Carbohydrate-Binding Module Family 40

Known ActivitiesModules of approx. 200 residues, found at the N-terminus of GH33 sialidases. Can also be found inserted in the β-propeller of GH33 sialidases. The sialic acid binding function has been demonstrated for the N-terminal CBM40 of Vibrio cholerae sialidase (Moustafa et al. (2004) J Biol Chem 279:40819-26) (PMID: 15226294).
3D Structure Statuslectin-like
External resourcesHOMSTRAD; InterPro; PFAM;
Statistics GenBank accession (128); Uniprot accession (82); PDB accession (14); 3D entries (4); cryst (0)
All (106) Bacteria (105) Eukaryota (1) Structure (4 )
Bacteria
Protein Name EC#OrganismGenBankUniprotPDB/3D
 exo-α-sialidase (NanJ;CPE0553)   Clostridium perfringens str. 13 BAB80259.1
NP_561469.1
Q8XMY5 2V73[A,B]
 (trans-)sialidase B (NanB;SP1687)   Streptococcus pneumoniae TIGR4 AAK75766.1
NP_346126.1
  2JKB[A]
2VW0[A]
2VW1[A]
2VW2[A]
 sialidase (NanH)   Vibrio cholerae 569B 395 AAA27546.1
AAA27547.1
P37060.1 1KIT[A]
1W0O[A]
1W0P[A]
2W68[A,B,C]
 sialidase (NanH)   Vibrio cholerae 569B 395 AAA27546.1 P37060.1 1KIT[A]
1W0O[A]
1W0P[A]
Eukaryota
Protein Name EC#OrganismGenBankUniprotPDB/3D
 sialidase L   Macrobdella decora AAC47263.1 Q27701 1SLI[A]
1SLL[A]
2SLI[A]
3SLI[A]
4SLI[A]




Last update: 2012-01-31 © Copyright 1998-2012
AFMB - CNRS - Universités Aix-Marseille I & II