Mechanism	b-elimination
3D Structure Status	( α / α ) 6 toroid + anti-parallel β-sheet
External resources	CAZypedia;
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (1598); Uniprot accession (11); PDB accession (21); 3D entries (2); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)	Subf
hyaluronate lyase (HylB;SaHyl;Gbs1270)	4.2.2.1	Streptococcus agalactiae NEM316	CAD46929.1 AAA56749.1 NP_735714.1	Q53591	1F1S[A] 2.10 1I8Q[A] β-D-4-deoxy-GlcpA-(1-3)-β-D-GlcpNAc 2.20 1LXM[A] β-D-GalpA-(1-3)-β-D-GlcpNAc-(1-4)-β-D-GlcpA-(1-3)-β-D-GlcpNAc-(1-4)-β-D-GlcpA-(1-3)-β-D-GlcpNAc 2.20	1
hyaluronate lyase (HysA)	4.2.2.1	Streptococcus pneumoniae R6	AAK99090.1 AAA53685.1 AAA53686.1 AAT16666.1 ACK14456.1 ACW45175.1 NP_357880.1	Q54873 Q8CWU3	1C82[A] α-L-4-deoxy-IdopA-(1-3)-β-D-GlcpNAc 1.70 1EGU[A] 1.56 1F9G[A] 2.00 1LOH[A] β-D-GalpA-(1-3)-β-D-GlcpNAc-(1-4)-β-D-GlcpA-(1-3)-β-D-GlcpNAc-(1-4)-β-D-GlcpA-(1-3)-β-D-GlcpNAc 2.00 1LXK[A] β-D-GlcpA-(1-3)-β-D-GlcpNAc-(1-4)-β-D-GlcpA-(1-3)-β-D-GlcpNAc 1.53 1N7N[A] 1.55 1N7O[A] 1.50 1N7P[A] 1.55 1N7Q[A] β-D-GalpA-(1-3)-β-D-GlcpNAc-(1-4)-β-D-GlcpA-(1-3)-β-D-GlcpNAc-(1-4)-β-D-GlcpA-(1-3)-β-D-GlcpNAc 2.30 1N7R[A] β-D-GalpA-(1-3)-β-D-GlcpNAc-(1-4)-β-D-GlcpA-(1-3)-β-D-GlcpNAc-(1-4)-β-D-GlcpA-(1-3)-β-D-GlcpNAc 2.20 1OJM[A] α-L-4-deoxy-IdopA-(1-3)-β-D-GalpNAc 1.78 1OJN[A] 1.60 1OJO[A] 1.75 1OJP[A] 1.90 1W3Y[A] 1.65 2BRP[A] 2.0 2BRV[X] 3.3 2BRW[A,B] 2.8	1
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