Mechanism	Retaining a
3D Structure Status	( α / α ) 6 barrel
Catalytic Nucleophile/Base	Asp (inferred from 3-D structure)
Catalytic Proton Donor	Asp (inferred from 3-D structure)
External resources	CAZypedia;
Statistics	GenBank accession (5694); Uniprot accession (14); PDB accession (39); 3D entries (9); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
α-1,6-mannanase (BtGH76-MD40; Btheta7330_05006)	3.2.1.101	Bacteroides thetaiotaomicron 7330	ALJ44520.1	A0A0P0FW82	6U4Z[A] 1.40
endo-α-1,6-mannanase (BT3782; BT_3782)	3.2.1.101	Bacteroides thetaiotaomicron VPI-5482	AAO78887.1 NP_812693.1	Q8A184	4MU9[A,B] 1.89
endo-α-1,6-mannanase (BT3792)	3.2.1.101	Bacteroides thetaiotaomicron VPI-5482	AAO78897.1 NP_812703.1	Q8A174	4C1S[A,B] 2.10
α-mannanase homolog (BT2949)		Bacteroides thetaiotaomicron VPI-5482	AAO78055.1 NP_811861.1		4V1R[A,B] 1.80 4V1S[A,B] 1.50
Lin0763		Listeria innocua Clip11262	CAC95995.1 NP_470105.1		3K7X[A] 1.89
endo-α-1,6-mannanase (Aman6; Enm)	3.2.1.101	Niallia circulans TN31 / TN-31 / ATCC 290101	QGY73462.1 BAA75632.1	Q9Z4P9	4BOJ[A,B,C] α-D-Manp-(1-6)-α-D-Manp 1.38 4BOK[A] 2.05 4D4A[A,B] 1.40 4D4B[A,B] α-D-Manp-(1-6)-α-D-Manp1SH6SH-(1-1)-methyl 1.30 4D4C[A,B] α-D-Manp-(1-1)-<non_carb> <carb_like_DMJ> 1.30 4D4D[A,B] α-D-Manp-(1-1)-<non_carb> <carb_like_IFM> 1.40 5AGD[A,B] α-D-Manp-(1-6)-α-D-Manp-(1-6)-α-D-Manp-(1-6)-α-D-Manp-(1-6)-α-D-Manp 1.20 5M77[A,B] α-D-Manp-(1-6)-α-D-Manp6SH-(1-1)-<non_carb> 1.46 5N0F[A,B] α-D-Manp-(1-1)-<non_carb> 1.69 6ZBM[A] 1.47 6ZBW[A,B] 1.40 6ZBX[A,B] 1.35 7NL5[A] α-D-Manp-(1-6)-α-D-Manp-(1-1)-<non_carb> 1.40
α-1,6-mannanase (ShGH76)	3.2.1.101	Salegentibacter sp. Hel_I_6	WP_037317868.1	A0A7M4DUB5 A0A7M4DUB6	6SHD[A,B,C] 2.00 6SHM[A] α-D-Manp-(1-6)-α-D-Manp-(1-6)-α-D-Manp-(1-6)-α-D-Manp 1.90 6Y8F[A] α-D-Manp-(1-6)-α-D-Manp-(1-6)-α-D-Manp 1.47
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
cell wall [GPI-anchor] α-1,6-mannotransglycosylase / α-1,6-mannanase (Dfg5; CtDfg5; CTHT_0020800)	3.2.1.101	Thermochaetoides thermophila DSM 1495	XP_006692554.1	G0S3F2	6RY0[A] 1.05 6RY1[A] α-D-Manp 1.30 6RY2[A] α-D-Manp-(1-2)-α-D-Manp 1.30 6RY5[A] α-D-Manp-(1-6)-β-D-Manp 1.30 6RY6[A] α-D-GlcpN 1.30 6RY7[A] β-D-Glcp-(1-3)-β-D-Glcp 1.30
CTHT_0025410		Thermochaetoides thermophila DSM 1495	EGS20705.1		9R4K[A] 2.02 9R4L[A] α-D-Manp 2.10 9R4M[A] α-D-Manp 1.95 9R4N[A] α-D-Manp α-D-Manp-(1-2)-α-D-Manp 2.55 9R4O[A] α-D-Manp α-D-Manp-(1-6)-α-D-Manp 2.13 9R4P[A] α-D-Manp α-D-Manp-(1-6)-α-D-Manp 2.46 9R4Q[A] α-D-Manp-(1-3)-α-D-Manp-(1-6)-α-D-Manp 2.70 9R4R[A] α-D-GlcpN 2.35 9R4S[A] β-D-Glcp β-D-Glcp-(1-3)-β-D-Glcp 2.20 9R4T[A] β-D-Glcp 2.30 9R4U[A] β-D-Glcp β-D-Glcp-(1-6)-β-D-Glcp 1.96
Top

Last update: 2025-10-28 © Copyright 1998-2025
AFMB - CNRS - Université d'Aix-Marseille