| Known Activities | Modules of approx. 200 residues, found at the N-terminus of GH33 sialidases. Can also be found inserted in the b-propeller of GH33 sialidases. The sialic acid binding function has been demonstrated for the N-terminal CBM40 of Vibrio cholerae sialidase (Moustafa et al. (2004) J Biol Chem 279:40819-26) (PMID: 15226294). |
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| 3D Structure Status | lectin-like |
| External resources | HOMSTRAD; |
| Statistics | GenBank accession (145); Uniprot accession (84); PDB accession (31); 3D entries (5); cryst (0) |
| Bacteria | ||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | |
| exo-α-sialidase (NanJ;CPE0553) | 3.2.1.18 | Clostridium perfringens str. 13 | BAB80259.1 NP_561469.1 |
Q8XMY5 | 2V73[A,B] | |
| (trans-)sialidase B (NanB;SP1687) | 2.4.1.- 2.4.1.- 3.2.1.18 3.2.1.18 |
Streptococcus pneumoniae TIGR4 | AAK75766.1 NP_346126.1 |
2JKB[A] 2VW0[A] 2VW1[A] 2VW2[A] 4FOQ[A] 4FOV[A] 4FOW[A] 4FOY[A] 4FP2[A] 4FP3[A] 4FPC[A] 4FPE[A] 4FPF[A] 4FPG[A] 4FPH[A] 4FPJ[A] 4FPK[A] 4FPL[A] 4FPO[B] 4FPY[A] 4FQ4[A] |
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| sialidase / neuraminidase (NanH;VcNA) | 3.2.1.18 | Vibrio cholerae 569B 395 | AAA27546.1 | P37060 | 1KIT[A] 1W0O[A] 1W0P[A] |
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| sialidase / neuraminidase (NanH;VcNA) | 3.2.1.18 | Vibrio cholerae 569B 395 | AAA27546.1 AAA27547.1 |
P37060 | 1KIT[A] 1W0O[A] 1W0P[A] 2W68[A,B,C] |
|
| Eukaryota | ||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | |
| sialidase L | 3.2.1.18 3.2.1.18 |
Macrobdella decora | AAC47263.1 | Q27701 | 1SLI[A] 1SLL[A] 2SLI[A] 3SLI[A] 4SLI[A] |
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