Mechanism | b-elimination |
---|---|
3D Structure Status | 7-bladed β-propeller |
Note | Family created after Kopel et al. (2016) J. Biol. Chem., 291, 5871-5878 [PMID=26763234]. Ulvan lyases cleave the bond between 3-sulfated rhamnose (Rha3S) linked to either D-glucuronic acid (GlcA) or L-iduronic acid (IduA) in the marine polysaccharide ulvan. Members of this family are known to specifically cleave the b(1,4) glycosidic bond between GlcUA and R3S residues by b-elimination. |
External resources | CAZypedia; |
Statistics | GenBank accession (80); Uniprot accession (6); PDB accession (6); 3D entries (2); cryst (0) |
Activity Id | EC# | Activity Name | Residue -2 | Bond -1 | Residue -1 | Reacting Bond | Residue +1 | Bond +1 | Residue +2 | Reactant |
L389 | 4.2.2.- | b-D-glucuronate ulvan lyase | bDGlcpA | 1,4 | aLRhap_3S | 1,4 | bDGlcpA | 1,4 | aLRhap_3S | |
L390 | 4.2.2.- | a-L-iduronate ulvan lyase | aLIdopA | 1,4 | aLRhap_3S | 1,4 | aLIdopA | 1,4 | aLRhap_3S | |
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