Polysaccharide Lyase Family 29

Mechanism b-elimination
NoteFamily created after Ndeh et al., J. Biol. Chem. (2018) 293:17906-17916 [PMID=30262663] who have shown that the PL29 enzyme BT_3328 of Bacteroides thetaiotaomicron is active on chondroitin sulfate, dermatan sulfate and hyaluronic acid.
External resourcesCAZypedia;
Statistics GenBank accession (347); Uniprot accession (2);
Activity IdEC#Activity NameResidue -2Bond -1Residue -1 Reacting BondResidue +1Bond +1Residue +2Reactant
L356 4.2.2.1 hyaluronate lyase bDGlcpA 1,3 bDGlcpNAc 1,4 bDGlcpA 1,3 bDGlcpNAc
L359 4.2.2.5 chondroitin AC lyase bDGlcpA 1,3 bDGalpNAc_4/6S 1,4 bDGlcpA 1,3 bDGalpNAc_4/6S
L368 4.2.2.19 chondroitin B lyase aLIdopA 1,3 bDGalpNAc_4S 1,4 aLIdopA 1,3 bDGalpNAc_4S
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