Auxiliary Activity Family 15

Activities in Familylytic cellulose monooxygenase (C1-hydroxylating) (EC 1.14.99.54); lytic chitin monooxygenase (EC 1.14.99.53)
Mechanism monooxygenase
NoteFamily created after Sabbadin and colleagues who have shown the copper-dependent LPMO activity of two AA15 enzymes from Thermobia domestica (PMID=29472725).
Statistics GenBank accession (426); Uniprot accession (4); PDB accession (1); 3D entries (1); cryst (0)
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 lytic chitin monooxygenase (H257_05075) 1.14.99.53 doi
Aphanomyces astaci APO3 ETV82437.1 W4GRV7  
 bifunctional lytic polysaccharide monooxygenase active on cellulose and chitin (TdAA15A) 1.14.99.53
1.14.99.54
pubmed
pubmed
Thermobia domestica SIW61372.1 A0A2N8U5K6
A0A2R2JFH0
5MSZ[A]
 lytic polysaccharide monooxygenase active on chitin (TdAA15B) 1.14.99.53 pubmed
Thermobia domestica SIW61373.2 A0A2N8U5I8  
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