Auxiliary Activity Family 10

Activities in FamilyAA10 (formerly CBM33) proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs); some proteins have been shown to act on chitin, others on cellulose; lytic cellulose monooxygenase (C1-hydroxylating) (EC; lytic cellulose monooxygenase (C4-dehydrogenating)(EC; lytic chitin monooxygenase (EC; lytic xylan monooxygenase / xylan oxidase (glycosidic bond-cleaving) (EC 1.14.99.-)
Mechanism monooxygenase
NoteAA10 (formerly CBM33). The enzymes in this family were originally classified as chitin-binding proteins (CBM33); Vaaje-Kolstad et al. have shown that these proteins are in fact oxidative enzymes [PMID - 20929773]. They are now reclassified in the AA category of CAZy. Because a significant literature is associated with the old name CBM33, we recommend to describe these enzymes as "AA10 (formerly CBM33)".
Statistics GenBank accession (5907); Uniprot accession (382); PDB accession (38); 3D entries (22); cryst (0)
All (5759) Archaea (5) Bacteria (5554) Eukaryota (9) Viruses (189) unclassified (2) Structure (22) Characterized (25)
| 1 | ... | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | ... | 56 |
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BB341_18415   Streptomyces clavuligerus F613-1 ANW20046.1    
 BB341_27960   Streptomyces clavuligerus F613-1 ANW22176.1    
 SCO6345 or SC3A7.13   Streptomyces coelicolor A3(2) CAA20076.1
 SCO1734 (SCI11.23)   Streptomyces coelicolor A3(2) CAB50949.1
 chitin-binding protein (Chb3;SCO0481;SCF80.02)   Streptomyces coelicolor A3(2) CAB57190.1
 lytic cellulose monooxygenase (C1-hydroxylating/C4-dehydrogenating) (ScLPMO10B;SCO0643;SCF91.03c)
Streptomyces coelicolor A3(2) CAB61160.1
Q9RJC1 4OY6[A]
 lytic cellulose monooxygenase (C1-hydroxylating) (CelS2;ScLPMO10C;ScAA10C;SCO1188;SCG11A.19) Streptomyces coelicolor A3(2) CAB61600.1
Q9RJY2 4OY7[A,B,C,D,E,F,G,H]
 SCO2833 (Chb)   Streptomyces coelicolor A3(2) CAB65563.1
 SCO7225 / SC2H12.24 (ChiM)   Streptomyces coelicolor A3(2) CAB94648.1
 FQ762_14515   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI42933.1    
 FQ762_32765   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI46156.1    
 FQ762_08820   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI41925.1    
 FQ762_37285   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI46974.1    
 FQ762_03180   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI40900.1    
 FQ762_02360   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI40748.1    
 FQ762_05975   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI41415.1    
 CP976_09845   Streptomyces coeruleorubidus ATCC 13740 QEV24422.1    
 CP976_33095   Streptomyces coeruleorubidus ATCC 13740 QEV28479.1    
 CP976_33655   Streptomyces coeruleorubidus ATCC 13740 QEV28577.1    
 CP976_16515   Streptomyces coeruleorubidus ATCC 13740 QEV25602.1    
 CP976_40950   Streptomyces coeruleorubidus ATCC 13740 QEV29846.1    
 B446_14915   Streptomyces collinus Tu 365 AGS69801.1    
 B446_09025   Streptomyces collinus Tu 365 AGS68629.1    
 B446_28485   Streptomyces collinus Tu 365 AGS72503.1    
 TU94_28680   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP04830.1    
 TU94_04680   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP05517.1    
 TU94_07320   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP01316.1    
 TU94_12410   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP02168.1    
 TU94_31990   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP05354.1    
 BN159_5438   Streptomyces davaonensis JCM 4913 CCK29817.1    
 BN159_2112   Streptomyces davaonensis JCM 4913 CCK26491.1    
 BN159_2283   Streptomyces davaonensis JCM 4913 CCK26662.1    
 BN159_2424   Streptomyces davaonensis JCM 4913 CCK26803.1    
 BN159_6820   Streptomyces davaonensis JCM 4913 CCK31199.1    
 C4B68_31870   Streptomyces dengpaensis XZHG99 AVH59584.1    
 C4B68_25455   Streptomyces dengpaensis XZHG99 AVH61419.1    
 C4B68_09170   Streptomyces dengpaensis XZHG99 AVH55915.1    
