| Mechanism | Retaining e |
|---|---|
| 3D Structure Status | ( β / α ) 8 barrel |
| Catalytic Nucleophile/Base | carbonyl oxygen of C-2 acetamido group of substrate |
| Catalytic Proton Donor | Asp |
| Note | Mechanism shown in Macauley et al. (2005) JBC 280:25313-25322 |
| External resources | CAZypedia; |
| Commercial Enzyme Provider(s) | PROZOMIX; |
| Statistics | GenBank accession (4025); Uniprot accession (28); PDB accession (81); 3D entries (10); cryst (0) |
| Activity Id | EC# | Activity Name | Residue -2 | Bond -1 | Residue -1 | Reacting Bond | Residue +1 | Bond +1 | Residue +2 | Reactant |
| H25 | 3.2.1.35 | hyaluronan endo-b-1,4-N-acetylglucosaminidase | bDGlcpA | 1,3 | bDGlcpNAc | 1,4 | bDGlcpA | 1,3 | bDGlcpNAc | H2O |
| H38 | 3.2.1.52 | b-N-acetylhexosaminidase | [bDGlcpNAc/bDGalpNAc | 1,X | alcohol | H2O | ||||
| H134 | 3.2.1.169 | protein O b-N-acetylglucosaminidase | [bDGlcpNAc | 1,X | Ser/Thr | H2O | ||||
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