Activities in Family	α-1,4-glucan synthase (EC 2.4.1.-); Pullulan synthase (EC 2.4.1.-); UDP-Glc glycogen synthase / starch synthase (EC 2.4.1.11); α-1,3-glucan synthase (EC 2.4.1.183); ADP-Glc glycogen synthase / starch synthase (EC 2.4.1.21); NDP-Glc: starch glucosyltransferase (EC 2.4.1.242);
Mechanism	Retaining
3D Structure Status	GT-B
Statistics	GenBank accession (29512); Uniprot accession (196); PDB accession (20); 3D entries (8); cryst (0)

Archaea
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
UDP-Glc/ADP-Glc glycogen synthase (PAB2292)	2.4.1.11 2.4.1.21	Pyrococcus abyssi GE5	CAB49000.1 NP_125769.1	Q9V2J8	2BFW[A] 1.8 2BIS[A,B,C] D-1-deoxy-Glcp 2.8 3FRO[A,B,C] D-1-deoxy-Manp 2.50 3L01[A,B] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 2.60 5U09[A] 2.60
Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
glycogen synthase 1 (GlgA)	2.4.1.21	Agrobacterium tumefaciens A348	AAD03474.1 CAV22810.1	P0A3F3 P39670	1RZU[A,B] 2.30 1RZV[A,B] 2.30
granule bound starch synthase		Cyanobacterium sp. CLg1	AHB52786.1		6GNF[A,B,C] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp α-D-Glcp 2.20
glycogen synthase (GlgA;b3429)	2.4.1.21	Escherichia coli str. K-12 substr. MG1655	AAC76454.1 AAA23870.1 AAA58227.1 AAA98737.1 AAE32680.1 ACI76461.1 ACI76462.1 ACI76463.1 ACI76464.1 ACI76465.1 AIZ89571.1 ALI38891.1 AMC96312.1 AUG18132.1 AVI53588.1 AYG17629.1 CAP11378.1 CAV22746.1 NP_417887.1	C3SPR7 P08323 P0A6U8	2QZS[A] α-D-Glcp 2.20 2R4T[A] α-D-Glcp 2.26 2R4U[A] α-D-Glcp 2.37 3COP[A] α-D-Glcp 2.30 3CX4[A] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 2.29 3D1J[A] 3.00 3GUH[A] D-1-deoxy-Glcp 2.79
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
starch synthase IV (SsIV;At4g18240) (AtSS4)	2.4.1.21	Arabidopsis thaliana	CAA16796.1 AEE84015.1 AID66007.1 BAE98723.1 CAB78826.1 NP_193558.1	A0A068FPX2 A0A654FQP4 O49727 Q0WVX5	6GNE[A,B] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp 2.55
granule-bound starch synthase		Cyanophora paradoxa	ABW83990.1		6GNG[A,B] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 2.95
starch synthase I (SSI)	2.4.1.21	Hordeum vulgare	AAF37876.1 CAX51357.1	C3W8L3 Q9M5A3	4HLN[A] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-D-1-deoxy-Glcp 2.70
starch synthase 1 (WaxyG;Wx;Gbss1;Os06g0133000)	2.4.1.21	Oryza sativa Japonica Group	CCW36717.1 AAA33918.1 AAC61675.2 AAF72561.1 AAN77101.1 AAN77102.1 AAN77103.1 AAO33149.1 AAY22376.1 ABC17738.1 ABC17739.1 ABC17740.1 ABC17741.1 ABC17742.1 ABC17743.1 ABC17744.1 ABC17745.1 ABC17746.1 ABC17747.1 ABC17748.1 ABC17749.1 ABC17750.1 ABC17751.1 ABC17752.1 ABC17753.1 ABC17754.1 ABC17755.1 ABC17756.1 ABC17757.1 ABC17758.1 ABC17759.1 ABC17761.1 ABC17762.1 ABC17763.1 ABC17764.1 ABC17765.1 ABC17766.1 ABC17767.1 ABC17768.1 ABC17769.1 ABC17770.1 ABC17771.1 ABC17772.1 ABC17773.1 ABC17774.1 ACE88263.1 ACJ86348.1 ACJ86349.1 ACJ86350.1 ACJ86352.1 ACJ86355.1 ACJ86356.1 ACJ86360.1 ACJ86361.1 ACJ86364.1 ACJ86365.1 ACJ86366.1 ACJ86367.1 ACO48868.1 ACT52668.1 ACT52669.1 ACU82447.1 ACU82450.1 ACU82451.1 ACV52658.1 ACV52662.1 ACV52663.1 ACV52664.1 ACY26077.1 ACY41284.1 ACY56268.1 ACY56272.1 AEB52353.1 AGK90263.1 AII21926.1 AII21930.1 ALC78409.1 BAB19379.1 BAB88209.1 BAB88210.1 BAF18618.1 BAF92691.1 BAF92692.1 BAF92693.1 BAF92694.1 BAF92695.1 BAF92696.1 BAF92697.1 BAG91947.1 BAJ16183.1 BAJ16184.1 BAS95999.1 CAA37732.1 CAA41186.1 CAA44065.1 CAA46294.1 CAT81055.1 CCW36718.1 QBM91836.1 QBM91837.1	A0A076FRI5 A0A0D6DQE1 A0A0D6DQI8 A0EQG6 A0EQG8 A0EQH1 A0EQH2 A0EQH3 A0EQH5 A2Y8X2 A8QXF3 A8QXG3 A8QXG5 B3VDJ2 B7EHV0 B8XEJ0 B8XEJ1 B8XEJ2 B8XEJ4 B8XEJ7 B8XEJ8 B8XEK2 B8XEK3 B8XEK6 B8XEK7 B8XEK9 C7BA53 C7BA54 C8CBL1 C8CBL4 C8CBL5 C9DQS2 C9DQS6 C9DQS7 C9DQS8 D0TZY6 D0TZZ2 D3U2H9 F5BA67 P19395 Q0DEV5 Q8GZD6 R4JL77	3VUE[A] 2.70 3VUF[A] 3.00
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