Activities in Family	N-acetylgalactosaminyltransferase (EC 2.4.1.-); UDP-GalNAc: β-1,4-N-acetylgalactosaminyltransferase (EC 2.4.1.-); UDP-GlcNAc: N-acetylglucosamine-β-1,4-N-acetylglucosaminyltransferase (EC 2.4.1.-); β-1,4-N-acetylgalactosaminyltransferase (EC 2.4.1.-); UDP-Gal: xylosylprotein β-1,4-galactosyltransferase (EC 2.4.1.133); UDP-GalNAc: β-1,3-glucuronyl-galactosylproteoglycan β-1,4-N-acetylgalactosaminyltransferase (EC 2.4.1.174); UDP-GalNAc: β-1,3-glucuronyl-N-acetylgalactosaminyl-proteoglycan β-1,4-N-acetylgalactosaminyltransferase (EC 2.4.1.175); Lactose synthase (EC 2.4.1.22); UDP-Gal: neolactotriaosylceramide β-1,4-galactosyltransferase (EC 2.4.1.275); UDP-Gal: β-N-acetylglucosaminylglycopeptide β-1,4-galactosyltransferase (EC 2.4.1.38); N-acetyllactosamine synthase (EC 2.4.1.90);
Mechanism	Inverting
3D Structure Status	GT-A
External resources	CFG(Glycosphingolipid); CFG(O-linked); CFG(Terminal); Glymap;
Commercial Enzyme Provider(s)	CHEMILY;
Statistics	GenBank accession (2137); Uniprot accession (85); PDB accession (55); 3D entries (4); cryst (0)

Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
β-1,4-galactosyltransferase T1 (B4Gal-T1;GgtB2;GalT)	2.4.1.22 2.4.1.38 2.4.1.90	Bos taurus	AAA30534.1 AAA30659.1 AAI20416.1 AAM54035.2 CAA32695.1 NP_803478.1	P08037	1FGX[A,B] 2.40 1FR8[A,B] 2.40 1J8W[B] β-D-Glcp 2.00 1J8X[B] 2.00 1J92[B] β-D-GlcpNAc 2.00 1J94[B] 2.50 1JN8[B] β-D-GlcpNAc 2.00 1JNA[B] <non_carb>-(1-2)-β-D-GlcpN 2.30 1JNC[B] 2.30 1KYB[A] α-D-Galp-(1-1)-<non_carb> 2.80 1L7W[B] 2.10 1NF5[B,D] β-D-Glcp 2.00 1NHE[B,D] 2.50 1NKH[B,D] 2.00 1NMM[B,D] β-D-GlcpNAc 2.00 1NQI[B,D] β-D-GlcpNAc 2.00 1NT7[B] 2.32 1NWG[B,D] <non_carb>-(1-2)-β-D-GlcpN 2.32 1O0R[A,B] α-D-Galp-(1-1)-<non_carb> 2.30 1O23[B,D] 2.32 1OQM[B,D] 2.10 1PZT[A] 1.92 1PZY[B,D] β-D-GlcpNAc 2.30 1TVY[A,B] α-D-Galp-(1-1)-<non_carb> 2.30 1TW1[A,B] 2.30 1TW5[A,B] β-D-GlcpNAc-(1-4)-β-D-GlcpNAc 2.30 1YRO[B,D] α-D-Galp-(1-1)-<non_carb> 1.90 2FYC[B,D] α-D-Galp-(1-1)-<non_carb> 2.00 2FYD[B,D] β-D-GalpNAc-(1-4)-β-D-Glcp 2.00 4KRV[A,B] β-D-GlcpNAc6SO3 2.40
xylosylprotein β-4-galactosyltransferase I / 7 (bGalT7/CG11780)	2.4.1.133	Drosophila melanogaster	AAF56377.1 AAM11018.1 BAC22695.1 NP_651319.2	Q8I6J0 Q8T3P3 Q9VBZ9	3LW6[A] 1.81 4LW3[A] α-D-Galp-(1-1)-<non_carb> 2.00 4LW6[A] β-D-Xylp-(1-4)-β-D-Xylp 2.40 4M4K[A] α-D-Galp-(1-1)-<non_carb> β-D-Xylp-(1-4)-β-D-Xylp 2.20
