Activities in Family	CMP-Neu5Ac: α-N-acetylgalactoside α-2,6-sialyltransferase (EC 2.4.3.3); CMP-Neu5Ac: β-galactoside α-2,3-sialyltransferase (EC 2.4.3.4); CMP-Neu5Ac: N-acetyllactoside α-2,3-sialyltransferase (EC 2.4.3.6); CMP-Neu5Ac : α-N-acetylneuraminate α-2,8-sialyltransferase (EC 2.4.3.8);
Mechanism	Inverting
Note	These enzymes use CMP-beta-N-acetylneuraminate as the sugar donor
External resources	CAZypedia;
Commercial Enzyme Provider(s)	CHEMILY;
Statistics	GenBank accession (528); Uniprot accession (15); PDB accession (9); 3D entries (2); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
α-2,3-sialyltransferase (Cst-I)	2.4.3.4	Campylobacter jejuni OH4384	AAF13495.1 AAS36261.1 AAT23232.1	Q9RGF1	2P2V[A] 1.85 2P56[A] 2.20
bifunctional CMP-Neu5Ac: α-2,3/-2,8-sialyltransferase (CstII;Cst-II)	2.4.3.4 2.4.3.8	Campylobacter jejuni OH4384	AAF31771.1 AAO96668.1 AAT17965.1 ABA06995.1 ABA09514.1 ABH12650.1 ABI05854.1 ACK29125.1 CAF04166.1 CAK26615.1	Q9LAK3	1RO7[A,B,C,D] 1.80 1RO8[A,B] 2.05 2DRJ[A] 2.25 2WQQ[A] 2.25 2X61[A,B] α-D-Neup5Ac-(2-3)-β-D-Galp-(1-3)-β-D-GalpNAc 1.95 2X62[A,B] 2.20 2X63[A] 2.00
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