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Carbohydrate-Binding Module Family 40

Activities in FamilyModules of approx. 200 residues, found at the N-terminus of GH33 sialidases. Can also be found inserted in the β-propeller of GH33 sialidases. The sialic acid binding function has been demonstrated for the N-terminal CBM40 of Vibrio cholerae sialidase (Moustafa et al. (2004) J Biol Chem 279:40819-26) (PMID: 15226294).
3D Structure Statuslectin-like
External resourcesHOMSTRAD;
Statistics GenBank accession (954); Uniprot accession (25); PDB accession (69); 3D entries (8); cryst (0)
Summary
Download CBM40 (935) Taxonomic display Structure (8)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 PL85_10365   Vibrio anguillarum DSM 21597 AQM03037.1    
 PO29_12530   Vibrio anguillarum HI610 AQM17087.1    
 DYL72_11630   Vibrio anguillarum J360 AZS25596.1    
 CMV05_04215   Vibrio anguillarum VIB12 ATC56928.1    
 CK207_04320   Vibrio anguillarum VIB43 ASW80374.1    
 VAB027_2456 (NanH)   Vibrio cholerae 10432-62 AKB08334.1    
 neuraminidase (NanH)   Vibrio cholerae 13 AIL52586.1    
 NanH   Vibrio cholerae 17674 QBJ27574.1    
 NanH   Vibrio cholerae 18470 QBJ27573.1    
 EZZ25_09390   Vibrio cholerae 20000 QBJ29517.1    
 EN18_12065   Vibrio cholerae 2012EL-2176 AIT29775.1    
 BBB50_05755   Vibrio cholerae 2740-80 ANR87208.1    
 sialidase / neuraminidase (NanH;VcNA;VCSA)   Vibrio cholerae 569B 395 AAA27546.1
AAA27547.1		 A5F7A4
P0C6E9
P37060		 1KIT[A]
1W0O[A]
1W0P[A]
2W68[A,B,C]
6EKS[A]
6EKU[A]
 NanH, partial (fragment)   Vibrio cholerae 717-25 QWL55128.1    
 A1552VC_01566 (NanH)   Vibrio cholerae A1552 AWB74302.1    
 J9265_07660   Vibrio cholerae A1552 QTV01065.1    
 NanH   Vibrio cholerae AMAZONIA 3509 AAW31751.2    
 neuraminidase   Vibrio cholerae C5 APF49319.1    
 GTF72_05390   Vibrio cholerae C6706 QJS92106.1    
 IT766_07430   Vibrio cholerae C6706 QPC52482.1    
 ASZ81_01775   Vibrio cholerae CRC1106 APF56916.1    
 neuraminidase   Vibrio cholerae CRC711 APF53177.1    
 OFY13_05330   Vibrio cholerae E1 UZC91024.1    
 ASZ88_01723 (NanH)   Vibrio cholerae E1320 APF68105.1    
 EEL44_12020   Vibrio cholerae E4 AYV09698.1    
 neuraminidase   Vibrio cholerae E506 APF60361.1    
 CSW01_08950   Vibrio cholerae E7946 ATQ46817.1    
 neuraminidase   Vibrio cholerae E9120 APF71815.1    
 A6J62_08325   Vibrio cholerae FDAARGOS_223 ARB80595.1    
 FORC73_1040   Vibrio cholerae FORC_073 AYC05024.1    
 neuraminidase   Vibrio cholerae IEC224 AFC58601.1    
 GQX72_05420   Vibrio cholerae isolate CTMA_1441 QHA21694.1    
 VCLMA_A1545   Vibrio cholerae LMA3984-4 AEA78761.1    
 neuraminidase   Vibrio cholerae M2140 APF75003.1    
 neuraminidase (NanH)   Vibrio cholerae M66-2 ACP06029.1    
 VCD_002587   Vibrio cholerae MJ-1236 ACQ60753.1    
 MS6_1556   Vibrio cholerae MS6 BAP03211.1    
 N16961_VC01090 (NanH)   Vibrio cholerae N16961 AWA78170.1    
 neuraminidase   Vibrio cholerae NCTC5395 APF79274.1    
 neuraminidase (fragment)   Vibrio cholerae NCTC9420 APF83226.1    
 GTF73_05415   Vibrio cholerae O1 biovar El Tor C6709 QJS88499.1    
 GTF75_05380   Vibrio cholerae O1 biovar El Tor DRC-193A QJS81290.1    
 GTF74_05610   Vibrio cholerae O1 biovar El Tor E7946 QJS77701.1    
 C4E16_06200   Vibrio cholerae O1 biovar El Tor HC1037 AVH51954.1    
