Glycoside Hydrolase Family 95

Mechanism	Inverting e
3D Structure Status	( α / α ) ₆ barrel
Catalytic Nucleophile/Base	Asn activated by Asp
Catalytic Proton Donor	Glu
Note	Created based on a paper by Katayama, Sakuma, Kimura, Makimura, Hiratake, Sakata, Yamanoi, Kumagai, and Yamamoto (J. Bacteriol. 2004 Aug;186(15):4885-4893)
External resources	CAZypedia;
Commercial Enzyme Provider(s)	MEGAZYME;
Statistics	GenBank accession (7699); Uniprot accession (25); PDB accession (10); 3D entries (6); cryst (0)

Summary

Download GH95 (9073) Taxonomic display Structure (6) Characterized (20) Activities in Family (3)

Bacteria
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
α-fucosidase (AmGH95A; Amuc_0186)	3.2.1.51 3.2.1.63	pubmed pubmed	Akkermansia muciniphila ATCC BAA-835	ACD04030.1 QTD80848.1	B2UM81
α-fucosidase (AmGH95B; Amuc_1120)	3.2.1.51 3.2.1.63	pubmed pubmed	Akkermansia muciniphila ATCC BAA-835	ACD04946.1 QTD79679.1	B2UR61	7ZNZ[A] 7ZO0[A]
α-L-fucosidase (BcFucA; ACS47_08840)	3.2.1.51	pubmed	Bacillus cereus MB.8-1	KXI90766.1
[xyloglucan] α-1,2-L-fucosidase (BfGH95; HMPREF9446_01800)	3.2.1.63	pubmed	Bacteroides fluxus YIT 12057	EGF57198.1	F3PST8
α-L-galactosidase (BACOVA_03438; Bovatus_03734)	3.2.1.-	pubmed	Bacteroides ovatus ATCC 8483	ALJ48339.1 EDO10805.1	A0AAN3D8J8 A7M011	4UFC[A,B]
α-L-galactosidase (cleaves L-Galp-α-1,2-D-GlcpA; BT1010)	3.2.1.-	pubmed	Bacteroides thetaiotaomicron VPI-5482	AAO76117.1 NP_809923.1	Q8A907
[xyloglucan] α-1,2-L-fucosidase (BuGH95; BACUNI_00326)	3.2.1.63	pubmed	Bacteroides uniformis ATCC 8492	EDO56039.1	A7UYF5
α-1,2-L-fucosidase (AfcA; AfuA; BbAfcA)	3.2.1.63	pubmed	Bifidobacterium bifidum JCM 1254	AAQ72464.1	Q6JV24	2EAB[A,B] 2EAC[A,B] 2EAD[A,B] 2EAE[A]
α-1,2-L-fucosidase (Blon_2335)	3.2.1.63	pubmed	Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088	ACJ53393.1	B7GNN7
α-L-fucosidase 95A (CjAfc95A;CJA_2710) (Afc95A)	3.2.1.63	pubmed	Cellvibrio japonicus Ueda107	ACE83895.1	B3PBE3
α-1,2-L-fucosidase (Afc3; CPF_2129)	3.2.1.63	pubmed	Clostridium perfringens ATCC 13124	ABG82552.1	A0A0H2YQB3 Q0TP83
[xyloglucan] α-1,2-L-fucosidase (DgGH95; HMPREF9455_00301)	3.2.1.63	pubmed	Dysgonomonas gadei ATCC BAA-286	EGJ99268.1	F5IT84
α-L-fucosidase (ATCC_00842; RUMGNA_00842; RGna_14480)	3.2.1.51 3.2.1.63	pubmed pubmed	Mediterraneibacter gnavus ATCC 29149	QHB24557.1
α-1,2-fucosidase (RiFuc95; EEG94251.1+EEG94250.1+EEG94249.1)	3.2.1.63	pubmed	Roseburia inulinivorans DSM 16841	EEG94249.1 EEG94250.1	C0FT20
α-1,2-L-fucosidase (SpGH95; SP_1654)	3.2.1.63	pubmed	Streptococcus pneumoniae TIGR4	AAK75733.1 NP_346093.1	A0A0H2UR14
α-L-fucosidase (FucWf5; AXE80_07355)	3.2.1.51	pubmed	Wenyingzhuangia fucanilytica CZ1127	ANW96103.1	A0A1B1Y5R5
α-1,2-L-fucosidase (XacAfc95; XAC1774)	3.2.1.63	doi	Xanthomonas citri pv. citri str. 306	AAM36638.1 NP_642102.1 WP_011051132.1	A0A0U5BSF5 A0A7S6Z018 A0A9X6GJM7 A0AAI7ZEX4 Q8PLM1	7KMQ[A,B]
Eukaryota
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
α-1,2-L-fucosidase (Axy8; AXY8; At4g34260) (Fuc95A)	3.2.1.63	pubmed	Arabidopsis thaliana	CAB36703.1 AAM78086.1 AAO11638.1 AEE86349.1 CAB80143.1 NP_195152.2	Q8L7W8
α-1,2-L-fucosidase (AN8149.2)	3.2.1.63	pubmed	Aspergillus nidulans FGSC A4	EAA59171.1 ABF50892.1	C8V6V7 Q5AU81
α-1,2-L-fucosidase (EBM II;LlFuc)	3.2.1.63	pubmed	Lilium longiflorum	BAF85832.1	A8J657
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