
1MFU[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp
<non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp
D-1-deoxy-Glcp
α-D-Glcp-(1-4)-D-1-deoxy-Glcp
 2.00
1MFV[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp
α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp
 2.00
1NM9[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp
α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
 2.10
1Q4N[X] 2.07
1SMD[A] 1.60
1XV8[A,B] 3.00
1Z32[X] β-D-Glcp-(1-4)-<non_carb>-(0-4)-D-1,6-deoxy-Glcp4N
 1.60
3BLK[A] α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp
 2.00
3BLP[X] α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp
 1.60
3DHP[A] α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp
 1.50
24
 α-amylase (partial) 3.2.1.1 Oryzias latipes   H2N0D4
3VM5[A] 2.85
24
 α-amylase (Ppa;PPA) (pancreatic) 3.2.1.1 Sus scrofa AAF02828.1 P00690
1BVN[P] 2.50
1DHK[A] 1.85
1HX0[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp-(1-1)-<non_carb>
 1.38
1JFH[A] α-D-Glcp-(1-4)-α-D-Glcp4S1S
α-D-Glcp4SMe-(1-4)-α-D-Glcp4S-(1-1)-methyl
 2.03
1KXQ[A] 1.60
1KXT[A] 2.00
1KXV[A] 1.60
1OSE[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-β-D-Glcp
β-D-Glcp
 2.30
1PIF[A] 2.30
1PIG[A] α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp
β-D-Glcp
β-D-Glcp-(1-4)-α-D-Glcp
 2.20
1PPI[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-<non_carb>-(0-4)-α-D-6-deoxy-Glcp4N-(1-4)-β-D-Glcp
 2.20
1UA3[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp
α-D-Glcp-(1-4)-β-D-Glcp
β-D-Glcp
 2.01
1VAH[A] 2.40
1WO2[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp
α-D-Glcp-(1-4)-β-D-Glcp
 2.01
3L2L[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
α-D-Glcp-(1-4)-α-D-Glcp-(1-4)[α-D-Glcp-(1-6)]-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
β-D-Glcp
 2.11
3L2M[A] 1.97
4X0N[A] 2.60
24
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