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Carbohydrate-Binding Module Family 70

Activities in FamilyThe hyaluronan-specific binding function of the N-terminal CBM70 module of Streptococcus pneumoniae hyaluronate lyase has been demonstrated.
3D Structure Statusβ-sandwich
NoteCreated after Suits et al. (2014) J Biol Chem 289:27264-27277 [PMID: 25100731]
Statistics GenBank accession (565); Uniprot accession (7); PDB accession (1); 3D entries (1); cryst (0)
Summary
Download CBM70 (564) Taxonomic display Structure (1)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SPNINV200_02820   Streptococcus pneumoniae INV200 CBW33916.1    
 SAMEA104035599_00332   Streptococcus pneumoniae isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8 VGM78639.1    
 SPJ_0310   Streptococcus pneumoniae JJA ACO18875.1    
 KK0381_20060 (fragment)   Streptococcus pneumoniae KK0381 BAX32126.1    
 KK0381_20050 (HyL) (fragment)   Streptococcus pneumoniae KK0381 BAX32125.1    
 KK0981_23420 (fragment)   Streptococcus pneumoniae KK0981 BAW83838.1    
 KK0981_23410 (HyL) (fragment)   Streptococcus pneumoniae KK0981 BAW83837.1    
 KK1157_21240 (fragment)   Streptococcus pneumoniae KK1157 BAX34421.1    
 MDRSPN_00289 (HysA)   Streptococcus pneumoniae MDRSPN001 BBA58495.1    
 NCTC11902_00321   Streptococcus pneumoniae NCTC11902 SQG97959.1    
 NCTC12977_02029   Streptococcus pneumoniae NCTC12977 VEE31504.1    
 NCTC13276_00295   Streptococcus pneumoniae NCTC13276 SQG33576.1    
 ERS445053_00184   Streptococcus pneumoniae NCTC7465 COT00131.1    
 NCTC7466_00296   Streptococcus pneumoniae NCTC7466 SQG01354.1    
 SpnNT_00308 (fragment)   Streptococcus pneumoniae NT_110_58 AJD71249.1    
 SPNU_0306   Streptococcus pneumoniae NU83127 BBG34197.1    
 SPP_0350   Streptococcus pneumoniae P1031 ACO21275.1    
 HA248_01595   Streptococcus pneumoniae PZ900701590 QIP99183.1    
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP004 AGI41259.1    
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP008 AGI41260.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP010 AGI41261.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP014 AGI41262.1    
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP015 AGI41263.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP017 AGI41264.1    
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP028 AGI41265.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP031 AGI41266.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP034 AGI41267.1    
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP035 AGI41268.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP036 AGI41269.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP037 AGI41270.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP038 AGI41271.1    
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP039 AGI41272.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP041 AGI41273.1    
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP043 AGI41274.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP044 AGI41275.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP066 AGI41276.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP074 AGI41278.1    
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP089 AGI41279.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP090 AGI41280.1    
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP091 AGI41281.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP092 AGI41282.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP094 AGI41283.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP096 AGI41284.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP098 AGI41285.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP100 AGI41286.1    
