Carbohydrate-Binding Module Family 40

Activities in FamilyModules of approx. 200 residues, found at the N-terminus of GH33 sialidases. Can also be found inserted in the β-propeller of GH33 sialidases. The sialic acid binding function has been demonstrated for the N-terminal CBM40 of Vibrio cholerae sialidase (Moustafa et al. (2004) J Biol Chem 279:40819-26) (PMID: 15226294).
3D Structure Statuslectin-like
External resourcesHOMSTRAD;
Statistics GenBank accession (600); Uniprot accession (83); PDB accession (69); 3D entries (8); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SAMEA2204095_01544 (Nanb_2)   Streptococcus pneumoniae 2245STDY5609237 VFH51494.1    
 SAMEA2204095_01209 (Nanb_1)   Streptococcus pneumoniae 2245STDY5609237 VFH50122.1    
 SAMEA2336038_01698 (NanB)   Streptococcus pneumoniae 2245STDY5699131 VFH64425.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY5699131 VFH64470.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY5699394 VFH65091.1    
 SAMEA2341150_01623 (Nanb_2) (fragment)   Streptococcus pneumoniae 2245STDY5699394 VFH65048.1    
 SAMEA2341240_01395 (NanB)   Streptococcus pneumoniae 2245STDY5699475 VGM70974.1    
 SAMEA2341240_01585 (Nana_3)   Streptococcus pneumoniae 2245STDY5699475 VGM71158.1    
 SAMEA2434444_01523 (NanB)   Streptococcus pneumoniae 2245STDY5775485 VFH68031.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY5775485 VFH68071.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY5775520 VFH69834.1    
 SAMEA2434479_01588 (NanB)   Streptococcus pneumoniae 2245STDY5775520 VFH69822.1    
 SAMEA2434504_01572 (NanB)   Streptococcus pneumoniae 2245STDY5775545 VFH73956.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY5775545 VFH73968.1    
 SAMEA2434511_01676 (NanB)   Streptococcus pneumoniae 2245STDY5775553 VGM73338.1    
 SAMEA2434511_01682 (Nana_2)   Streptococcus pneumoniae 2245STDY5775553 VGM73344.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY5775603 VFH90671.1    
 SAMEA2434561_01578 (Nanb_2)   Streptococcus pneumoniae 2245STDY5775603 VFH90628.1    
 SAMEA2434561_01271 (Nanb_1)   Streptococcus pneumoniae 2245STDY5775603 VFH88516.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY5775610 VFH91439.1    
 SAMEA2434568_01595 (NanB)   Streptococcus pneumoniae 2245STDY5775610 VFH91404.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY5775666 VFH89497.1    
 SAMEA2434623_01540 (NanB)   Streptococcus pneumoniae 2245STDY5775666 VFH89459.1    
 SAMEA2434829_01541 (Nanb_2)   Streptococcus pneumoniae 2245STDY5775874 VFH79547.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY5775874 VFH79602.1    
 SAMEA2434829_01217 (Nanb_1)   Streptococcus pneumoniae 2245STDY5775874 VFH77471.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY5868782 VFH87717.1    
 SAMEA2627289_01592 (Nanb_2)   Streptococcus pneumoniae 2245STDY5868782 VFH87674.1    
 SAMEA2627289_01227 (Nanb_1)   Streptococcus pneumoniae 2245STDY5868782 VFH85106.1    
 SAMEA2796698_01467 (NanB)   Streptococcus pneumoniae 2245STDY5982722 VFH80907.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY5982722 VFH80961.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY5983173 VFH88568.1    
 SAMEA2797120_01586 (NanB)   Streptococcus pneumoniae 2245STDY5983173 VFH88527.1    
 SAMEA3175698_01589 (NanB)   Streptococcus pneumoniae 2245STDY6020210 VFI05302.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6020210 VFI05353.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6020221 VFI10083.1    
 SAMEA3175709_01562 (NanB)   Streptococcus pneumoniae 2245STDY6020221 VFI10055.1    
 SAMEA3175728_01542 (NanB)   Streptococcus pneumoniae 2245STDY6020240 VGM75529.1    
 SAMEA3175728_01548 (Nana_2)   Streptococcus pneumoniae 2245STDY6020240 VGM75541.1    
 SAMEA3233211_01639 (NanB)   Streptococcus pneumoniae 2245STDY6030848 VFH95434.1    
 neuraminidase (Nana_4)   Streptococcus pneumoniae 2245STDY6030848 VFH95451.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6031034 VFI10264.1    
 SAMEA3233395_01583 (Nanb_2)   Streptococcus pneumoniae 2245STDY6031034 VFI10236.1    
 SAMEA3233395_01277 (Nanb_1)   Streptococcus pneumoniae 2245STDY6031034 VFI08328.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6031048 VFI04459.1    
 SAMEA3233409_01589 (NanB)   Streptococcus pneumoniae 2245STDY6031048 VFI04413.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6092581 VFI07373.1    
