GlycosylTransferase Family 58

Known ActivitiesDol-P-Man: dolichol pyrophosphate-mannose α-1,3-mannosyltransferase (EC 2.4.1.130); Dol-P-Man: dolichol pyrophosphate-Man5GlcNAc2 α-1,2-mannosyltransferase (EC 2.4.1.130)
Mechanism Inverting
3D Structure StatusGT-C
NoteThese enzymes use dolichol-P-mannose as the sugar donor.
External resourcesInterPro; PFAM;
Statistics GenBank accession (87); Uniprot accession (31);
Eukaryota
Protein Name EC#OrganismGenBankUniprotPDB/3D
 Dol-P-Man: α-1,3-mannosyltransferase (Alg3;At2g47760) 2.4.1.130 Arabidopsis thaliana AAC63631.1
AAL16193.1
AAP37662.1
NP_182297.1
O82244
Q944H6
 
 Dol-P-Man: dolichol pyrophosphate-Man5GlcNAc2 α-1,2-mannosyltransferase (Alg3;NOT;NOT56L) 2.4.1.130 Homo sapiens AAH02839.1
AAH04313.1
BAF82050.1
BAG60059.1
BAG61512.1
CAA70220.1
NP_005778.1
Q92685.1  
 Dol-P-Man: Man5GlcNAc2-PP-Dol α-1,3-mannosyltransferase (Alg3) 2.4.1.130 Pichia pastoris AAT72073.1 Q6DNA2  
 Dol-P-Man: Man5GlcNAc2-PP-Dol α-1,3-mannosyltransferase (Alg3;Rhk1;YBL082c;YBL0720) 2.4.1.130 Saccharomyces cerevisiae S288C AAA75352.1
CAA56024.1
CAA84904.1
NP_009471.1
P38179  
 Dol-P-Man: Man5GlcNAc2-PP-Dol α-1-3-mannosyltransferase (Alg3) 2.4.1.130 Trypanosoma brucei brucei 427 CAO98979.1 A8E112  

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.