Polysaccharide-Utilization Loci DataBase (PULDB)

PULDB describes Polysaccharide Utilization Loci (PULs) experimentally characterized in the literature, but also 3,956 PUL predictions in 71 Bacteroidetes species.
A PUL is a set of physically-linked genes organized around a susCD gene pair. PULs are prevalent in the Bacteroidetes phylum. They provide an evolutionary advantage to these species by orchestrating the breakdown of complex glycans thanks to the encoded CAZymes. Please note that our PUL prediction tool tends to predict more PULs with multiple tandem susCD pairs than what is seen in experimentally determined cases.

Citing PULDB

Terrapon, N., Lombard, V., Gilbert, H.J. and Henrissat, B. (2015) Automatic prediction of polysaccharide utilization loci in Bacteroidetes species from the human gut microbiota; Bioinformatics 31(5):647-55 - Link to the publication

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Enter one or multiple modules separated by + as for example GH76+GH92+GH125
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Note: [F] indicates a possibly fragmented gene (for example a missing signal peptide or an incomplete catalytic module) and [EC] denotes functional characterization of the gene in the litterature (EC number assigned by CAZy curators).