Activities in Family	Modules of approx. 150 residues found attached to various enzymes from families GH2, GH27, GH31, GH95, GH98 and GH101 . Binding to galactose and to blood group A/B-antigens demonstrated in the case of C. perfringens GH95CBM51 and GH98CBM51 respectively [Gregg KJ et al. (2008) J. Biol. Chem. 283:12604-13 PMID: 18292090].
3D Structure Status	β-sandwich
Note	Also know as NPCBM domains
Statistics	GenBank accession (3021); Uniprot accession (11); PDB accession (12); 3D entries (7); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
blood group B-specific α-galactosidase (AmGH110A; Amuc_0480 )		Akkermansia muciniphila ATCC BAA-835	ACD04318.1 QTD81127.1		8PVS[A,B]
blood group A- and B-cleaving endo-β-galactosidase (Endo-ABase;EabC)		Clostridium perfringens ATCC 10543	AAR84225.1	Q6RUF5 Q8XNK4	2VNG[A,B] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp 1.4 2VNO[A,B] α-D-Galp-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp 1.45 2VNR[A] 1.55
α-1,2-L-fucosidase (Afc3; CPF_2129)		Clostridium perfringens ATCC 13124	ABG82552.1	A0A0H2YQB3 Q0TP83	2VMG[A] β-D-Galp-(1-1)-methyl 1.90 2VMH[A] 1.50 2VMI[A] 1.70
CPF_1489		Clostridium perfringens ATCC 13124	ABG82278.1		7JRL[A] β-D-GlcpNAc 1.50 7JS4[A] 4.60
CPF_1489		Clostridium perfringens ATCC 13124	ABG82278.1		7JRL[A] β-D-GlcpNAc 1.50 7JRM[A] 2.00 7JS4[A] 4.60
endo-β-1,4-galactosidase (Sp3GH98; SpBgg98A; EABase; CGSSp3BS71_10403) (blood-group A/B-antigen-specific)		Streptococcus pneumoniae SP3-BS71	EDK74349.1	A0A0H2UKY3 A0A0H2UKY4 A5LBQ0 C1CB04	2YGL[A,B] 2.10 2YGM[A,B] α-D-Galp-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp-(1-4)-β-D-GlcpNAc 2.35
endo-β-1,4-galactosidase (Sp3GH98; SpBgg98A; EABase; CGSSp3BS71_10403) (blood-group A/B-antigen-specific)		Streptococcus pneumoniae SP3-BS71	EDK74349.1	A0A0H2UKY3 A0A0H2UKY4 A5LBQ0 C1CB04	2YGL[A,B] 2.10 2YGM[A,B] α-D-Galp-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp-(1-4)-β-D-GlcpNAc 2.35
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