GlycosylTransferase Family 12

Activities in Family[N-acetylneuraminyl]-galactosylglucosylceramide N-acetylgalactosaminyltransferase (EC 2.4.1.92).
Mechanism Inverting
3D Structure StatusGT-A
NoteDistant similarity to families GT2, GT21 and GT27
External resourcesCFG(Glycosphingolipid); Glymap;
Statistics GenBank accession (85); Uniprot accession (20);
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 HRM2_25430   Desulfobacterium autotrophicum HRM2 ACN15637.1 C0QGY8  
 Nitsa_1712   Nitratifractor salsuginis DSM 16511 ADV46958.1    
 VN12_24730   Pirellula sp. SH-Sr6A AMV35355.1    
 VN12_05845   Pirellula sp. SH-Sr6A AMV31622.1    
 VN12_24725   Pirellula sp. SH-Sr6A AMV35354.1    
 VN12_05850   Pirellula sp. SH-Sr6A AMV31623.1    
 RB11527   Rhodopirellula baltica SH 1 CAD79176.1
NP_870023.1
Q7UE72  
 RB11356   Rhodopirellula baltica SH 1 CAD79076.1
NP_869933.1
Q7UEG0  
 RB11529   Rhodopirellula baltica SH 1 CAD79177.1
NP_870024.1
Q7UE71  
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ORF   Bos taurus AAI42195.1
AAX46462.1
A5PJP7  
 β-4-N-acetylgalactosaminyltransferase (fragment)   Bos taurus ABO31119.1 A4GW66  
 ORF   Callorhinchus milii AFP01074.1    
 ORF   Callorhinchus milii AFP01609.1    
 ORF (fragment)   Callorhinchus milii AFP06454.1    
 β-1,4-N-acetyl-galactosaminyl transferase 2 (B4galnt2)   Capra hircus AKQ62925.1    
 β-1,4-N-acetyl-galactosaminyl transferase 2 (B4galnt2)   Capra hircus AKQ62924.1    
 ORF   Crotalus adamanteus AFJ49289.1    
 Unknown (protein for MGC:158609)   Danio rerio AAI29324.1 A1L229  
 Unknown (protein for IMAGE:8099879) (partial)   Danio rerio AAI34225.1
AAI53894.1
A3KP94  
 β-1,4-N-acetylgalactosaminyltransferase (B4GalnT1;GalGT;Siat2) 2.4.1.92 Homo sapiens AAA35516.1
BAD92697.1
BAG56937.1
BAG61707.1
BAX90094.1
NP_001469.1
Q00973  
 SDA β-4-N-acetylgalactosaminyltransferase (B4Galnt2;Galgt2)   Homo sapiens AAM34756.1
AAI13676.1
AAI13678.1
AAN86706.1
AAS37146.1
AAS37153.1
AAS37154.1
AAS37155.1
AAS37156.1
AAS37161.1
AAS37162.1
AAS37163.1
ABH71215.1
BAG64056.1
CAD57148.1
CAD57149.1
NP_703147.1
Q86Y40
Q8IVI2
Q8NHY0
 
 β-1,4 N-acetylgalactosaminyltransferase 1 precursor, partial (B4galnt1) (fragment)   Macaca mulatta AFE70525.1    
 β-1,4-GalNAc transferase 1 (Galgt2;Galnt4;GGM3) 2.4.1.92 Mus musculus AAA39802.1
ABV24439.1
CAM15505.1
CAM22495.1
NP_032107.1
A2A615
Q09199
 
 β-1,4-GalNAc transferase 2 (GM2/GD2 synthase;GALGT1;GALGT;GGM2 ) 2.4.1.92 Mus musculus AAA65027.1
AAA85496.1
AAH36996.1
AAH57199.1
BAE25913.1
BAX90093.1
NP_032106.1
Q09200
Q3UN35
 
 β-1,4 N-acetylgalactosaminyltransferase 2 (B4galnt2)   Mus musculus domesticus AEJ22873.1
AEJ22874.1
AEJ22876.1
   
 β-1,4 N-acetylgalactosaminyltransferase 2 (B4galnt2)   Mus musculus domesticus AEJ22872.1
AEJ22875.1
   
 β-1,4 N-acetylgalactosaminyltransferase 2 (B4galnt2)   Mus spretus AEJ22869.1    
 β-1,4 N-acetylgalactosaminyltransferase 2 (B4galnt2)   Mus spretus AEJ22870.1    
 β-1,4 N-acetylgalactosaminyltransferase 2 (B4galnt2)   Mus spretus AEJ22871.1    
 β-1,4 N-acetylgalactosaminyltransferase 2 (B4galnt2)   Mus spretus AEJ22868.1    
 β-1,4-N-acetyl-galactosaminyl transferase 1, partial (fragment)   Mustela putorius furo AER94887.1    
 β-1,4-N-acetyl-galactosaminyl transferase 1, partial (fragment)   Mustela putorius furo AER94888.1    
 β-1,4-N-acetyl-galactosaminyl transferase 2, partial (fragment)   Mustela putorius furo AER94889.1    
 β-1,4-N-acetylgalactosaminyltransferase 2 (B4galnt2)   Ovis aries AGF33390.1
AGH33861.1
   
 UDP-GalNAc: GM3 β-1,4-N-acetylgalactosaminyltransferase (GM2 synthase) (GalGT1) 2.4.1.92 Rattus norvegicus AAH81799.1
BAA04632.1
NP_074051.1
Q10468  
 ORF   Saccoglossus kowalevskii ALR88581.1    
 ORF   Saccoglossus kowalevskii ALR88591.1    
 ORF   Saccoglossus kowalevskii ALR88580.1    
 B4gn1   Salmo salar ACN10502.1 C0H8Y3  
 β-1,4-N-acetyl-galactosaminyl transferase 2   Sus scrofa ANH21179.1    
 β-1,4-N-acetylgalactosaminyltransferase   Sus scrofa domesticus AHA57453.1    
 ORF   Xenopus laevis AAH45131.1 Q7ZX76  
 Unknown (MGC:172945 IMAGE:7792876)   Xenopus tropicalis AAI59176.1 B0JZH1  
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