Glycoside Hydrolase Family 123 / Subf 5

Mechanism Retaining e
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu
NoteCreated after (Sumida et al., 2011) [PMID: 21297160]. Subfamilies established according to both (Moreno Prieto et al., 2024) [PMID:38129294] and (Sumida et al., 2024) [PMID:38730244]. In the latter, group 1 is GH123_4; group 2 is GH123_5; group 3 is GH123_3; group 4 is GH123_2 and group GH123 is GH123_1.
External resourcesCAZypedia;
Statistics GenBank accession (1); Uniprot accession (0); PDB accession (2); 3D entries (1); cryst (0)
Activity IdEC#Activity NameResidue -2Bond -1Residue -1 Reacting BondResidue +1Bond +1 Residue +2Reactant
H399 3.2.1.- exo-b-1,3-N-acetylgalactosaminidase [bDGalpNAc 1,3 aDGalp 1,4 bDGalp H2O
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