Activities in Family	Lytic xylan monooxygenase / xylan oxidase (C4-dehydrogenating) (EC 1.14.99.-); Lytic chitin monooxygenase (EC 1.14.99.53); Lytic cellulose monooxygenase (C1-hydroxylating) (EC 1.14.99.54); Lytic cellulose monooxygenase (C4-dehydrogenating) (EC 1.14.99.56);
Mechanism	monooxygenase
Note	AA10 (formerly CBM33). The enzymes in this family were originally classified as chitin-binding proteins (CBM33); Vaaje-Kolstad et al. have shown that these proteins are in fact oxidative enzymes [PMID - 20929773]. They are now reclassified in the AA category of CAZy. Because a significant literature is associated with the old name CBM33, we recommend to describe these enzymes as "AA10 (formerly CBM33)".
Statistics	GenBank accession (11310); Uniprot accession (44); PDB accession (50); 3D entries (27); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
lytic chitin monooxygenase B (AsLPMO10B; VSAL_II0217) (LPMO10B)	1.14.99.53	Aliivibrio salmonicida LFI1238	CAQ80971.1	B6EQJ6	7OKR[A]
lytic chitin monooxygenase (ChbB;BaAA10A;BaCBM33;Rbam17540;BAMF_1859)	1.14.99.53	Bacillus amyloliquefaciens DSM 7 = ATCC 23350	CBI42985.1	E1UUV3	2YOW[A,B] 1.80 2YOX[A,B] 1.90 2YOY[A,B] 1.70 5IJU[A,B] 1.70
LPMO10A (CPQ91_02620) (BlLpmo10A)		Bacillus licheniformis ATCC 9789	ATI74801.1		5LW4[A] NMR
lytic chitin monooxygenase (C1-specific) / chitin binding protein (ChbB;Cbp;BliCBP;BlAA10A;BLi00521;BL00145)	1.14.99.53	Bacillus licheniformis DSM 13 = ATCC 14580	AAU39477.1 AAU22121.1 ACW83017.1	D0EW67 Q62YN7 Q65N87	6TWE[A] NMR
chitin-active lytic monooxygenase (Lpmo10A; BtLPMO10A)	1.14.99.53	Bacillus thuringiensis serovar kurstaki ACCC 10066	AJP62637.1	A0A0C5K362 A0A0F6FRT6	5WSZ[A,B,C,D] 2.57
BURPS1710b_0114 (BpAA10A)		Burkholderia pseudomallei 1710b	ABA49030.1		3UAM[A,B,C,D,E,F] 2.00
lytic chitin monooxygenase (CjLPMO10A; CJA_2191) (CjLPMO10A)	1.14.99.53	Cellvibrio japonicus Ueda107	ACE83992.1	B3PJ79	5FJQ[A,B,C] 1.85
chitin oxidative-cleaving enzyme (EfAA10A;EF0362;EfCBM33A;EfaCBM33)	1.14.99.53	Enterococcus faecalis V583	AAO80225.1 NP_814154.1	Q838S1	4A02[A] 0.95 4ALC[A] 1.49 4ALE[A] 1.48 4ALQ[A] 1.48 4ALR[A] 1.49 4ALS[A] 1.47 4ALT[A] 1.49
lytic chitin monooxygenase C1-hydroxylating / chitinase (Jden_1381)(JdLPMO10A) (LPMO10A)	1.14.99.53	Jonesia denitrificans DSM 20603	ACV09037.1	C7R4I0	5AA7[A,B] 1.55 5VG0[A,B] 1.10 5VG1[A,B] 2.10
lytic polysaccharide monooxygenase (KpLPMO10A)	1.14.99.53 1.14.99.54 1.14.99.56 1.14.99.-	Kitasatospora papulosa DSM41643	WP_030125046.1	A0A285DJD7 A0A329CVF1 A0A4P7DN87 A0A8D3WFW9	6NDQ[A,B] 1.60
