Glycoside Hydrolase Family 13 / Subf 24

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (258); Uniprot accession (90); PDB accession (77); 3D entries (4); cryst (0)
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 α-amylase / allergen (Aca s 4) 3.2.1.1 Acarus siro ABL09312.1 B0KZK1   24
 α-amylase (Amy) 3.2.1.1 Anguilla japonica BAB85635.1 Q8QGW2   24
 α-amylase B (AmyB;Amy) 3.2.1.1 Crassostrea gigas AAL37207.1
ABB80387.1
ABB80388.1
ABR37235.1
ACC77978.1
ACC77979.1
ACC77980.1
CAD43101.1
CAD43102.1
CAD43103.1
CAD43104.1
Q8I7E4
Q8I7E5
Q8I7E6
Q8I7E7
Q8WSG9
  24
 α-amylase A (AmyA;Amy) 3.2.1.1 Crassostrea gigas AAL37183.1
ACB29736.1
ACC77975.1
ACC77976.1
ACC77977.1
CAA69658.1
CAD43095.1
CAD43096.1
CAD43097.1
CAD43098.1
CAD43099.1
CAD43100.1
O02622
Q8I080
Q8I0T4
Q8I7E8
Q8WSH2
  24
 α-amylase (Der p 4;Derp4) (allergen) 3.2.1.1 Dermatophagoides pteronyssinus AAD38942.1 P49274
Q9Y197
  24
 α-amylase (Eur m 4) (allergen) 3.2.1.1 Euroglyphus maynei AAD38943.1 Q9Y196   24
 α-amylase (Amy) 3.2.1.1 Gallus gallus AAC60246.1 Q98942   24
 α-amylase 1 (AmyI;HdAmyI) 3.2.1.1 Haliotis discus discus ABO26610.1 B6RB08   24
 α-amylase (HdAmy58) 3.2.1.1 Haliotis discus hannai BAM74656.1     24
 α-amylase (Amy2A) (pancreatic) 3.2.1.1 Homo sapiens AAA51724.1
AAA51723.1
AAA51725.1
AAA52280.1
AAH07060.1
AAI46998.1
BAD97183.1
CAA30099.1
CAA30100.1
CAN87444.1
NP_000690.1
P04746
P04746
1B2Y[A]
1BSI[A]
1CPU[A]
1HNY[A]
1KB3[A]
1KBB[A]
1KBK[A]
1KGU[A]
1KGW[A]
1KGX[A]
1U2Y[A]
1U30[A]
1U33[A]
1XCW[A]
1XCX[A]
1XD0[A]
1XD1[A]
1XGZ[A]
1XH0[A]
1XH1[A]
1XH2[A]
2CPU[A]
2QMK[A]
2QV4[A]
3BAI[A]
3BAJ[A]
3BAK[A]
3BAW[A]
3BAX[A]
3BAY[A]
3CPU[A]
3IJ7[A]
3IJ8[A]
3IJ9[A]
3OLD[A]
3OLE[A]
3OLG[A]
3OLI[A]
4GQQ[A]
4GQR[A]
4W93[A]
4X9Y[A]
5E0F[A]
5EMY[A]
5KEZ[A]
5TD4[A]
24
 α-amylase (salivary) (Amy1A;Amy1;HSA) 3.2.1.1 Homo sapiens AAH63129.1
AAA16183.1
AAA52279.1
AAA57345.1
AAA58368.1
AAH69347.1
AAH69463.1
AAH70302.1
AAH92444.1
AAI32986.1
AAI32988.1
AAI32996.1
AAI32998.1
AAI44453.1
BAF85030.1
CAI14928.1
CAI14929.1
CAI14930.1
CAI14932.1
NP_004029.2
P04745 1C8Q[A]
1JXJ[A]
1JXK[A]
1MFU[A]
1MFV[A]
1NM9[A]
1Q4N[X]
1SMD[A]
1XV8[A,B]
1Z32[X]
3BLK[A]
3BLP[X]
3DHP[A]
24
 α-amylase C (Amy2B) 3.2.1.1 Homo sapiens AAA35525.1
AAH11179.1
AAH20861.1
BAA14130.1
BAG53093.1
BAG54429.1
NP_066188.1
B3KXB7
D3DT76
P19961
P19961
  24
 α-amylase 1 3.2.1.1 Litopenaeus vannamei CAA54524.1
AAR19061.1
Q26193   24
 α-amylase (Amy) 3.2.1.1 Litopenaeus vannamei CAB65553.1
AAR19062.1
CAD43060.1
Q9U0F6   24
 α-amylase (Amy) 3.2.1.1 Litopenaeus vannamei CAB65552.2 Q9U0F9   24
 α-amylase 3.2.1.1 Mus musculus AAA37221.1
AAA37219.1
AAA37220.1
AAH04698.1
AAH09121.1
BAC26543.1
CAA24097.1
CAA24099.1
CAA24100.1
NP_031472.1
P00687
Q921Y7
Q99KE6
  24
 α-amylase 3.2.1.1 Mus musculus AAA37230.1
AAA37222.1
AAA37223.1
AAA37224.1
AAA37225.1
AAA37226.1
AAA37227.1
AAA37228.1
AAA37229.1
AAA37232.1
AAA37233.1
AAH94924.1
AAI00580.1
BAC37484.1
BAE21706.1
CAA24098.1
CAA26202.1
CAA26413.1
CAA26414.1
CAA26415.1
CAA26417.1
CAA26418.1
NP_033799.1
P00688
Q61297
Q61298
Q61299
Q8C5B4
  24
 α-amylase (partial) 3.2.1.1 Oryzias latipes     3VM5[A] 24
 α-amylase 3.2.1.1 Pecten maximus CAA68065.1 P91778   24
 α-amylase (Amy2A) 3.2.1.1 Pseudopleuronectes americanus AAF65827.1 Q9I9H6   24
 α-amylase (Amy1) 3.2.1.1 Rattus norvegicus AAA40725.1
AAA40731.1
NP_113690.1
P00689   24
 α-amylase (Amy1) 3.2.1.1 Rattus norvegicus AAH88228.1
BAB39466.1
Q5I0L0
Q99N59
  24
 α-amylase (PA) (pancreatic) 3.2.1.1 Struthio camelus   P83053   24
 α-amylase (Ppa;PPA) (pancreatic) 3.2.1.1 Sus scrofa AAF02828.1 P00690 1BVN[P]
1DHK[A]
1HX0[A]
1JFH[A]
1KXQ[A]
1KXT[A]
1KXV[A]
1OSE[A]
1PIF[A]
1PIG[A]
1PPI[A]
1UA3[A]
1VAH[A]
1WO2[A]
3L2L[A]
3L2M[A]
4X0N[A]
24
 amylase-1 3.2.1.1 Tetraodon nigroviridis CAC87125.1 Q8UWE5   24
 amylase-3 3.2.1.1 Tetraodon nigroviridis CAC87127.1 Q8UWE3   24
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