Polysaccharide Lyase Family 33

Activities in Familyhyaluronate lyase (EC 4.2.2.1); gellan lyase (EC 4.2.2.25); chondroitin sulfate lyase (EC 4.2.2.20)
Mechanism b-elimination
NoteThis family groups together polysaccharide lyases active on hyaluronan, gellan and chondroitin sulfate (Helbert et al., PNAS (2019) [PMID=30850540])
Statistics GenBank accession (696); Uniprot accession (4);
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D Subf
 endo-hyaluronan lyase (BcellWH2_04512; BACWH2_4253) 4.2.2.1 pubmed
Bacteroides cellulosilyticus WH2 ALJ61728.1 A0A0P0GKX0   1
 endo-gellan lyase (OPIT5_09595) 4.2.2.25 pubmed
Opitutaceae bacterium TAV5 AHF90411.1 W0J0V6   2
 endo-chondroitin sulfate lyase (OPIT5_11155) 4.2.2.20 pubmed
Opitutaceae bacterium TAV5 AHF90672.1 W0IWV0   2
 endo-gellan lyase (OPIT5_12920) 4.2.2.25 pubmed
Opitutaceae bacterium TAV5 AHF90976.1 W0J2L2   2
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