Glycoside Hydrolase Family 139

Mechanism Inverting e
3D Structure Status( α / α ) 6 barrel
Catalytic Nucleophile/BaseAsn
Catalytic Proton DonorGlu
NoteCreated after Ndeh et al., Nature (2017) 544(7648):65-70 (PMID=28329766). Mechanism described by McIver et al. JBC (2025 Jun 20:110407) (PMID=40544995)
External resourcesCAZypedia;
Statistics GenBank accession (370); Uniprot accession (1); PDB accession (1); 3D entries (1); cryst (0)
Activity IdEC#Activity NameResidue -2Bond -1Residue -1 Reacting BondResidue +1Bond +1Residue +2Reactant
H211 3.2.1.- rhamnogalacturonan II exo-a-1,2-(2-Omethyl)-fucosidase [aLFucp_2OMe 1,2 bDGalp 1,2 aLAcefA H2O
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