Activities in Family	Glucomannan β-1,2-galactosyltransferase (EC 2.4.1.-); Glucuronoxylan α-1,2-arabinosyltransferase (EC 2.4.1.-); Glucuronoxylan β-1,2-galactosyltransferase (EC 2.4.1.-); Pectin β-1,4-glucuronyltransferase (EC 2.4.1.-); Xyloglucan β-1,2-galactosyltransferase (EC 2.4.1.-); Xyloglucan β-1,2-galacturonyltransferase (EC 2.4.1.-); UDP-GlcA: N-acetylglucosaminyl-proteoglycan β-1,4-glucuronosyltransferase (EC 2.4.1.225); UDP-Xyl: xylan β-1,4-xylosyltransferase (EC 2.4.2.-); α-1,3-L-arabinofuranosyltransferase (EC 2.4.2.-); Arabinan α-1,5-L-arabinofuranosyltransferase (EC 2.4.2.-); Xylogalacturonan β-1,3-xylosyltransferase (EC 2.4.2.41);
Mechanism	Inverting
3D Structure Status	GT-B
Note	The long animal heparan synthases are made of two domains. The N-terminal domain, which adds b-1,4-GlcA residues, belongs to family GT47 while the C-terminal domain, which adds a-1,4-GlcNAc residues, belongs to family GT64. The plant homologs, which have a single domain, display various specificities ranging from xyloglucan b-galactosyltransferase to a pectin b-glucuronyltransferase and arabinan a-L-arabinosyltransferase.
External resources	CAZypedia; Glymap;
Statistics	GenBank accession (4239); Uniprot accession (45); PDB accession (16); 3D entries (3); cryst (0)

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