Activities in Family | UDP-GalNAc: β-1,4-N-acetylgalactosaminyltransferase (EC 2.4.1.-); |
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Mechanism | inverting (inferred) |
3D Structure Status | GT-A |
Note | Family created after Hirata et al., 2018 (PMID=29374258) who have shown that the human enzyme probably is a b-1,4-N-acetylgalactosaminyltransferase that adds GalNAc to the first mannose residue of GPI anchors; the GTs of this family are characterized by the presence of two transmembrane domains inserted in the GT-A fold; very distant relatedness to GT54 |
Statistics | GenBank accession (102); Uniprot accession (1); |
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