Activities in Sub Family	[retaining] α-amylase (EC 3.2.1.1);
Mechanism	Retaining a
Clan	GH-H
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	New: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resources	CAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (1); Uniprot accession (51); PDB accession (85); 3D entries (5); cryst (0)

Eukaryota
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D	Subf
α-amylase / allergen (Aca s 4)	3.2.1.1		Acarus siro	ABL09312.1	B0KZK1		24
α-amylase (Amy)	3.2.1.1	doi	Anguilla japonica	BAB85635.1	Q8QGW2		24
α-amylase B (AmyB;Amy)	3.2.1.1		Crassostrea gigas	AAL37207.1 ABB80387.1 ABB80388.1 ABR37235.1 ACC77978.1 ACC77979.1 ACC77980.1 CAD43101.1 CAD43102.1 CAD43103.1 CAD43104.1	A7YFC4 B2Y8J6 B2Y8J7 B2Y8J8 Q1A744 Q1A745 Q8I7E4 Q8I7E5 Q8I7E6 Q8I7E7 Q8WSG9		24
α-amylase (Der p 4;Derp4) (allergen)	3.2.1.1	pubmed	Dermatophagoides pteronyssinus	AAD38942.1	P49274 Q9Y197		24
α-amylase I (Amy I; Ef-Amy I)	3.2.1.1	pubmed	Eisenia fetida	BAV13234.1	A0A173N065	6M4K[A] 6M4L[A] 6M4M[A]	24
α-amylase II (Amy2; Amy II; Ef-Amy II)	3.2.1.1	pubmed	Eisenia fetida	BCN16346.1			24
α-amylase (Amy)	3.2.1.1	pubmed	Gallus gallus	AAC60246.1	Q98942		24
α-amylase 1 (AmyI;HdAmyI)	3.2.1.1		Haliotis discus discus	ABO26610.1	B6RB08		24
α-amylase (HdAmy58)	3.2.1.1		Haliotis discus hannai	BAM74656.1	L8AW48		24
α-amylase (Amy2A) (pancreatic)	3.2.1.1	pubmed	Homo sapiens	AAA51724.1 AAA51723.1 AAA51725.1 AAA52280.1 AAH07060.1 AAI46998.1 BAD97183.1 CAA30099.1 CAA30100.1 CAN87444.1 NP_000690.1	P04746 P04746 P19961 Q53F26	1B2Y[A] 1BSI[A] 1CPU[A] 1HNY[A] 1KB3[A] 1KBB[A] 1KBK[A] 1KGU[A] 1KGW[A] 1KGX[A] 1U2Y[A] 1U30[A] 1U33[A] 1XCW[A] 1XCX[A] 1XD0[A] 1XD1[A] 1XGZ[A] 1XH0[A] 1XH1[A] 1XH2[A] 2CPU[A] 2QMK[A] 2QV4[A] 3BAI[A] 3BAJ[A] 3BAK[A] 3BAW[A] 3BAX[A] 3BAY[A] 3CPU[A] 3IJ7[A] 3IJ8[A] 3IJ9[A] 3OLD[A] 3OLE[A] 3OLG[A] 3OLI[A] 4GQQ[A] 4GQR[A] 4W93[A] 4X9Y[A] 5E0F[A] 5EMY[A] 5KEZ[A] 5TD4[A] 5U3A[A] 5VA9[A,B] 6OBX[A] 6OCN[A] 6Z8L[A]	24
α-amylase (salivary) (Amy1A;Amy1;HSA)	3.2.1.1	pubmed	Homo sapiens	AAH63129.1 AAA16183.1 AAA52279.1 AAA57345.1 AAA58368.1 AAH69347.1 AAH69463.1 AAH70302.1 AAH92444.1 AAI32986.1 AAI32988.1 AAI32996.1 AAI32998.1 AAI44453.1 BAF85030.1 NP_004029.2	B7ZMD7 P04745 P0DTE7 P0DTE8 P0DUB6 Q6NSB3	1C8Q[A] 1JXJ[A] 1JXK[A] 1MFU[A] 1MFV[A] 1NM9[A] 1Q4N[X] 1SMD[A] 1XV8[A,B] 1Z32[X] 3BLK[A] 3BLP[X] 3DHP[A]	24
α-amylase	3.2.1.1	pubmed	Mus musculus	AAA37221.1 AAA37219.1 AAA37220.1 AAH04698.1 AAH09121.1 BAC26543.1 CAA24097.1 CAA24099.1 CAA24100.1 NP_031472.1	P00687 Q921Y7 Q99KE6		24
α-amylase	3.2.1.1	pubmed	Mus musculus	AAA37230.1 AAA37222.1 AAA37223.1 AAA37224.1 AAA37225.1 AAA37226.1 AAA37227.1 AAA37228.1 AAA37229.1 AAA37232.1 AAA37233.1 AAH94924.1 AAI00580.1 BAC37484.1 BAE21706.1 CAA24098.1 CAA26202.1 CAA26413.1 CAA26414.1 CAA26415.1 CAA26417.1 CAA26418.1 NP_033799.1	P00688 Q61297 Q61298 Q61299 Q8C5B4		24
α-amylase (partial)	3.2.1.1		Oryzias latipes		H2N0D4	3VM5[A]	24
α-amylase	3.2.1.1	pubmed	Pecten maximus	CAA68065.1	P91778		24
α-amylase 1	3.2.1.1	pubmed	Penaeus vannamei	CAA54524.1 AAR19061.1	Q26193 Q67C51		24
α-amylase (Amy)	3.2.1.1		Penaeus vannamei	CAB65553.1 AAR19062.1 CAD43060.1	Q67C50 Q9U0F6		24
α-amylase (Amy)	3.2.1.1		Penaeus vannamei	CAB65552.2	Q9U0F9		24
α-amylase (Amy2A)	3.2.1.1		Pseudopleuronectes americanus	AAF65827.1	Q9I9H6		24
α-amylase (Amy1)	3.2.1.1	pubmed	Rattus norvegicus	AAA40725.1 AAA40731.1 NP_113690.1	P00689		24
α-amylase (Amy1)	3.2.1.1		Rattus norvegicus	AAH88228.1 BAB39466.1	Q5I0L0 Q99N59		24
α-amylase (PA) (pancreatic)	3.2.1.1		Struthio camelus		P83053		24
α-amylase (Ppa;PPA) (pancreatic)	3.2.1.1		Sus scrofa	AAF02828.1	P00690	1BVN[P] 1DHK[A] 1HX0[A] 1JFH[A] 1KXQ[A] 1KXT[A] 1KXV[A] 1OSE[A] 1PIF[A] 1PIG[A] 1PPI[A] 1UA3[A] 1VAH[A] 1WO2[A] 3L2L[A] 3L2M[A] 4X0N[A]	24
amylase-1	3.2.1.1		Tetraodon nigroviridis	CAC87125.1	Q8UWE5		24
amylase-3	3.2.1.1		Tetraodon nigroviridis	CAC87127.1	Q8UWE3		24
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