| Activities in Family | Hyaluronate lyase (EC 4.2.2.1); Gellan lyase (EC 4.2.2.25); Chondroitin AC lyase (EC 4.2.2.5); |
|---|---|
| Mechanism | b-elimination |
| Note | This family groups together polysaccharide lyases active on hyaluronan, gellan and chondroitin sulfate (Helbert et al., PNAS (2019) [PMID=30850540]) |
| Statistics | GenBank accession (1051); Uniprot accession (5); |
| Bacteria | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | Subf |
| endo-hyaluronan lyase (BcellWH2_04512; BACWH2_4253) | 4.2.2.1 | pubmed |
Bacteroides cellulosilyticus WH2 | ALJ61728.1 | A0A0P0GKX0 | 1 | |
| chondroitin-sulfate lyase (BT4410) | 4.2.2.5 | pubmed |
Bacteroides thetaiotaomicron VPI-5482 | AAO79515.1 | 1 | ||
| endo-gellan lyase (OPIT5_09595) | 4.2.2.25 | pubmed |
Opitutaceae bacterium TAV5 | AHF90411.1 | W0J0V6 | 2 | |
| endo-chondroitin sulfate lyase (OPIT5_11155) | 4.2.2.5 | pubmed |
Opitutaceae bacterium TAV5 | AHF90672.1 | W0IWV0 | 2 | |
| endo-gellan lyase (OPIT5_12920) | 4.2.2.25 | pubmed |
Opitutaceae bacterium TAV5 | AHF90976.1 | W0J2L2 | 2 | |
| chondroitin AC lyase (Bfo2291; BFO_2291) | 4.2.2.5 | pubmed |
Tannerella forsythia 92A2 | AEW20097.1 | G8UJW9 | 1 | |
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