Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (35631); Uniprot accession (714); PDB accession (303); 3D entries (112); cryst (0)

Activity Id	EC#	Activity Name	Residue -2	Bond -1	Residue -1	Reacting Bond	Residue +1	Bond +1	Residue +2	Reactant
H4	3.2.1.4	cellulose endo-b-1,4-glucosidase	bDGlcp	1,4	bDGlcp	1,4	bDGlcp	1,4	bDGlcp	H2O
H5	3.2.1.6	MLG endo-b-1,3/4-glucosidase	bDGlcp	1,3/4	bDGlcp	1,3/4	bDGlcp	1,3/4	bDGlcp	H2O
H7	3.2.1.8	xylan endo-b-1,4-xylosidase	bDXylp	1,4	bDXylp	1,4	bDXylp	1,4	bDXylp	H2O
H15	3.2.1.21	b-glucosidase			[bDGlcp	1,X	alcohol			H2O
H17	3.2.1.23	b-galactosidase			[bDGalp	1,X	alcohol			H2O
H19	3.2.1.25	b-mannosidase			[bDManp	1,X	alcohol			H2O
H27	3.2.1.37	xylan exo-b-1,4-xylosidase			[bDXylp	1,4	bDXylp	1,4	bDXylp	H2O
H29	3.2.1.39	glucan endo-b-1,3-glucosidase	bDGlcp	1,3	bDGlcp	1,3	bDGlcp	1,3	bDGlcp	H2O
H32	3.2.1.45	ceramide b-glucosidase			[bDGlcp	1,X	ceramide			H2O
H33	3.2.1.46	ceramide b-galactosidase			[bDGalp	1,X	ceramide			H2O
H38	3.2.1.52	b-N-acetylhexosaminidase			[bDGlcpNAc/bDGalpNAc	1,X	alcohol			H2O
H41	3.2.1.55	a-L-arabinofuranosidase			[aLAraf	1,X	alcohol			H2O
H43	3.2.1.58	glucan exo-b-1,3-glucosidase			[bDGlcp	1,3	bDGlcp	1,3	bDGlcp	H2O
H55	3.2.1.73	MLG endo-b-1,4-glucosidase	bDGlcp	1,3/4	bDGlcp	1,4	bDGlcp	1,3/4	bDGlcp	H2O
H56	3.2.1.74	cellulose exo-b-1,4-glucosidase			[bDGlcp	1,4	bDGlcp	1,4	bDGlcp	H2O
H57	3.2.1.75	pustulan endo-b-1,6-glucosidase	bDGlcp	1,6	bDGlcp	1,6	bDGlcp	1,6	bDGlcp	H2O
H59	3.2.1.78	mannan endo-b-1,4-mannosidase	bDManp	1,4	bDManp	1,4	bDManp	1,4	bDManp	H2O
H68	3.2.1.91	cellulose exo-b-1,4-glucobiosidase	[bDGlcp	1,4	bDGlcp	1,4	bDGlcp	1,4	bDGlcp	H2O
H81	3.2.1.104	steryl b-glucosidase			[bDGlcp	1,X	sterol			H2O
H97	3.2.1.123	oligoglycan ceramide endo-b-glucosidase	bDGalp	1,4	bDGlcp	1,X	ceramide			H2O
H106	3.2.1.132	chitosan endo-b-1,4-N-glucosaminase	bDGlcpN	1,4	bDGlcpN	1,4	bDGlcpN	1,4	bDGlcpN	H2O
H114	3.2.1.146	b-galactofuranosidase			[bDGalf	1,X	alcohol			H2O
H116	3.2.1.149	primeverose b-glucosidase	[bDXylp	1,6	bDGlcp	1,X	alcohol			H2O
H117	3.2.1.150	reducing end xyloglucan exo-b-1,4-glucobiosidase	(aDXylp-1,6)bDGlcp	1,4	(aDXylp-1,6)bDGlcp	1,4	(aDXylp-1,6)bDGlcp	1,4	DGlcp]	H2O
H118	3.2.1.151	xyloglucan endo-b-1,4-glucosidase	(aDXylp-1,6)bDGlcp	1,4	bDGlcp	1,4	(aDXylp-1,6)bDGlcp	1,4	(aDXylp-1,6)bDGlcp	H2O
H129	3.2.1.164	galactan endo-b-1,6-galactosidase	bDGalp	1,6	bDGalp	1,6	bDGalp	1,6	bDGalp	H2O
H133	3.2.1.168	hesperidin 6-O-a-L-rhamnosyl-b-glucosidase	[aLRhap	1,6	bDGlcp	1,X	hesperetin			H2O
H170	3.2.1.-	glucomannan exo-b-1,3-mannosidase			[bDManp	1,3	bDManp	1,4	bDManp	H2O
H192	3.2.1.-	MLG endo-b-1,3-glucosidase	bDGlcp	1,3/4	bDGlcp	1,3	bDGlcp	1,3/4	bDGlcp	H2O
H201	3.2.1.-	arabinoxylan endo-b-1,4-xylosidase	bDXylp	1,4	(aLAraf-1,3)bDXylp	1,4	bDXylp	1,4	bDXylp	H2O
H215	3.2.1.-	rutin b-(L-rhamnosyl)-glucosidase	[aLRhap	1,6	bDGlcp	1,X	quercetin			H2O
H228	3.2.1.-	glucomannan endo-b-1,4-glucosidase	bDManp	1,4	bDGlcp	1,4	bDGlcp	1,4	bDManp	H2O
H354	3.2.1.-	mannan exo-b-1,4-mannosidase			[bDManp	1,4	bDManp	1,4	bDManp	H2O
H413	3.2.1.-	arabinoxylan endo-b-1,4-xylosidase	bDXylp	1,4	bDXylp	1,4	bDXylp	1,4	(aLAraf-1,3)bDXylp	H2O
Top