GlycosylTransferase Family 139

Activities in FamilyGDP-Man: β-galactoside α-1,4-mannosyltransferase (EC 2.4.1.-);
Mechanism Retaining a
3D Structure StatusGT-A (AlphaFold)
NoteCreated after Kadooka et al. 2025 [PMID=40876590] who demonstrated the transferase activity of the Cryptococcus neoformans H99 protein Cgm1/Goe1, which is a β-galactoside α-(1→4)-mannosyltransferase involved in the biosynthesis of the side chain of its capsular glucuronoxylomannogalactan.
Statistics GenBank accession (233); Uniprot accession (2);
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
  β-galactoside α-1,4-mannosyltransferase (CNAG_00129;Cgm2) 2.4.1.- pubmed
Cryptococcus neoformans H99 AFR92266.1 J9VFZ3  
  β-galactoside α-1,4-mannosyltransferase (CNAG_02199;Cgm1;Goe1) 2.4.1.- pubmed
Cryptococcus neoformans H99 AFR95621.1
AFR95621.2
J9VQC4  
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