| Activities in Family | CMP-Neu5Ac:α-galactoside α-2,6-sialyltransferase (EC 2.4.99.-); CMP-Neu5Ac:α-glucoside α-2,6-sialyltransferase (EC 2.4.99.-); |
|---|---|
| Mechanism | Inverting |
| Note | Created after Romanow et al., J. Biol. Chem., 289:33945-33957 [PMID=25342753] who have shown that the C-terminal domains of bi-functional capsule polymerases from Neisseria meningitidis W and Y function as a-2,6-sialyltransferases that utilize CMP-beta-Neu5Ac as the sugar donor to build the alternating capsular polysaccharides [->6)-a-D-Gal-(1->4)-a-Neu5Ac-(2->)]n and [->6)-a-D-Glc-(1->4)-a-Neu5Ac-(2->)]n, respectively. |
| Statistics | GenBank accession (131); Uniprot accession (2); |