Mechanism | b-elimination |
---|---|
Note | Family created after Ndeh et al., J. Biol. Chem. (2018) 293:17906-17916 [PMID=30262663] who have shown that the PL29 enzyme BT_3328 of Bacteroides thetaiotaomicron is active on chondroitin sulfate, dermatan sulfate and hyaluronic acid. |
External resources | CAZypedia; |
Statistics | GenBank accession (347); Uniprot accession (2); |
Activity Id | EC# | Activity Name | Residue -2 | Bond -1 | Residue -1 | Reacting Bond | Residue +1 | Bond +1 | Residue +2 | Reactant |
L356 | 4.2.2.1 | hyaluronate lyase | bDGlcpA | 1,3 | bDGlcpNAc | 1,4 | bDGlcpA | 1,3 | bDGlcpNAc | |
L359 | 4.2.2.5 | chondroitin AC lyase | bDGlcpA | 1,3 | bDGalpNAc_4/6S | 1,4 | bDGlcpA | 1,3 | bDGalpNAc_4/6S | |
L368 | 4.2.2.19 | chondroitin B lyase | aLIdopA | 1,3 | bDGalpNAc_4S | 1,4 | aLIdopA | 1,3 | bDGalpNAc_4S | |
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