GlycosylTransferase Family 112

Activities in FamilyADP-glyceromannoheptose: glycoprotein O-heptosyltransferase (EC 2.4.99.-);
3D Structure StatusGT-B
NoteFamily created after Benz & Schmidt (2011) [PMID:11442838] who demonstrated the heptosyltransferase activity of the E. coli aah gene. Yao et al. [PMID:25310236] and Lu et al. [PMID:25211077] provided structural insights and highlighted the importance of the autotransporter glycosylation in several pathogenic bacteria.
Statistics GenBank accession (613); Uniprot accession (5); PDB accession (2); 3D entries (1); cryst (0)
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 ADP-D-glycero-β-D-manno-heptoside: autotransporter [glycoprotein] O-heptosyltransferase (TibC;ETEC_2140) 2.4.99.- Escherichia coli ETEC H10407 AAD46996.1
4RAP[A,B,C,D,E,F,G,H,I,J, 2.88
4RB4[A,B,C,D,E,F,G,H,I,J, 3.88

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