 MOV13_08200   Vibrio cholerae O1 biovar El Tor Inaba UNN87994.1    
 MOV13_16580   Vibrio cholerae O1 biovar El Tor Inaba UNN89067.1    
 GTF71_05355   Vibrio cholerae O1 biovar El Tor P27459 QJS84907.1    
 neuraminidase (NanH)   Vibrio cholerae O1 biovar El Tor R-5879 AND74814.1    
 VC1784   Vibrio cholerae O1 biovar El Tor str. N16961 AAF94933.1
NP_231419.1		    
 neuraminidase (NanH)   Vibrio cholerae O1 str. 2010EL-1786 AET26878.1    
 N900_05420   Vibrio cholerae O1 str. KW3 ALJ63797.1    
 GTH07_05400   Vibrio cholerae O37 ATCC 25872 QUX99231.1    
 GG844_12315   Vibrio cholerae O395 QGF31940.1    
 VC0395_A1381   Vibrio cholerae O395 ABQ19703.1
ACP09894.1		    
 LZM82_05370   Vibrio cholerae PanChol UIO89413.1    
 KTC41_05215   Vibrio cholerae PS4 QYO71017.1    
 NanH   Vibrio cholerae R-13169 AVK79099.1    
 NanH   Vibrio cholerae R-17917 AVK79100.1    
 NanH   Vibrio cholerae R-17918 QBJ27575.1    
 NanH   Vibrio cholerae R-18252 AVK79101.1    
 NanH   Vibrio cholerae R-18367 AVK79102.1    
 NanH   Vibrio cholerae R-18368 AVK79103.1    
 NanH   Vibrio cholerae R-18369 AVK79104.1    
 NanH   Vibrio cholerae R-18588 AVK79105.1    
 NanH   Vibrio cholerae R-18904 AVK79106.1    
 NanH   Vibrio cholerae R-18963 AVK79107.1    
 NanH   Vibrio cholerae R-18973 AVK79108.1    
 NanH   Vibrio cholerae R-19051 AVK79109.1    
 NanH   Vibrio cholerae R-19063 QBJ27571.1    
 NanH   Vibrio cholerae R-19093 QBJ27564.1    
 NanH   Vibrio cholerae R-19261 QBJ27565.1    
 NanH   Vibrio cholerae R-301 AVK79098.1    
 NanH   Vibrio cholerae R-81 AVK79097.1    
 NanH   Vibrio cholerae R-950 QBJ27566.1    
 NanH   Vibrio cholerae R-9699 QBJ27567.1    
 NanH   Vibrio cholerae R-9705 QBJ27570.1    
 NanH   Vibrio cholerae R-9760 QBJ27572.1    
 NanH   Vibrio cholerae R-9767 QBJ27568.1    
 NanH   Vibrio cholerae R-9771 QBJ27563.1    
 NanH   Vibrio cholerae R-9786 QBJ27569.1    
 F0316_05195   Vibrio cholerae RFB16 QEO41041.1    
 VCSRO5_1064 (NanH)   Vibrio cholerae RIMD 2214243 BCK17160.1    
 VCSRO17_1657 (NanH) (fragment)   Vibrio cholerae RIMD 2214255 BCK07083.1    
 VCSRO51_1146 (NanH)   Vibrio cholerae RIMD 2214289 BCK20796.1    
 VCSRO77_1311 (NanH) (fragment)   Vibrio cholerae RIMD 2214315 BCK27947.1    
 HPY04_05325   Vibrio cholerae SA3G QKU57061.1    
 Sa5Y_VC01069 (NanH)   Vibrio cholerae Sa5Y AWB70277.1    
 NanH, partial (fragment)   Vibrio cholerae Seq702-48 UBF40493.1    
 NanH, partial (fragment)   Vibrio cholerae Seq703-25 UBF40494.1    
 NanH, partial (fragment)   Vibrio cholerae Seq703-39 UBF40495.1    
 NanH, partial (fragment)   Vibrio cholerae Seq703-44 UBF40496.1    
 NanH, partial (fragment)   Vibrio cholerae Seq703-65 UBF40497.1    
 NanH, partial (fragment)   Vibrio cholerae Seq703-66 UBF40498.1    
 NanH, partial (fragment)   Vibrio cholerae Seq703-71 UBF40499.1    
 NanH, partial (fragment)   Vibrio cholerae Seq705-02 UBF40500.1    
 NanH, partial (fragment)   Vibrio cholerae Seq705-59 UBF40502.1    
 NanH, partial (fragment)   Vibrio cholerae Seq705-80 UBF40503.1    
 NanH, partial (fragment)   Vibrio cholerae Seq717-25 UBF40507.1    
 NanH, partial (fragment)   Vibrio cholerae Seq717-39 UBF40508.1    
 NanH, partial (fragment)   Vibrio cholerae Seq719-04 UBF40516.1    
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