Activities in Family	Hyaluronate lyase (EC 4.2.2.1); Gellan lyase (EC 4.2.2.25); Chondroitin AC lyase (EC 4.2.2.5);
Mechanism	b-elimination
Note	This family groups together polysaccharide lyases active on hyaluronan, gellan and chondroitin sulfate (Helbert et al., PNAS (2019) [PMID=30850540])
Statistics	GenBank accession (1068); Uniprot accession (5);

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
Snas_2009		Stackebrandtia nassauensis DSM 44728	ADD41704.1			2
SBI_03639		Streptomyces bingchenggensis BCW-1	ADI06760.1			1
N0X72_02275		Streptomyces carpaticus SCPM-O-B-9993	UWM47927.1			1
J4032_11745		Streptomyces formicae 1H-GS9	UNM12122.1			2
HUT13_01775		Streptomyces harbinensis NA02264	QKV67637.1			1
SHXM_00298 (fragment)		Streptomyces hygroscopicus XM201	AQW46835.1
SIRAN7989		Streptomyces iranensis	CDR13416.1			1
HA039_06070		Streptomyces liangshanensis QMT-12	QIQ01916.1			1
DVK44_02110		Streptomyces paludis GSSD-12	AXG82304.1			1
LIV37_51375 (fragment)		Streptomyces rapamycinicus NRRL 5491	UTP36887.1			1
LIV37_51370 (fragment)		Streptomyces rapamycinicus NRRL 5491	UTP36886.1			1
P8A20_32875		Streptomyces sp. Alt3	WLQ68068.1			2
P0D76_29335		Streptomyces sp. AM 3-1-1	WEH31111.1			1
CAC01_02390		Streptomyces sp. CLI2509 CLI2905	ASY31672.1			1
Q3Y68_06720		Streptomyces sp. HUAS CX7	WKX17730.1			2
RLT59_00220		Streptomyces sp. ITFR-6	WNI27385.1			1
D1J63_06550		Streptomyces sp. KPB2	AZM74642.1			2
K4G22_12265		Streptomyces sp. MA3_2.13	UED84883.1			1
HUT15_06345		Streptomyces sp. NA03103	QKW60148.1			2
V2W30_05540 (fragment)		Streptomyces sp. Q6	WWQ62875.1
V2W30_05545 (fragment)		Streptomyces sp. Q6	WWQ62876.1
V2W30_33390		Streptomyces sp. Q6	WWQ67746.1			2
RVR_6747		Streptomyces sp. SN-593	BBA99916.1			1
SSBG_05154		Streptomyces sp. SPB074	EFG64370.1			2
KE639_06040		Streptomyces sp. V17-9	QUW94776.1			2
DMB38_25825		Streptomyces sp. WAC 06738	AZM48744.1			2
IPZ77_00805		Streptomyces sp. XC 2026	QQN76137.1			1
SSPO_019300 (fragment)		Streptomyces sporoclivatus NBRC 100767	BBJ39212.1			1
GBW32_35190		Streptomyces tsukubensis AT3	QFR98234.1			1
Strvi_3418		Streptomyces violaceusniger Tu 4113	AEM83091.1			1
SXIM_53250		Streptomyces xiamenensis 318	AKG46709.1			1
PXH66_00710		Synoicihabitans lomoniglobus LMO-M01	WED65368.1			1
PXH66_15635		Synoicihabitans lomoniglobus LMO-M01	WED63768.1			2
TF3313_2094		Tannerella forsythia 3313	BAR49558.1			1
chondroitin AC lyase (Bfo2291; BFO_2291)	4.2.2.5	Tannerella forsythia 92A2	AEW20097.1	G8UJW9		1
TFKS16_2085		Tannerella forsythia KS16	BAR52295.1			1
P0M04_29810		Telluria mixta ACM 1762	WEM95621.1			1
THTE_0808		Thermogutta terrifontis R1	ASV73410.1			2
DYE49_11065		Treponema rectale CHPA	QOS40956.1			1
ORF		uncultured bacterium	BAR73171.1			1
ORF		uncultured bacterium	BAR73170.1			1
Polysaccharide Lyase family 33		uncultured bacterium	CAI9744599.1			1
Firmicute1046_0290		uncultured Firmicutes bacterium	QGT50953.1			1
HZI73_25700		Vallitalea pronyensis FatNI3	QUI25485.1			1
HZI73_18710		Vallitalea pronyensis FatNI3	QUI24197.1			1
IMCC26134_12365		Verrucomicrobia bacterium IMCC26134	AKC84120.1			2
SAMN05444156_0428		Verrucomicrobium sp. GAS474	SDT88612.1			2
SAMN05444156_0436		Verrucomicrobium sp. GAS474	SDT88699.1			2
SAMN05444156_2445		Verrucomicrobium sp. GAS474	SDU18030.1			2
O7597_23375		Verrucosispora sp. WMMC514	WBB89902.1			1
O7601_18220		Verrucosispora sp. WMMD573	WBB52517.1			1
C5Q97_05420		Victivallales bacterium CCUG 44730	AVM44182.1			1
OLD84_16095		Virgibacillus natechei DSM 25609	UZD12412.1			2
AXE80_03240		Wenyingzhuangia fucanilytica CZ1127	ANW97412.1			2
PRU_2441		Xylanibacter ruminicola 23	ADE81006.1			1
J4031_08845		Xylanibacter ruminicola KHP1	QVJ82270.1			1
ET471_09650		Xylanimonas protaetiae FW10M-9	QAY71819.1			1
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
148027		Oidiodendron maius Zn (Oidma1)				2
2065		Pseudogymnoascus destructans 20631-21 (Pseudest1)				2
SDRG_03590		Saprolegnia diclina VS20	EQC39388.1			2
SPRG_00309		Saprolegnia parasitica CBS 223.65	KDO35462.1			2
20454		Saprolegnia parasitica CBS 223.65 (Sappar1)				2
358620		Umbelopsis sp. nov. AD052 v1.0 (Umbsp_AD052_1)				2
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