Mechanism	Retaining e
Clan	GH-R
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Asp
Catalytic Proton Donor	His
Note	Created after Colin et al. (2006) Glycobiology 16, 1021-1032; structure and mechanism after Vickers et al., JBC (2018)
External resources	CAZypedia;
Statistics	GenBank accession (63); Uniprot accession (12); PDB accession (5); 3D entries (3); cryst (0)

Bacteria
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
endo-α-1,3-L-fucanase / endo-α-1,3-L-fucoidanase (Mef2)	3.2.1.211	pubmed	Flagellimonas eckloniae DOKDO 007	WP_055392200.1
endo-α-1,4-L-fucanase (Mef1; AAY42_01290)	3.2.1.212	pubmed	Flagellimonas eckloniae DOKDO 007	KQC28683.1	A0A0N8WFH1	8BPD[A]
α-1,4-endofucoidanase (Fcn1; FaFcn1; OUC-FaFcn1 )	3.2.1.212	pubmed	Flavobacterium algicola OUC	UZH25096.1
endo-α-1,4-L-fucanase (FFA2)	3.2.1.212	pubmed	Formosa algae KMM 3553	WP_057784219.1	A0A9X0YK35
endo-α-1,4-L-fucanase (FFA1)	3.2.1.212	pubmed	Formosa algae KMM 3553T	WP_057784217.1	A0A9X0YK53
endo-α-1,4-L-fucoidanase (Fhf2)	3.2.1.212	pubmed	Formosa haliotis	WP_066217784.1
endo-α-1,4-L-fucanase (Fhf1)	3.2.1.212	pubmed	Formosa haliotis	WP_066217780.1
sulfated fucan endo-α-1,4-L-fucanase (α-1,4-L-endofucoidanase; FcnA; MfFcnA)	3.2.1.212	pubmed	Mariniflexile fucanivorans	CAI47003.1	Q08I46	6DLH[A] 6DMS[A] 6DNS[A]
endo-fucoidan hydrolase (FcnA; P19DFcnA)	3.2.1.212	pubmed	Psychromonas sp. SW19D	AYF59292.1
endo-fucoidan hydrolase (FcnA; P5AFcnA)	3.2.1.212	pubmed	Psychromonas sp. SW5A	AYF59291.1	A0A452CSY7	6M8N[A]
sulfated fucan endo-α-1,4-L-fucanase (Fp277)	3.2.1.212	pubmed	uncultured bacterium	AYC81239.1	A0A386CB26
sulfated fucan endo-α-1,4-L-fucanase (Fp279)	3.2.1.212	pubmed	uncultured bacterium	AYC81240.1	A0A386CB32
sulfated fucan endo-α-1,4-L-fucanase (Fp273)	3.2.1.212	pubmed	uncultured bacterium	AYC81238.1	A0A386CB34
endo-α-1,4-L-fucanase (FWf3; AXE80_07420)	3.2.1.212	pubmed	Wenyingzhuangia fucanilytica CZ1127	ANW96115.1	A0A1B1Y5S0
endo-α-1,4-L-fucoidanase (FWf4; AXE80_07425)	3.2.1.212	pubmed	Wenyingzhuangia fucanilytica CZ1127	ANW96116.1	A0A1B1Y5R4
endo-α-1,4-L-fucoidanase (FWf2; AXE80_07310)	3.2.1.212	pubmed	Wenyingzhuangia fucanilytica CZ1127	ANW96098.1	A0A1B1Y5T6
endo-α-1,4-L-fucoidanase (FWf1; AXE80_07305)	3.2.1.212	pubmed	Wenyingzhuangia fucanilytica CZ1127	ANW96097.1	A0A1B1Y5S9
endo-α-1,3-L-fucanase	3.2.1.211	pubmed	Winogradskyella vidalii	WP_179351272.1
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