Glycoside Hydrolase Family 190

Mechanism Inverting a
3D Structure StatusOrthogonal helix bundle + antiparallel β-sheet
NoteFamily created after the release of a 3D structure by Kim et al. [PMID=39883867] for an enzyme characterized by Gutelius et al. [PMID=24140647] a decade earlier as a peptidoglycan lytic b-1,4-muraminidase, SleC from Clostridioides difficile 630.
Statistics GenBank accession (685); Uniprot accession (1); PDB accession (1); 3D entries (1); cryst (0)
Activity IdEC#Activity NameResidue -2Bond -1Residue -1 Reacting BondResidue +1Bond +1Residue +2Reactant
L347 4.2.2.29 peptidoglycan lytic b-1,4-muraminidase bDGlcpNAc 1,4 bDMurpNAc 1,4 bDGlcpNAc 1,4 bDMurpNAc
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