 SAMEA3354333_01626 (NanB)   Streptococcus pneumoniae 2245STDY6092581 VFI07325.1    
 SAMEA3354357_01664 (NanB)   Streptococcus pneumoniae 2245STDY6092613 VFI09961.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6092613 VFI09988.1    
 SAMEA3381325_01569 (NanB)   Streptococcus pneumoniae 2245STDY6092834 VFI09582.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6092834 VFI09620.1    
 SAMEA3381439_01658 (Nanb_2)   Streptococcus pneumoniae 2245STDY6092949 VFI28817.1    
 SAMEA3381439_01266 (Nanb_1)   Streptococcus pneumoniae 2245STDY6092949 VFI26901.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6092949 VFI28847.1    
 SAMEA3381491_01596 (Nanb_2)   Streptococcus pneumoniae 2245STDY6093044 VFI13832.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6093044 VFI13838.1    
 SAMEA3381491_01293 (Nanb_1)   Streptococcus pneumoniae 2245STDY6093044 VFI13537.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6105839 VFI45434.1    
 SAMEA3389228_01536 (NanB)   Streptococcus pneumoniae 2245STDY6105839 VFI45400.1    
 SAMEA3389261_01464 (Nana_2)   Streptococcus pneumoniae 2245STDY6105855 VGM83091.1    
 SAMEA3389261_01458 (NanB)   Streptococcus pneumoniae 2245STDY6105855 VGM83073.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6106337 VFI19835.1    
 SAMEA3390054_01590 (NanB)   Streptococcus pneumoniae 2245STDY6106337 VFI19788.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6106372 VFI27705.1    
 SAMEA3389940_01191 (Nanb_1)   Streptococcus pneumoniae 2245STDY6106372 VFI25948.1    
 SAMEA3389940_01504 (Nanb_2)   Streptococcus pneumoniae 2245STDY6106372 VFI27678.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6106384 VFI28196.1    
 SAMEA3389963_01562 (NanB)   Streptococcus pneumoniae 2245STDY6106384 VFI28166.1    
 SAMEA3431348_01661 (Nana_3)   Streptococcus pneumoniae 2245STDY6106635 VGM77445.1    
 SAMEA3431348_01275 (Nanb_1)   Streptococcus pneumoniae 2245STDY6106635 VGM77066.1    
 SAMEA3431348_01655 (Nanb_2)   Streptococcus pneumoniae 2245STDY6106635 VGM77439.1    
 SAMEA3431351_01556 (NanB)   Streptococcus pneumoniae 2245STDY6106637 VFI28040.1    
 neuraminidase (Nana_2)   Streptococcus pneumoniae 2245STDY6106637 VFI28070.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6106751 VFI23650.1    
 SAMEA3431383_01533 (NanB)   Streptococcus pneumoniae 2245STDY6106751 VFI23614.1    
 SAMEA3713867_01281 (Nanb_1)   Streptococcus pneumoniae 2245STDY6178787 VFI38112.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6178787 VFI40904.1    
 SAMEA3713867_01662 (Nanb_2)   Streptococcus pneumoniae 2245STDY6178787 VFI40858.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6178826 VFI44829.1    
 SAMEA3713960_01711 (NanB)   Streptococcus pneumoniae 2245STDY6178826 VFI44784.1    
 SAMEA3713964_01314 (Nanb_1)   Streptococcus pneumoniae 2245STDY6178828 VFI53507.1    
 SAMEA3713964_01618 (Nanb_2)   Streptococcus pneumoniae 2245STDY6178828 VFI54416.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6178828 VFI54437.1    
 SAMEA3714019_01609 (NanB)   Streptococcus pneumoniae 2245STDY6178854 VGM82218.1    
 SAMEA3714019_01615 (Nana_2)   Streptococcus pneumoniae 2245STDY6178854 VGM82236.1    
 SAMEA3714262_01324 (Nanb_1)   Streptococcus pneumoniae 2245STDY6179186 VFI48247.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6179186 VFI48857.1    
 SAMEA3714262_01530 (Nanb_2)   Streptococcus pneumoniae 2245STDY6179186 VFI48840.1    
 C4N11_06265   Streptococcus pneumoniae 335 AVD75144.1    
 C4N11_08635   Streptococcus pneumoniae 335 AVD75579.1    
 C4N11_08660   Streptococcus pneumoniae 335 AVD75584.1    
 neuraminidase (NanB)   Streptococcus pneumoniae 521 QBK28617.1    
 sialidase A (NanA) 3.2.1.18 Streptococcus pneumoniae 6 CAA51473.1
ACJ76903.1
B8XTT3
P62575
Q59959
4C1W[A]
4C1X[A]
4ZXK[A,B]
 sialidase B (NanB) 3.2.1.18 Streptococcus pneumoniae 6 AAC44396.1
AAW08718.1
Q54727  
 SP670_0950   Streptococcus pneumoniae 670-6B ADM91015.1 E0TMG6  
 SP670_1783   Streptococcus pneumoniae 670-6B ADM91835.1 E0TSF6  
 SP670_1776   Streptococcus pneumoniae 670-6B ADM91828.1 E0TSE9  
 HKM25_1721 (NanB)   Streptococcus pneumoniae 6A-10 QJS37426.1    
 HKM25_1726   Streptococcus pneumoniae 6A-10 QJS37431.1    
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