 hyaluronate lyase, partial (HyL)   Streptococcus pneumoniae SP102 AGI41287.1    
 hyaluronate lyase (HyL)   Streptococcus pneumoniae SP103 AGI41288.1    
 BMJ42_00426   Streptococcus pneumoniae SP49 APJ29761.1    
 BOC71_00314 (fragment)   Streptococcus pneumoniae SP61 APJ31834.1    
 BOC71_00313 (fragment)   Streptococcus pneumoniae SP61 APJ31833.1    
 BOC72_00314 (fragment)   Streptococcus pneumoniae SP64 APJ33859.1    
 BOC72_00313 (fragment)   Streptococcus pneumoniae SP64 APJ33858.1    
 C1H54_01650   Streptococcus pneumoniae SPN XDR SMC1710-32 AXJ87751.1    
 SPNA45_01722   Streptococcus pneumoniae SPNA45 CCM09007.1    
 MYY_0397   Streptococcus pneumoniae ST556 AFC94059.1    
 SPT_0364   Streptococcus pneumoniae Taiwan19F-14 ACO22630.1    
 HMPREF0837_10617 (fragment)   Streptococcus pneumoniae TCH8431/19A ADI68845.1    
 hyaluronate lyase (Hyl;SpHyl;SP0314)   Streptococcus pneumoniae TIGR4 AAK74491.1
NP_344851.1		 Q54873 4D0Q[A]
 CXP32_01570   Streptococcus pneumoniae Xen35 AUF84202.1    
 GUT183_06600 (HysA)   Streptococcus ruminantium GUT-183 BDD38422.1    
 GUT184_13790 (HysA)   Streptococcus ruminantium GUT-184 BDD41115.1    
 GUT189_06120 (HysA)   Streptococcus ruminantium GUT-189 BDD42279.1    
 SR187_3375   Streptococcus ruminantium GUT187T BBA92284.1    
 BZG42_03485   Streptococcus sp. DAT741 QHF54467.1    
 EGX96_00365   Streptococcus sp. FDAARGOS_520 AYZ03772.1    
 EGX72_05860   Streptococcus sp. FDAARGOS_521 AYY68524.1    
 EGX70_01505   Streptococcus sp. FDAARGOS_522 AYY63625.1    
 A6J68_07690   Streptococcus sp. group B FDAARGOS_229 ARC25048.1    
 NCTC10228_00503 (HylB)   Streptococcus sp. NCTC 10228 VUC96290.1    
 NCTC11567_01447 (HylB)   Streptococcus sp. NCTC 11567 VUC99377.1    
 H8787_02285   Streptococcus sp. NSJ-72 QNL42711.1    
 J5M87_09090   Streptococcus sp. zg-86 QTH47675.1    
 hyaluronidase (HylA)   Streptococcus suis CAG27053.1    
 hyaluronidase (HylA)   Streptococcus suis CAG27052.1    
 HylA (fragment)   Streptococcus suis CAC87664.1
ADF49630.1		    
 hyaluronidase (HylA) (fragment)   Streptococcus suis CAG27068.1    
 HAS68_04750   Streptococcus suis 05HAS68 AHF59038.1    
 SSU05_1215 + SSU05_1214 (fragment)   Streptococcus suis 05ZYH33 ABP90180.1
ABP90181.1		    
 hyaluronate lyase (HylA)   Streptococcus suis 1043248 AKC34794.1    
 hyaluronate lyase (HylA)   Streptococcus suis 1097205 AKC34795.1    
 ID09_06430   Streptococcus suis 6407 AIG43680.1    
 AN924_01090   Streptococcus suis 90-1330 AMU78672.1    
 hyaluronidase (HylA) (fragment)   Streptococcus suis 98015 ABD74496.1    
 SSU98_1230 + SSU98_1229 (fragment)   Streptococcus suis 98HAH33 ABP92387.1
ABP92388.1		    
 SSUA7_1066 (fragment)   Streptococcus suis A7 AER44388.1    
 CR541_06045 (fragment)   Streptococcus suis CS100322 AUW24079.1    
 hyaluronidase (HylA) (fragment)   Streptococcus suis CVCC606 ABP35951.1    
 hyaluronidase (HylA) (fragment)   Streptococcus suis CVCC607 ABP35952.1    
 SSUD9_1371   Streptococcus suis D9 AER17555.1    
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis DAT229 AKC34791.1    
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis DAT261 AKC34790.1    
 A6M16_03715   Streptococcus suis DN13 ANC99638.1    
 JZ789_04940   Streptococcus suis GX69 UCS85665.1    
 BFP66_03605   Streptococcus suis GZ0565 AOM74360.1    
 SSGZ1_1071 (fragment)   Streptococcus suis GZ1 ADE31528.1    
 CR542_06845   Streptococcus suis HA0609 AUW26221.1    
 hyaluronidase   Streptococcus suis HA1001111 ADO66679.1    
 hyaluronidase   Streptococcus suis HA1001112 ADO66680.1    
 hyaluronidase (HylA) (fragment)   Streptococcus suis HA9801 ADC54170.1    
 FPT06_00400   Streptococcus suis INT-01 QDS22866.1    
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