| Activities in Family | β-N-acetyl-4-sulfo-galactosaminidase (EC 3.2.1.-); Endo-β-1,3-N-acetylgalactosaminidase (EC 3.2.1.-); Endo-β-1,4-N-acetylgalactosaminidase (EC 3.2.1.-); Exo-β-1,3-N-acetylgalactosaminidase (EC 3.2.1.-); Exo-β-1,4-N-acetylgalactosaminidase (EC 3.2.1.-); Glycosphingolipid β-N-acetylgalactosaminidase (EC 3.2.1.-); β-N-acetylgalactosaminidase (EC 3.2.1.53); |
|---|---|
| Mechanism | Retaining e |
| 3D Structure Status | ( β / α ) 8 barrel |
| Catalytic Nucleophile/Base | carbonyl oxygen of C-2 acetamido group of substrate |
| Catalytic Proton Donor | Glu |
| Note | Created after Sumida T, Fujimoto K, Ito M. (2011) J Biol Chem. 286:14065-14072 [PMID: 21297160] |
| External resources | CAZypedia; |
| Statistics | GenBank accession (1689); Uniprot accession (6); PDB accession (19); 3D entries (8); cryst (0) |
| Archaea | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | Subf |
| β-N-acetylgalactosaminidase (NgaBa; AYL29_011390) | 3.2.1.- 3.2.1.- |
pubmed pubmed pubmed pubmed |
Candidatus Bathyarchaeota archaeon B24 | KYH36768.1 | A0A151B9Y7 | 3 | |
| Bacteria | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | Subf |
| exo-β-N-acetylgalactosaminidase (NgaBf;MT990_12505) | 3.2.1.- 3.2.1.- |
pubmed pubmed pubmed pubmed |
Bifidobacterium longum subsp. infantis JRPT | UOG10788.1 | 2 | ||
| exo-β-N-acetylgalactosaminidase (NgaBf; Bfae_31540) | 3.2.1.- 3.2.1.- |
pubmed doi pubmed doi |
Brachybacterium faecium DSM 4810 | ACU86914.1 WP_015777117.1 |
C7MB27 | 2 | |
| glycolipid exo-β-N-acetylgalactosaminidase (CpNga123;CPF_1473) | 3.2.1.53 3.2.1.- |
pubmed pubmed |
Clostridium perfringens ATCC 13124 | ABG82546.1 | A0A0H2YNR7 | 5FQE[A,B] 5FQF[A,B] 5FQG[A] 5FQH[A] 5FR0[A] |
1 |
| β-N-acetylgalactosaminidase (NgaCa;KCTCHS21_21730) | 3.2.1.53 | pubmed |
Cohnella abietis HS21 | BBI32774.1 | A0A3T1D3V8 | 8K2F[A] 8K2G[A,B] |
4 |
| exo-β-N-acetylgalactosaminidase (NgaLy) | 3.2.1.- 3.2.1.- |
pubmed pubmed pubmed pubmed |
Lacticaseibacillus yichunensis | WP_125696777.1 | 8K2N[A,B,C,D] | 2 | |
| β-N-acetylgalactosaminidase (NaNga) (DUF4091 domain-containing protein) | 3.2.1.53 | pubmed |
Niabella aurantiaca DSM 17617 | WP_018628640.1 | 8P4L[A,B,C,D,E,F,G,H,I,J,K,L] 8Q8H[A,B,C,D] |
2 | |
| glycosphingolipid β-N-acetylgalactosaminidase (NgaP; β-NGA) | 3.2.1.53 3.2.1.- |
pubmed pubmed |
Paenibacillus sp. TS12 | BAJ83606.1 | E9RH20 | 1 | |
| exo-β-N-acetylgalactosaminidase (NgaP2) | 3.2.1.- 3.2.1.- |
pubmed pubmed pubmed pubmed |
Paenibacillus sp. TS12 | BEL01682.1 | 8K2L[A] 8K2M[A] |
2 | |
| N-acetyl-β-galactosaminidase / β-N-acetylgalactosaminidase (BvGH123;BVU_2198) | 3.2.1.53 | pubmed |
Phocaeicola vulgatus ATCC 8482 | ABR39859.1 | A6L2E5 | 5L7R[A,B] 5L7U[A,B] 5L7V[A,B] |
1 |
| Eukaryota | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | Subf |
| exo-β-1,3-N-acetylgalactosaminidase (NgaAt) | 3.2.1.- | pubmed |
Arabidopsis thaliana | AEE32084.1 Q7Y231 |
8K2H[A,B] 8K2I[A,B] |
5 | |
| unclassified | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | Subf |
| β-N-acetylgalactosaminidase (NgaDssm) | 3.2.1.53 3.2.1.- |
pubmed pubmed |
unidentified | 8K2J[A] 8K2K[A] |
3 | ||
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