Glycoside Hydrolase Family 177

Mechanism Other a,e
3D Structure StatusRossmann fold (inferred)
NoteCreated after Ishikura et al. 2003 [PMID=14614069] who demonstrated the sialidase activity of the SiaHI protein in Tannerella forsythia 92A2. All members of this family possess a N-terminal NAD+ domain.
Statistics GenBank accession (1007); Uniprot accession (2);
Activity IdEC#Activity NameResidue -2Bond -1Residue -1 Reacting BondResidue +1Bond +1Residue +2Reactant
H13 3.2.1.18 a-neuraminidase [aDNeup5NAc 2,X alcohol H2O
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