Glycoside Hydrolase Family 16 / Subf 16

Mechanism	Retaining e
Clan	GH-B
3D Structure Status	β-jelly roll
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Subfamilies established in (Viborg et al., 2019) [PMID: 31501245]
External resources	CAZypedia; PROSITE; XTH-World;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (301); Uniprot accession (40); PDB accession (10); 3D entries (7); cryst (0)

Summary

Download GH16_16 (279) Taxonomic display Structure (7) Characterized (40) Activities in Sub Family (2)

Bacteria
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D	Subf
β-agarase (AgaB34)	3.2.1.81	pubmed	Agarivorans albus YKW-34	ABW77762.1	A8W969		16
β-agarase (AgaJA3;Hz4)	3.2.1.81	doi	Agarivorans sp. JA-1 / HZ105	ADY17921.1	F1CZG0		16
β-agarase (AgaA)	3.2.1.81	pubmed	Agarivorans sp. LQ48	ACM50513.1	C9WIW7		16
endo-β-agarase (NP1_8; BuGH16B)	3.2.1.81	pubmed	Bacteroides uniformis NP1			5T9X[B,C] 5T9X[A]	16
β-agarase (YM01-3; CaCBM; CaCBM13)	3.2.1.81	pubmed	Catenovulum agarivorans YM01	AGU13985.1	T1WFD0		16
β-agarase (CaAga1; Celal_2463)	3.2.1.81	pubmed	Cellulophaga algicola DSM 14237	ADV49752.1 WP_013551224.1	E6X8Y1		16
β-agarase (Aga2)	3.2.1.81	pubmed	Cellulophaga omnivescoria	ATI14840.1	A0A291L8D8		16
β-agarase (Aga3027)	3.2.1.81	pubmed	Flammeovirga sp. OC4	AJW82061.1	A0A0D5CQX1		16
β-agarase (Aga4436)	3.2.1.81	pubmed	Flammeovirga sp. OC4	AJW82062.1	A0A0D5CRP8		16
β-agarase (AgaB)	3.2.1.81	pubmed	Flammeovirga sp. SJP92	ANN44251.1	A0A193DR42		16
β-agarase (AgaG4)	3.2.1.81	pubmed	Flammeovirga yaeyamensis MY04	ACY02061.1 ACA05043.1	B1A1A8 D0PR18		16
agarase (AgaYT)	3.2.1.81	pubmed	Flammeovirga yaeyamensis YT	AEK80424.1	G0ZDR5		16
β-agarase (AgaJ11) (acidic)	3.2.1.81	pubmed	Gayadomonas joobiniege G7	WP_040459371.1			16
β-agarase (AgaY) (extracellular)	3.2.1.81	doi	Janthinobacterium sp. SY12	ABO93616.2 ABO93616.1	A4UMV9		16
agarase (AgaA3)	3.2.1.81	doi	Microbulbifer agarilyticus JAMB-A3	BAE06228.1	Q4LFA5		16
β-agarase (AgaA7)	3.2.1.81	pubmed	Microbulbifer elongatus JAMB-A7	BAC99022.1	Q76DQ8		16
agarase (N3-1)	3.2.1.81	pubmed	Microbulbifer sp. BN3	AXY54922.1	A0A385HVW9		16
β-agarase I (AgaA; MtAgaA; MtCBM; MtCBM6)	3.2.1.81	pubmed	Microbulbifer thermotolerans JAMB-A94	BAD29947.1 BAK08910.1	Q6F4N4	3WZ1[A]	16
β-agarase (Ph1631)	3.2.1.81	pubmed	Paraglaciecola hydrolytica S66	QEP52092.1			16
neoagarabiose-producing β-agarase (PdAgaC)	3.2.1.81	pubmed	Persicobacter sp. CCB-QB2	WP_053404800.1	A0A5S8WF47	6AII[A]	16
β-agarase (BpGH16A; BACPLE_01670) (BpGH16A)	3.2.1.81	pubmed	Phocaeicola plebeius DSM 17135	EDY95404.1 WP_007560915.1	B5CY73		16
β-agarase I	3.2.1.81	pubmed	Pseudoalteromonas atlantica ATCC 19262	AAA91888.1	Q59078		16
β-agarase (AagA)	3.2.1.81	pubmed	Pseudoalteromonas gracilis B9	AAF03246.1	Q9RII9		16
β-agarase (AgaH71)	3.2.1.81	pubmed	Pseudoalteromonas hodoensis H7	AIF29515.1	A0A075IP93		16
β-agarase (AgaP)	3.2.1.81	pubmed	Pseudoalteromonas sp. AG4	ADD60418.1	D7NPL0		16
β-agarase (AgaA)	3.2.1.81	doi	Pseudoalteromonas sp. AG52	ADA72015.1	D5G3B2		16
β-agarase (AgaA) (extracellular)	3.2.1.81	pubmed	Pseudoalteromonas sp. CY24	AAN39119.2	Q8GB62		16
β-agarase (AgaA6)	3.2.1.81	doi	Pseudoalteromonas sp. JT-6	ACF40223.1	C0J1J2		16
β-porphyranase (AagA)	3.2.1.178	doi	Pseudomonas sp. ND137	BAB79291.1	Q8VUT1		16
endo-β-agarase I / B (AgaB;Sde_1175) (Aga16B)	3.2.1.81	pubmed	Saccharophagus degradans 2-40	ABD80437.1 AAT67062.1	Q21LJ2 Q6DN99		16
β-agarase I (Agy1;AgaY1)	3.2.1.81	pubmed	Saccharophagus sp. AG21	AFR90184.1	M4HPA5		16
β-agarase (DagA;SCO3471)	3.2.1.81	pubmed	Streptomyces coelicolor A3(2)	CAB61795.1 BAA84092.1 CAA29257.1 NP_627674.1	P07883 Q9S0S0		16
β-agarase (GH16B)	3.2.1.81	pubmed	unclassified Cellvibrio	WP_151030830.1			16
β-agarase I (AguB;AguD;AguK;AguH)	3.2.1.81	pubmed	uncultured bacterium	AAP49346.1 AAP49316.1 AAP70365.1 AAP70390.1	Q6XR80		16
β-agarase (AgaM1)	3.2.1.81	pubmed	uncultured bacterium	AYA70425.1	A0A385NBJ2		16
β-agarase D (AgaD)	3.2.1.81	pubmed	Vibrio sp. PO-303	BAF34350.1	Q05KJ8		16
β-agarase (AgaV)	3.2.1.81	pubmed	Vibrio sp. V134	ABL06969.1	A1E2B6		16
β-agarase D (AgaD;zobellia_4243)	3.2.1.81	pubmed	Zobellia galactanivorans DsijT	CAZ98378.1 CBM41186.1	D7GXG4	4ASM[B]	16
β-agarase B (AgaB; ZgAgaB; zobellia_3573)	3.2.1.81	pubmed	Zobellia galactanivorans DsijT	CAZ97711.1 AAF21821.1 AAO99183.1 CAC07427.1	Q9RGX8	1O4Z[A,B,C,D] 4ATF[A,B,C,D]	16
β-agarase A (AgaA; zobellia_4203)	3.2.1.81	pubmed	Zobellia galactanivorans DsijT	CAZ98338.1 AAF21820.1 AAO99182.1 AAO99184.1 CAC07425.1	G0L322 Q9RGX9	1O4Y[A] 1URX[A]	16
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