Mechanism	Retaining e
Clan	GH-B
3D Structure Status	β-jelly roll
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Many members have been assigned to subfamilies as described by Viborg et al. (2019) J Biol Chem. 2019 Sep 9 (PMID: 31501245).
External resources	CAZypedia; HOMSTRAD; PRINTS; PROSITE; XTH-World;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (24523); Uniprot accession (275); PDB accession (118); 3D entries (58); cryst (1)

Activity Id	EC#	Activity Name	Residue -2	Bond -1	Residue -1	Reacting Bond	Residue +1	Bond +1	Residue +2	Reactant
H5	3.2.1.6	MLG endo-b-1,3/4-glucosidase	bDGlcp	1,3/4	bDGlcp	1,3/4	bDGlcp	1,3/4	bDGlcp	H2O
H15	3.2.1.21	b-glucosidase			[bDGlcp	1,X	alcohol			H2O
H17	3.2.1.23	b-galactosidase			[bDGalp	1,X	alcohol			H2O
H25	3.2.1.35	hyaluronan endo-b-1,4-N-acetylglucosaminidase	bDGlcpA	1,3	bDGlcpNAc	1,4	bDGlcpA	1,3	bDGlcpNAc	H2O
H29	3.2.1.39	glucan endo-b-1,3-glucosidase	bDGlcp	1,3	bDGlcp	1,3	bDGlcp	1,3	bDGlcp	H2O
H43	3.2.1.58	glucan exo-b-1,3-glucosidase			[bDGlcp	1,3	bDGlcp	1,3	bDGlcp	H2O
H55	3.2.1.73	MLG endo-b-1,4-glucosidase	bDGlcp	1,3/4	bDGlcp	1,4	bDGlcp	1,3/4	bDGlcp	H2O
H60	3.2.1.81	agarose endo-b-1,4-galactosidase	aLGalp36An	1,3	bDGalp	1,4	aLGalp36An	1,3	bDGalp	H2O
H62	3.2.1.83	k-carrageenan endo-b-1,4-(4-sulfo)-galactosidase	aDGalp36An	1,3	bDGalp_4S	1,4	aDGalp36An	1,3	bDGalp_4S	H2O
H80	3.2.1.103	keratan sulfate endo-b-1,4-galactosidase	bDGlcpNAc	1,3	bDGalp	1,4	bDGlcpNAc	1,3	bDGalp	H2O
H118	3.2.1.151	xyloglucan endo-b-1,4-glucosidase	(aDXylp-1,6)bDGlcp	1,4	bDGlcp	1,4	(aDXylp-1,6)bDGlcp	1,4	(aDXylp-1,6)bDGlcp	H2O
H143	3.2.1.178	porphyran endo-b-1,4-galactosidase	aLGalp_6S	1,3	bDGalp	1,4	aLGalp_6S	1,3	bDGalp	H2O
H146	3.2.1.181	galactan endo-b-1,3-galactosidase	bDGalp	1,3	bDGalp	1,3	bDGalp	1,3	bDGalp	H2O
H176	3.2.1.-	galactan endo-b-1,4-galactosidase	bDGalp	1,4	bDGalp	1,4	bDGalp	1,4	bDGalp	H2O
H186	3.2.1.-	mucin endo-b-1,4-galactosidase	aDGlcpNAc	1,4	bDGalp	1,4	bDGlcpNAc	1,6	aDGalpNAc	H2O
H192	3.2.1.-	MLG endo-b-1,3-glucosidase	bDGlcp	1,3/4	bDGlcp	1,3	bDGlcp	1,3/4	bDGlcp	H2O
H224	3.2.1.-	b-carrageenase endo-b-1,4-galactosidase	aDGalp36An	1,3	bDGalp	1,4	aDGalp36An	1,3	bDGalp	H2O
T319	2.4.1.207	xyloglucan:xyloglucosyl transferase			(aDXylp-1,6)bDGlcp	1,4	DGlcp(1,6-aDXylp)			e-1,4-(aDXylp-1,6)bDGlcp
T325	2.4.1.-	b-1,3-glucanosyltransglucosidase	bDGlcp	1,3	bDGlcp	1,3	bDGlcp	1,3	bDGlcp	e-1,3-DGlcp
T326	2.4.1.-	chitin b-1,3/1,6-glucanosyltransferase	bDGlcpNAc	1,4	bDGlcpNAc	1,4	bDGlcp	1,3/6	bDGlcp	e-1,4-bDGlcpNAc
T341	2.4.1.-	b-transglycosidase	bDGlcpNAc	1,4	bDGlcpNAc	1,4	bDGlcpNAc	1,4	bDGlcpNAc	e-1,4-bDGlcpNAc
H410	3.2.1.-	MLG endo-b-1,4-glucosidase	bDGlcp	1,3	bDGlcp	1,4	bDGlcp	1,4	bDGlcp	H2O
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