LMRG_01781		Listeria monocytogenes 10403S	AEO07443.1		5L2V[A,B] 1.10
Micau_1630		Micromonospora aurantiaca ATCC 27029	ADL45185.1		5OPF[A] 1.08
lytic chitin monooxygenase (CbpL;plu2352)	1.14.99.53	Photorhabdus laumondii subsp. laumondii TTO1	CAE14645.1 NP_929598.1	Q7N4I5	6T5Z[A,B,C] 1.60
chitin-binding protein (CbpD;PA0852)		Pseudomonas aeruginosa PAO1	AAG04241.1 NP_249543.1		7SQX[A] 3.00 8C5N[A] 0.75
lytic chitin monooxygenase (C1-specific) / chitin-binding protein (Cbp21;CBP21;Cbp;SmAA10A;SmLPMO10A)	1.14.99.53	Serratia marcescens BJL200	AAU88202.1	O83009	2BEM[A,B,C] 1.55 2BEN[A,B] 1.8 2LHS[A] NMR
lytic chitin monooxygenase (SCO1734;SCI11.23)	1.14.99.53	Streptomyces coelicolor A3(2)	CAB50949.1 NP_626007.1		7ZJB[A] 1.37
lytic cellulose monooxygenase (C1-hydroxylating/C4-dehydrogenating) (ScLPMO10B;SCO0643;SCF91.03c)	1.14.99.54 1.14.99.56	Streptomyces coelicolor A3(2)	CAB61160.1 NP_624952.1	Q9RJC1	4OY6[A] 1.29 4OY8[A] 1.40
lytic cellulose monooxygenase (C1-hydroxylating) (CelS2;ScLPMO10C;ScAA10C;SCO1188;SCG11A.19)	1.14.99.54	Streptomyces coelicolor A3(2)	CAB61600.1 AHA82091.1 NP_625478.1	Q9RJY2 V5N5H9	4OY7[A,B,C,D,E,F,G,H] 1.50
chitin-active lytic monooxygenase (SliLPMO10E / SLI_3182	1.14.99.53	Streptomyces lividans 1326	EOY47895.1	A0A7U9DRA2 D6EWM4	5FTZ[A] 1.38
lytic cellulose monooxygenase (TtAA10A; TERTU_0046) (AA10A)	1.14.99.54 1.14.99.56	Teredinibacter turnerae T7901	ACR14100.1	C5BKQ9	6RW7[A] 1.40
lytic cellulose monooxygenase (C1-hydroxylating/C4-dehydrogenating) (Tfu_1268;E7;TfLPMO10A)	1.14.99.54 1.14.99.56	Thermobifida fusca YX	AAZ55306.1	Q47QG3	4GBO[A,B] 2.00 5UIZ[A,B] 2.00
lytic chitin monooxygenase (VIBHAR_04739)	1.14.99.53	Vibrio campbellii ATCC BAA-1116	ABU72648.1		8GUL[A,B] 2.44 8GUM[A,B] 2.35
lytic chitin monooxygenase / N-acetylglucosamine-binding protein A (GbpA;VcGbpA;VcAA10B;VCA0811)	1.14.99.53	Vibrio cholerae O1 biovar El Tor str. N16961	AAF96709.1 ABW34704.1 NP_233197.1	A9Y370 Q9KLD5	2XWX[A,B] 1.80 7PB6[A,B] 1.50 7PB7[A,B] 1.80 8CC3[A,B] 1.13 8CC5[A,B] 1.62
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
lytic chitin monooxygenase	1.14.99.53	Tectaria macrodonta	AFR32946.1	W5QLL4	6IF7[A] 2.20
Viruses
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
fusolin (ACV034)	1.14.99.53	Anomala cuprea entomopoxvirus CV6M	BAA25629.1 BAO49394.1	O70709	4YN1[A] 1.90
fusolin (partial)		unidentified entomopoxvirus			4YN2[A] 2.02
fusolin		unidentified entomopoxvirus / Melolontha melolontha entomopoxvirus (MMEV)	CAA54706.1 ABE23214.1		4OW5[A] 1.90 4X27[A] 2.40 4X29[A] 2.41
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