Polysaccharide Lyase Family 33 / Subf 1

Activities in Sub FamilyHyaluronate lyase (EC 4.2.2.1);
Chondroitin AC lyase (EC 4.2.2.5);
Mechanism b-elimination
NoteThis family groups together polysaccharide lyases active on hyaluronan, gellan and chondroitin sulfate (Helbert et al., PNAS (2019) [PMID=30850540])
Statistics GenBank accession (721); Uniprot accession (3);
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3DSubf
 endo-hyaluronan lyase (BcellWH2_04512; BACWH2_4253) 4.2.2.1 pubmed
Bacteroides cellulosilyticus WH2 ALJ61728.1 A0A0P0GKX0   1
 chondroitin-sulfate lyase (BT_4410; BT4410) 4.2.2.5 pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO79515.1 Q89ZG7   1
 chondroitin AC lyase (Bfo2291; BFO_2291) 4.2.2.5 pubmed
Tannerella forsythia 92A2 AEW20097.1 G8UJW9   1
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