UDP-Gal: β-GlcNAc β-1,4-galactosyltransferase T1 (b4GalT1;beta4GalT-I;GalT)	2.4.1.38 2.4.1.90	Homo sapiens	CAA39073.1 AAA35935.1 AAA35936.1 AAA68218.1 AAA68219.1 AAA68220.1 AAB00776.1 AAH45773.1 AAP66230.1 ABA16640.1 ABE21039.1 ACG93380.1 BAA06188.1 BAG59480.1 BAG59940.1 BAH14665.1 CAA01685.1 CAA31611.1 CAA32247.1 CAA39074.1 CAD13306.1 CAD62044.1 CAL47686.1 CAT03462.1 CDJ98631.1 CDJ98633.1 NP_001488.2	B2R710 B4DLB8 B7ZAH9 D3DRL2 P15291 Q86XA6 W6MEN3 W6MEN4	2AE7[A,B,C] β-D-GlcpNAc-(1-2)-α-D-Manp β-D-GlcpNAc-(1-2)-α-D-Manp-(1-6)-β-D-Manp 2.00 2AEC[A,B,C] β-D-GlcpNAc-(1-2)-α-D-Manp-(1-6)-β-D-Manp 2.00 2AES[A,B,C] β-D-GlcpNAc-(1-2)-α-D-Manp-(1-3)-β-D-Manp 2.00 2AGD[A,B,C] β-D-GlcpNAc-(1-4)-α-D-Manp-(1-3)-β-D-Manp 1.90 2AH9[A,B,C] β-D-GlcpNAc-(1-4)-β-D-GlcpNAc-(1-4)-β-D-GlcpNAc 2.00 2FY7[A] 1.70 2FYA[A] 1.90 2FYB[A] 1.90 3EE5[A,B,C] β-D-GlcpNAc-(1-3)-β-D-Galp-(1-1)-<non_carb> 2.20 4EE3[A,B,C] β-D-4-deoxy-Glcp-(1-3)-β-D-GlcpNAc-(1-3)[β-D-GlcpNAc-(1-6)]-β-D-Galp-(1-4)-β-D-Glcp β-D-Galp-(1-3)-β-D-GlcpNAc-(1-3)[β-D-GlcpNAc-(1-6)]-β-D-Galp-(1-4)-β-D-Glcp 2.30 4EE4[A,B,C] β-D-GlcpNAc-(1-6)[β-D-GlcpNAc-(1-3)]-β-D-Galp-(1-4)-β-D-Glcp 1.95 4EE5[A,B,C] β-D-GlcpNAc-(1-3)-β-D-Galp-(1-4)-β-D-Glcp 2.20 4EEA[A,B,C] β-D-GlcpNAc-(1-6)-β-D-Galp-(1-4)-β-D-Glcp 2.00 4EEG[A,B,C] β-D-GlcpNAc-(1-6)-β-D-Galp 2.20 4EEM[A,B,C] β-D-GlcpNAc-(1-6)-α-D-Manp-(1-1)-methyl 2.20 4EEO[A,B,C] β-D-GlcpNAc-(1-6)-α-D-GlcpNAc-(1-1)-<non_carb> 2.30 4L41[C] 2.70 6FWT[A] 1.85 6FWU[A,B] 2.35
UDP-Gal: xylosylprotein β-1,4-galactosyltransferase-I / VII / 7 (GalT-I;B4GALT7)	2.4.1.133	Homo sapiens	AAH07317.1 AAF22225.1 AAH62983.1 AAH72403.1 AAP63346.1 AAQ88941.1 AAW16345.1 ABA31378.1 ABA36378.1 ABA37874.1 ABA37960.1 ABA68637.1 ABA69640.1 ABA70022.1 ABA70145.1 ABA82167.1 ABC03966.1 ABC16001.1 ABE23456.1 ABE26019.1 ABE26292.1 ABH64529.1 ABH64652.1 ABH64809.1 ABH66038.1 ABH70857.1 ABH70980.1 ABH72494.1 ABH75609.1 ABH99394.1 ABI02499.1 ABI07300.1 ABI10948.1 ABI12292.1 ABJ19333.1 ABJ34328.1 ABJ43360.1 ABX96323.1 ABX96633.1 ABY05097.1 ABY16036.1 ABY18833.1 ABY19001.1 ACE08824.1 ACJ96363.1 ACM85403.1 ACM95141.1 ACN00233.1 ACN08780.1 ACP73896.1 ACS06522.1 ACS08554.1 ACW23889.1 BAA83414.1 BAG51093.1 BAG51201.1 BAG53157.1 CAB56424.1 CAC24978.1 CAE90482.1 CAE91032.1 CAE93781.1 CAF14401.1 CAM55968.1 NP_009186.1	B3KMT1 B3KN39 B3KTP5 Q9UBV7 Q9UBV7	4IRP[A,B] 2.10 4IRQ[A,B,C,D] 2.30
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