GlycosylTransferase Family 28

Known Activities	1,2-diacylglycerol 3-β-galactosyltransferase (EC 2.4.1.46); 1,2-diacylglycerol 3-β-glucosyltransferase (EC 2.4.1.157); UDP-GlcNAc: Und-PP-MurAc-pentapeptide β-N-acetylglucosaminyltransferase (EC 2.4.1.227).
Mechanism	Inverting
3D Structure Status	GT-B
Note	Distantly related to family GT1
External resources	InterPro; PFAM;
Statistics	GenBank accession (2485); Uniprot accession (1443); PDB accession (2); 3D entries (1); cryst (0)

Summary

All (2220) Archaea (1) Bacteria (2177) Eukaryota (38) unclassified (4) Structure (1 ) Characterized (11)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
processive 1,2-diacylglycerol-3-β-glucosyltransferase (UgtP;YpfP;BSU21920)	2.4.1.157	Bacillus subtilis subsp. subtilis str. 168	AAA96624.1 AAV00989.1 CAB14110.1 NP_390075.1	P54166
UDP-Glc: 1,2-diacylglycerol / 1,2-diacyl-3-(β-glucosyl) β-glucosyltransferase (Chlo02003783;Caur_0652)	2.4.1.241	Chloroflexus aurantiacus J-10-fl	ABY33892.1	A9WFF4
UDP-GlcNAc: N-acetylmuramyl-(pentapeptide)-PP-C55 N-acetylglucosaminyltransferase (MurG;b0090)	2.4.1.227	Escherichia coli K-12 MG1655	AAC73201.1 ABA29978.1 BAA01355.1 CAA36776.1 CAA36867.1 CAA38867.1 NP_414632.1	P17443.3	1F0K[A] 1NLM[A]
diglucosyldiacylglycerol synthase (YpfP;ugt106B1)	2.4.1.-	Staphylococcus aureus COL	AAV00990.1 CAA74741.1	O86492
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
monogalactosyldiacylglycerol synthase 2 (Mgd2;Mgd;At5g20410)	2.4.1.46	Arabidopsis thaliana	AAK50066.1 AAL77739.1 ABA30500.1 ACW85889.1 AED92840.1 CAA04005.1 NP_568394.2	O82730
monogalactosyldiacylglycerol synthase 1 (Mgd1;At4g31780)	2.4.1.46	Arabidopsis thaliana	AAF65066.1 AAM12964.1 AAP68329.1 ABA30499.1 ACW85293.1 AEE85956.1 AEE85957.1 BAB12042.1 CAA19745.1 CAB79896.1 NP_194906.1	O81770
monogalactosyldiacylglycerol synthase 3 / C (Mgd3;MgdC;At2g11810)	2.4.1.46	Arabidopsis thaliana	AAD28678.2 ABH04464.1 AEC06183.1 AEC06184.1 BAB12041.1 NP_565352.1	Q9SI93
monogalactosyldiacylglycerol synthase (MGDG)	2.4.1.46	Cucumis sativus	AAC49624.1 ABA30498.1	P93115
MGDG synthase type A (GmMGD A)	2.4.1.46	Glycine max	BAB11979.1	Q9FZL4
MGDG synthase type A (NtMGD A)	2.4.1.46	Nicotiana tabacum	BAB11980.1	Q9FZL3
MGDG synthase A	2.4.1.46	Spinacia oleracea	ABA30497.1 CAB56218.1	Q9SM44

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.