Glycoside Hydrolase Family 27

Mechanism Retaining a
ClanGH-D
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
NoteMechanistic commonality with family GH36 demonstrated by Comfort et al. (2007) Biochemistry 46:3319-3330 (PMID: 17323919).
External resourcesCAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (6345); Uniprot accession (96); PDB accession (61); 3D entries (14); cryst (0)
Activity IdEC#Activity NameResidue -2Bond -1Residue -1 Reacting BondResidue +1Bond +1Residue +2Reactant
H16 3.2.1.22 a-galactosidase [aDGalp 1,X alcohol H2O
H35 3.2.1.49 antigen a-1,3-N-acetylgalactosaminidase [aDGalpNAc 1,3 DGalp H2O
H66 3.2.1.88 b-L-arabinopyranosidase [bLArap 1,X alcohol H2O
H71 3.2.1.94 dextran exo-a-1,6-glucobiosidase [aDGlcp 1,6 aDGlcp 1,6 aDGlcp 1,6 aDGlcp H2O
H246 3.2.1.- galactomannan exo-a-1,6-galactosidase [aDGalp 1,6 bDManp 1,4 bDManp H2O
T332 2.4.1.- galactan:galactan galactosyltransferase [aDGalp 1,6 aDGalp 1,6 aDGalp a-1,6-aDGalp
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