 EIZ62_21265   Streptomyces ficellus NRRL 8067 QGV80481.1    
 EIZ62_26485   Streptomyces ficellus NRRL 8067 QGV81395.1    
 KY5_0914   Streptomyces formicae KY5 ATL25932.1    
 KY5_7882   Streptomyces formicae KY5 ATL32900.1    
 KY5_0261   Streptomyces formicae KY5 ATL25279.1    
 KY5_1615   Streptomyces formicae KY5 ATL26633.1    
 KY5_8040c   Streptomyces formicae KY5 ATL33058.1    
 KY5_2984c   Streptomyces formicae KY5 ATL28002.1    
 CP974_00630   Streptomyces fradiae ATCC 10745 = DSM 40063 QEV10768.1    
 D3X13_21780   Streptomyces fradiae NKZ-259 AYA18508.1    
 D3X13_34760   Streptomyces fradiae NKZ-259 AYA20711.1    
 D3X13_27480   Streptomyces fradiae NKZ-259 AYA19499.1    
 D3X13_35345   Streptomyces fradiae NKZ-259 AYA20799.1    
 D3X13_35350   Streptomyces fradiae NKZ-259 AYA20800.1    
 D3X13_32885   Streptomyces fradiae NKZ-259 AYA20415.1    
 SFUL_166   Streptomyces fulvissimus DSM 40593 AGK75150.1    
 SFUL_2426   Streptomyces fulvissimus DSM 40593 AGK77377.1    
 SFUL_182   Streptomyces fulvissimus DSM 40593 AGK75166.1    
 SFUL_306   Streptomyces fulvissimus DSM 40593 AGK75290.1    
 SFUL_1272   Streptomyces fulvissimus DSM 40593 AGK76244.1    
 SFUL_2389   Streptomyces fulvissimus DSM 40593 AGK77342.1    
 CNQ36_12880   Streptomyces fungicidicus TXX3120 AYL36252.1    
 CNQ36_25965   Streptomyces fungicidicus TXX3120 AYL38545.1    
 CNQ36_18300   Streptomyces fungicidicus TXX3120 AYL39561.1    
 CNQ36_33205   Streptomyces fungicidicus TXX3120 AYL40284.1    
 CNQ36_07370   Streptomyces fungicidicus TXX3120 AYL35266.1    
 CNQ36_25410   Streptomyces fungicidicus TXX3120 AYL38447.1    
 CP966_13540   Streptomyces galilaeus ATCC 14969 QEU66189.1    
 CP966_07240   Streptomyces galilaeus ATCC 14969 QEU65081.1    
 CP966_27950   Streptomyces galilaeus ATCC 14969 QEU70418.1    
 B1H19_10660   Streptomyces gilvosporeus F607 ARF54602.1    
 B1H19_35905   Streptomyces gilvosporeus F607 ARF58855.1    
 B1H19_15870   Streptomyces gilvosporeus F607 ARF55465.1    
 SGLAU_00180   Streptomyces glaucescens GLA.O AIR96066.1    
 SGLAU_31955   Streptomyces glaucescens GLA.O AIS02325.1    
 SGLAU_26665   Streptomyces glaucescens GLA.O AIS01271.1    
 SGLAU_12880   Streptomyces glaucescens GLA.O AIR98569.1    
 SGLAU_07660   Streptomyces glaucescens GLA.O AIR97547.1    
 SGLAU_17860   Streptomyces glaucescens GLA.O AIR99535.1    
 SGLAU_31800   Streptomyces glaucescens GLA.O AIS02294.1    
 WQO_00930   Streptomyces globisporus C-1027 ALU92050.1    
 WQO_12010   Streptomyces globisporus C-1027 ALU94010.1    
 WQO_06440   Streptomyces globisporus C-1027 ALU93016.1    
 DIJ69_22235   Streptomyces globisporus TFH56 AWL88277.1    
 DIJ69_33125   Streptomyces globisporus TFH56 AWL90120.1    
 DIJ69_27915   Streptomyces globisporus TFH56 AWL89243.1    
 C0216_26370   Streptomyces globosus LZH-48 AXE26509.1    
 C0216_32210   Streptomyces globosus LZH-48 AXE28155.1    
 AVL59_41855   Streptomyces griseochromogenes ATCC 14511 ANP55276.1    
 AVL59_35430   Streptomyces griseochromogenes ATCC 14511 ANP54161.1    
 AVL59_11930   Streptomyces griseochromogenes ATCC 14511 ANP50228.1    
 DWG14_00994 (Cbpd_1)   Streptomyces griseorubiginosus 3E-1 AYC36784.1    
 DWG14_02114 (Cbpd_3)   Streptomyces griseorubiginosus 3E-1 AYC37895.1    
 DWG14_02018 (Cbpd_2)   Streptomyces griseorubiginosus 3E-1 AYC37800.1    
 DWG14_06707 (CpbD)   Streptomyces griseorubiginosus 3E-1 AYC42412.1    
 DWG14_05273 (GbpA)   Streptomyces griseorubiginosus 3E-1 AYC40995.1    
 ELQ87_09225   Streptomyces griseoviridis F1-27 AZS84450.1    
 ELQ87_08760   Streptomyces griseoviridis F1-27 AZS84369.1    
 ELQ87_24395   Streptomyces griseoviridis F1-27 AZS87042.1    
 ELQ87_38700   Streptomyces griseoviridis F1-27 AZS89523.1    
 ELQ87_30955   Streptomyces griseoviridis F1-27 AZS90143.1    
 DDJ31_00535   Streptomyces griseoviridis K61 QCN83638.1    
 DDJ31_08310   Streptomyces griseoviridis K61 QCN90449.1    

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